LncACTdb 3.0

miRNA

CeRNA2

ZFX[mRNA]

Tissue/Cell line

The human endometrial carcinoma cell line Ishikaw

Specie

Homo sapiens (human)

Citation

Cancer Cell Int 2020 20, 359 doi:10.1186/s12935-020-01443-0 PMID:32760226

Reference title

HOXA-AS2 promotes type I endometrial carcinoma via miRNA-302c-3p-mediated regulation of ZFX.

Experimental verification

qRT-PCR,Western blot,luciferase reporter assay etc.

Functional description

Conclusions: These findings suggest that HOXA-AS2 can act as a new therapeutic target for type I endometrial cancer.

External Annotation for HOXA-AS2
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)