Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieTemporal Lobe Epileps
CeRNA1H19[LncRNA]
miRNAlet-7b[miRNA]
CeRNA2Stat3[mRNA]
Tissue/Cell lineMale Sprague-Dawley rats (200-220 g body)
SpecieMus musculus (mouse)
CitationCell Prolif 2020 Aug 53, e12856 doi:10.1111/cpr.12856 PMID:32648622
Reference title
The lncRNA H19 binding to let-7b promotes hippocampal glial cell activation and epileptic seizures by targeting Stat3 in a rat model of temporal lobe epilepsy.
Experimental verification
etc.
Functional description
LncRNA H19 could competitively bind to let-7b to promote hippocam-pal glial cell activation and epileptic seizures by targeting Stat3 in a rat model of temporal lobe epilepsy.
Annotations
External Annotation for H19 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
