Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieHepatocellular Carcinoma
CeRNA1PAPAS[LncRNA]
miRNAmiR-188-5p[miRNA]
CeRNA2NA[mRNA]
Tissue/Cell lineTwo human HCC cell lines SNU-398 and SNU-182
SpecieHomo sapiens (human)
CitationJ Cell Biochem 2019 Aug 120, 13494-13500 doi:10.1002/jcb.28623 PMID:30920025
Reference title
LncRNA PAPAS promotes hepatocellular carcinoma by interacting with miR-188-5p.
Experimental verification
qRT-PCR etc.
Functional description
In conclusion, PAPAS is overexpressed in HCC andPAPAS may promote HCC cell proliferation by forming anegative feedback regulation circle with miR-188-5p.
Annotations
External Annotation for PAPAS |
|
|---|---|
 |
LncRNA-associated competing triplets and functions. |
 |
Comprehensive experimentally supported associations between lncRNA and human cancer. |
 |
Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
 |
Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
 |
Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
 |
Information on all annotated and predicted human genes. |
 |
Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
 |
Genome browser for vertebrate genomes. |
 |
An annotated collection of all publicly available DNA sequences. |
 |
A wiki-based platform for community curation of human long non-coding RNAs. |
 |
An integrated knowledge database dedicated to non-coding RNAs. |
 |
An integrated database of human annotated lncRNA transcripts. |
 |
Comprehensive annotations of eukaryotic long non-coding RNAs. |
 |
Comprehensive experimentally supported associations between lncRNA and human cancer. |
 |
A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
 |
The catalogue of somatic mutations in cancer. |
