LncACTdb 3.0

miRNA

CeRNA2

CEBPA[mRNA]

Tissue/Cell line

Primary human ADSCs

Specie

Homo sapiens (human)

Citation

Stem Cell Res 2018 Oct 32, 35-42 doi:10.1016/j.scr.2018.08.016 PMID:30172905

Reference title

LncRNA TINCR/miR-31-5p/C/EBP-Î± feedback loop modulates the adipogenic differentiation process in human adipose tissue-derived mesenchymal stem cells

Experimental verification

qPCR, Western blot, Luciferase reporter assay etc.

Functional description

Taken together, in hADSCs, lncRNA TINCR, miR-31 and C/EBP-a formed a feedback loop to modulate the adipogenic differentiation process.

External Annotation for TINCR
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)