Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieOvarian Cancer
CeRNA1CCAT1[LncRNA]
miRNAmiR-1290[miRNA]
CeRNA2TCF21[mRNA]
Tissue/Cell lineOvcar-8 And Skov-3,Omc685,Iose386
SpecieHomo sapiens (human)
CitationEur Rev Med Pharmacol Sci 2018 Jan 22, 322-328 doi:10.26355/eurrev_201801_14175 PMID:29424889
Reference title
LncRNA colon cancer-associated transcript 1 (CCAT1) promotes proliferation and metastasis of ovarian cancer via miR-1290.
Experimental verification
qPCR
Functional description
the expression of lncRNA CCAT1 was closely related to prognosis, tumor size, and lymph node metastasis. lncRNA CCAT1 could sponge miR-1290 in ovarian cancer. high expression of lncRNA CCAT1 could be used as an indicator of the survival time of OC patients.
Annotations
External Annotation for CCAT1 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
