LncACTdb 3.0

miRNA

CeRNA2

DNMT1[mRNA]

Tissue/Cell line

Tissues

Specie

Homo sapiens (human)

Citation

Clin Sci (Lond) 2018 Nov 15 132, 2285-2298 doi:10.1042/cs20180403 PMID:30237316

Reference title

The downregulation of hsa_circ_0012919, sponge for miR-125a-3p, contributes to DNA methylation of CD11a and CD70 in CD4+T cells of SLE

Experimental verification

qPCR, Western blot, Luciferase reporter assay etc.

Functional description

Hsa_circ_0012919 could be regarded as a biomarker for SLE and hsa_circ_0012919 was the ceRNA for miR-125a-3p.

External Annotation for hsa_circ_0012919
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)