Detail (Experimental CeRNA)

Home Detail(Experimental CeRNA)

Basic Information

Regular Relationship :


Phenotype/DiseaseSpecie

Cervical Cancer

CeRNA1

CTBP1-AS2[LncRNA]

miRNA

miR-3163[miRNA]

CeRNA2

ZNF217[mRNA]


Tissue/Cell line

Human cervical cancer cell lines, including SiHa (HPV positive), HeLa (HPV positive), MS751 (HPV positive) and C33A (HPV negative) as well as the normal cervi-cal epithelial cells

Specie

Homo sapiens (human)

Citation

Cancer Cell Int 2020 20, 343 doi:10.1186/s12935-020-01430-5 PMID:32742190


Reference title
Long non-coding RNA CTBP1-AS2 enhances cervical cancer progression via up-regulation of ZNF217 through sponging miR-3163.
Experimental verification
qRT-PCR,Western blot,,Luciferase reporter assay,FISH etc.

Functional description
CTBP1-AS2 regulates CC progression via sponging miR-3163 to up-regulate ZNF217.

Annotations

External Annotation for CTBP1-AS2
LncRNA-associated competing triplets and functions.
Comprehensive experimentally supported associations between lncRNA and human cancer.
Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
Information on all annotated and predicted human genes.
Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
Genome browser for vertebrate genomes.
An annotated collection of all publicly available DNA sequences.
A wiki-based platform for community curation of human long non-coding RNAs.
An integrated knowledge database dedicated to non-coding RNAs.
An integrated database of human annotated lncRNA transcripts.
Comprehensive annotations of eukaryotic long non-coding RNAs.
Comprehensive experimentally supported associations between lncRNA and human cancer.
A comprehensive, authoritative compendium of human genes and genetic phenotypes.
The catalogue of somatic mutations in cancer.

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