Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieColorectal Cancer
CeRNA1ENST00000535511[LncRNA]
miRNAmiR-133b[miRNA]
CeRNA2UBD[mRNA]
Tissue/Cell lineCRC tissues
SpecieHomo sapiens (human)
CitationOncotarget 2017 Mar 28 8, 21095-21105 doi:10.18632/oncotarget.15045 PMID:28177879
Reference title
Comprehensive analysis of differentially expressed profiles of lncRNAs and construction of miR-133b mediated ceRNA network in colorectal cancer.
Experimental verification
microarray,qPCR etc.
Functional description
qRT-PCR was performed to assess their expression levels in 14 pairs of matched colorectal tumor/non-tumor sample. This analysis revealed that miR-133b was significantly downregulated in CRC tumor samples, while UBD and lncRNA ENST00000535511 were significantly upregulated in CRC tumor samples. A significantly positive correlation between UBD and lncRNA ENST00000535511 was also observed.
Annotations
External Annotation for ENST00000535511 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
