Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieSkeletal Myogenesis
CeRNA1lnc-mg[LncRNA]
miRNAmiR-351-5p[miRNA]
CeRNA2LACTB[mRNA]
Tissue/Cell lineC57B/L6 mice
SpecieMus musculus (mouse)
CitationFaseb j 2019 Feb 33, 1911-1926 doi:10.1096/fj.201701394RRR PMID:30216112
Reference title
MicroRNA-351-5p mediates skeletal myogenesis by directly targeting lactamase-b and is regulated by lnc-mg
Experimental verification
qPCR, Luciferase reporter assay etc.
Functional description
Further analyses showed that lnc-mg acted as a molecular sponge for miR-351-5p, demonstrating its involvement in the negative regulation of LACTB by miR-351-5p during skeletal myogenesis.
Annotations
External Annotation for lnc-mg |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
