LncACTdb 3.0

miRNA

CeRNA2

ATG3[mRNA]

Tissue/Cell line

Bel-7402, Huh7, Hep3B, HepG2 and Chang liver

Specie

Homo sapiens (human)

Citation

Gene 2019 May 20 697, 94-102 doi:10.1016/j.gene.2019.02.036 PMID:30794914

Reference title

Long non-coding RNA PVT1 promotes autophagy as ceRNA to target ATG3 by sponging microRNA-365 in hepatocellular carcinoma

Experimental verification

qRT-PCR,Western blot,Luciferase reporter assay etc.

Functional description

In conclusion, our study demonstrated PVT1 might be a key regulator participating in autophagy in HCC cells

External Annotation for PVT1
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)