Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieHepatocellular Carcinoma
CeRNA1CTBP[LncRNA]
miRNAmiR-21-5p[miRNA]
CeRNA2LAMP2[mRNA]
Tissue/Cell lineHepatocellular Carcinoma tissues
SpecieHomo sapiens (human)
CitationMol Diagn Ther 2016 Jun 20, 265-77 doi:10.1007/s40291-016-0200-9 PMID:27113935
Reference title
Evaluation of Circulatory RNA-Based Biomarker Panel in Hepatocellular Carcinoma.
Experimental verification
qPCR etc.
Functional description
We examined RNA-based biomarker panel expression level in 20 paired HCC tissues and adjacent non-tumor tissues by qRT-PCR. In tumor tissues, lncRNA-CTBP, miR-16-2, miR-21-5p expression were at a level higher than that of non-tumor tissues, with the median ratio of 421, 0.26; 12.7, 0.24; and 13.02, 0.28, respectively, compared with normal counterparts.
Annotations
External Annotation for CTBP |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
