Basic Information
Regular Relationship :
Tissue/Cell lineThe glioma cell lines included A172, LN229, SHG44, U373-MG, U87, and U251
SpecieHomo sapiens (human)
CitationHum Cell 2020 Oct 33, 1273-1280 doi:10.1007/s13577-020-00408-9 PMID:32779154
Reference title
LncRNA NFIA-AS2 promotes glioma progression through modulating the miR-655-3p/ZFX axis.
Experimental verification
qRT-PCR,Western blot,luciferase reporter assay,RIP etc.
Functional description
In conclusion, NFIA-AS2 might be a prognostic bio-marker in glioma, and a novel network of NFIA-AS2, miR-655-3p, and ZFX in glioma was clarified in this study. NFIA-AS2 promoted glioma cell progression by spong-ing miR-655-3p to augment ZFX expression. These data would serve the purpose to explore promising therapeutic target and pave a way for better diagnosis in glioma.
Annotations
External Annotation for NFIA-AS2 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
