LncACTdb 3.0

miRNA

CeRNA2

ATG7[mRNA]

Tissue/Cell line

The human HCC cell lines (HCCLM3, Huh7, Hep3B, andHepG2) and a hepatocyte cell line (L02)

Specie

Homo sapiens (human)

Citation

J Cell Biochem 2019 Oct 120, 17975-17983 doi:10.1002/jcb.29064 PMID:31218739

Reference title

LncRNA CCAT1 promotes autophagy via regulating ATG7 by sponging miR-181 in hepatocellular carcinoma

Experimental verification

Western blot,RT-PCR,Luciferase reporter assay etc.

Functional description

Our findings indicate CCAT1 may play a role in regulatingautophagy by sponging miR-181a-5p in HCC.

External Annotation for CCAT1
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)