Detail (Experimental CeRNA)

Home Detail(Experimental CeRNA)

Basic Information

Regular Relationship :


Phenotype/DiseaseSpecie

Prostate Cancer

CeRNA1

FTH1 pseudogenes[Pseudogene]

miRNA

miR-638[miRNA]

CeRNA2

FTH1[mRNA]


Tissue/Cell line

DU145 and PC3

Specie

Homo sapiens (human)

Citation

Nucleic Acids Res 2018 Feb 28 46, 1998-2011 doi:10.1093/nar/gkx1248 PMID:29240947


Reference title
A FTH1 gene:pseudogene:microRNA network regulates tumorigenesis in prostate cancer
Experimental verification
qPCR, Western blot, Luciferase reporter assay etc.

Functional description
In this study, we characterize the tumor-suppressive FTH1 gene:pseudogene network. This network is targeted by miR-638 and other oncogenic miRNAs

Annotations

External Annotation for FTH1 pseudogenes
LncRNA-associated competing triplets and functions.
Comprehensive experimentally supported associations between lncRNA and human cancer.
Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
Information on all annotated and predicted human genes.
Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
Genome browser for vertebrate genomes.
An annotated collection of all publicly available DNA sequences.
A wiki-based platform for community curation of human long non-coding RNAs.
An integrated knowledge database dedicated to non-coding RNAs.
An integrated database of human annotated lncRNA transcripts.
Comprehensive annotations of eukaryotic long non-coding RNAs.
Comprehensive experimentally supported associations between lncRNA and human cancer.
A comprehensive, authoritative compendium of human genes and genetic phenotypes.
The catalogue of somatic mutations in cancer.

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