| Chr | chr18 |
| start | 57054558 |
| end | 57072119 |
| lncRNA name | linc-ROR |
| entrez id | 100885779 |
| hgnc id | HGNC:43773 |
| ensg id | ENSG00000258609 |
| refseq id | NR_048536 |
| methods | qPCR, Western blot, Luciferase reporter assay etc. |
| regulated | up-regulated |
| function description | Compared with immortalized MCF10A breast epithelial cells, lncRNA-ROR was highly expressed in MCF7 (nonresistant) and MDA-MB-231 (drug-resistant) cell lines. The lncRNA-ROR level was strongly elevated in the MDA-MB-231 cell line as compared to the MCF7 cell line, indicating that lncRNA-ROR can be involved in the development of breast cancer. |
| pubmed id | 28063065 |
| year | 2017 |
| title | Effects of long noncoding RNA-ROR on tamoxifen resistance of breast cancer cells by regulating microRNA-205. |
| drug | V |
| circulating | X |
| survival | X |
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