Detail (Experimental CeRNA)

Home Detail(Experimental CeRNA)

Basic Information

Regular Relationship :


Phenotype/DiseaseSpecie

Breast Cancer

CeRNA1

CAMTA1[LncRNA]

miRNA

miR-20b[miRNA]

CeRNA2

VEGF[mRNA]


Tissue/Cell line

Mda-Mb-231

Specie

Homo sapiens (human)

Citation

Oncol Res 2018 May 7 26, 625-635 doi:10.3727/096504017x14953948675395 PMID:28550685


Reference title
Long Noncoding RNA CAMTA1 Promotes Proliferation and Mobility of Human Breast Cancer Cell Line MDA- MB-231 Via Targeting miR-20b
Experimental verification
qPCR,Western blot,Luciferase Reporter Assays

Functional description
LncCAMTA1 might promote proliferation and mobility of human breast cancer cell via binding with miR-20b.And VEGF was directly target of miR-20b and regulated activation of MAPK/ERK and JAK/STAT3 signal pathways.

Annotations

External Annotation for CAMTA1
LncRNA-associated competing triplets and functions.
Comprehensive experimentally supported associations between lncRNA and human cancer.
Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
Information on all annotated and predicted human genes.
Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
Genome browser for vertebrate genomes.
An annotated collection of all publicly available DNA sequences.
A wiki-based platform for community curation of human long non-coding RNAs.
An integrated knowledge database dedicated to non-coding RNAs.
An integrated database of human annotated lncRNA transcripts.
Comprehensive annotations of eukaryotic long non-coding RNAs.
Comprehensive experimentally supported associations between lncRNA and human cancer.
A comprehensive, authoritative compendium of human genes and genetic phenotypes.
The catalogue of somatic mutations in cancer.

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