| Chr | chr18 |
| start | 57054558 |
| end | 57072119 |
| lncRNA name | linc-ROR |
| entrez id | 100885779 |
| hgnc id | HGNC:43773 |
| ensg id | ENSG00000258609 |
| refseq id | NR_048536 |
| methods | qPCR |
| regulated | up-regulated |
| function description | Among lncRNAs, large intergenic non-coding RNA regulator of reprogramming (lincRNA-ROR or linc-ROR) is a member of subvariety of lncRNAs, was first discovered in induced pluripotent stem cells (iPSCs), and plays a central role in promoting survival in iPSCs and embryonic stem cells (ESCs) through preventing the activation of cellular stress pathways.And linc-ROR also acts as a ceRNA to increase stemness gene Nanog expression by sponging miR-145 in cancer cells. |
| pubmed id | 28869448 |
| year | 2017 |
| title | Large intergenic non-coding RNA-ROR as a potential biomarker for the diagnosis and dynamic monitoring of breast cancer |
| drug | V |
| circulating | V |
| survival | V |
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