LncACTdb 3.0

miRNA

CeRNA2

Sirt1[mRNA]

Tissue/Cell line

Mg63,Os-732,Hfob1.19

Specie

Homo sapiens (human)

Citation

Oncol Res 2018 Jun 11 26, 753-764 doi:10.3727/096504017x15024946480113 PMID:28810936

Reference title

LncRNA C2dat1 Promotes Cell Proliferation, Migration, and Invasion by Targeting MiR-34a-5p in Osteosarcoma Cells.

Experimental verification

Luciferase Reporter Assay,qPCR,Western blot,etc.

Functional description

C2dat1 suppression reduced cell viability,invasion and migration,while increased cell apoptosis in OS-732 cells. MiR-34a-5p was a target of C2dat1.

External Annotation for C2DAT1
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)