The Genomic Atlas of Breast Cancer — the non-coding theme
| Chr | NA |
| start | NA |
| end | NA |
| lncRNA name | lncRNA-CTD-2108O9.1 |
| entrez id | NA |
| hgnc id | NA |
| ensg id | NA |
| refseq id | NA |
| methods | qPCR, Western blot, in vitro knockdown etc. |
| regulated | down-regulated |
| function description | Long non-coding RNA-CTD-2108O9.1 is downregulated in BC tissues and cells and acts as a metastatic inhibitor of BC. Mechanistic investigation determined that lncRNA-CTD-2108O9.1 represses metastasis by targeting leukemia inhibitory factor receptor (LIFR), which is designated as a metastasis suppressor in BC. Our study characterizes a significant tumor suppressor active in BC metastasis repression through the known metastasis inhibitor LIFR. |
| pubmed id | 29603493 |
| year | 2017 |
| title | Long non-coding RNA-CTD-2108O9.1 represses breast cancer metastasis by influencing leukemia inhibitory factor receptor. |
| drug | V |
| circulating | X |
| survival | X |
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