Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieGastric Cancer
CeRNA1H19[LncRNA]
miRNAmiR-29a-3p[miRNA]
CeRNA2COL5A2[mRNA]
Tissue/Cell lineThe microarray datasets that compared gene expression between GC tissues and nontumorous/normal tissues were downloaded on the Gene Expression Omnibus database
SpecieHomo sapiens (human)
CitationJ Cancer 2020 11, 4933-4946 doi:10.7150/jca.45378 PMID:32742441
Reference title
The prognostic value of COL3A1/FBN1/COL5A2/SPARC-mir-29a-3p-H19 associated ceRNA network in Gastric Cancer through bioinformatic exploration.
Experimental verification
qRT-PCR etc.
Functional description
In conclusion, we have established a novel mRNA-miRNA-lncRNA ceRNA network through integrating bioinformatic analysis and experiments on clinical samples. This network is significantly associated with the prognosis of patients with GC. In addition, it may also provide some new directions for studying the molecular mechanism of GC. However, further researches are still needed to validate this network.
Annotations
External Annotation for H19 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
