Basic Information
Regular Relationship :
Tissue/Cell lineLn229, U251, Snb19,U87, H4,Glioma Tissues
SpecieHomo sapiens (human)
CitationOncol Res 2018 Mar 5 26, 307-313 doi:10.3727/096504017x15088061795756 PMID:29089067
Reference title
Knockdown of Long Noncoding RNA LUCAT1 Inhibits Cell Viability and Invasion by Regulating miR-375 in Glioma.
Experimental verification
qPCR,Luciferase reporter assay,in vitro knockdown etc
Functional description
LUCAT1 was substantially upregulated in glioma tissues and cells.LUCAT1 inhibition significantly suppressed the proliferation and invasion of glioma cells. The lncRNA LUCAT1 was critical for the proliferation and invasion of glioma cells by regulating miR-375.
Annotations
External Annotation for LUCAT1 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
