LncACTdb 3.0

miRNA

CeRNA2

ZEB2[mRNA]

Tissue/Cell line

Mg63 And U2-Os

Specie

Homo sapiens (human)

Citation

Oncol Res 2018 Jun 11 26, 665-673 doi:10.3727/096504017x14908298412505 PMID:28411362

Reference title

Knockdown of Long Noncoding RNA TUG1 Inhibits the Proliferation and Cellular Invasion of Osteosarcoma Cells By Sponging MiR-153

Experimental verification

qPCR,Luciferase Reporter Assays,RIP

Functional description

TUG1 was overexpressed and miR-153 was downregulated in osteosarcoma tissues and cell lines. Moreover, TUG1 was confirmed to be a miR-153 sponge.

External Annotation for TUG1
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)