Detail (Experimental CeRNA)

Home Detail(Experimental CeRNA)

Basic Information

Regular Relationship :


Phenotype/DiseaseSpecie

Bladder Cancer

CeRNA1

CASC11[LncRNA]

miRNA

miR-150[miRNA]

CeRNA2

NA[mRNA]


Tissue/Cell line

HT-1197 and HT-1376 two urinary bladder cancer cell lines

Specie

Homo sapiens (human)

Citation

J Cell Biochem 2019 Aug 120, 13487-13493 doi:10.1002/jcb.28622 PMID:30916832


Reference title
lncRNA CASC11 promotes cancer cell proliferation in bladder cancer through miRNA-150.
Experimental verification
qRT-PCR etc.

Functional description
In conclusion, lncRNA CASC11 was upregulated, while miRNA-150 was downregulated in patients with early-stage bladder cancer. lncRNA CASC11 may promote bladder cancer cell proliferation through the inhibition of miRNA-150.

Annotations

External Annotation for CASC11
LncRNA-associated competing triplets and functions.
Comprehensive experimentally supported associations between lncRNA and human cancer.
Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
Information on all annotated and predicted human genes.
Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
Genome browser for vertebrate genomes.
An annotated collection of all publicly available DNA sequences.
A wiki-based platform for community curation of human long non-coding RNAs.
An integrated knowledge database dedicated to non-coding RNAs.
An integrated database of human annotated lncRNA transcripts.
Comprehensive annotations of eukaryotic long non-coding RNAs.
Comprehensive experimentally supported associations between lncRNA and human cancer.
A comprehensive, authoritative compendium of human genes and genetic phenotypes.
The catalogue of somatic mutations in cancer.

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