Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieAstrocytoma
CeRNA1SNHG17[LncRNA]
miRNAmiR-876-5p[miRNA]
CeRNA2ERLIN2[mRNA]
Tissue/Cell lineLN-215, ADF, U138 and A-382,NHA
SpecieHomo sapiens (human)
CitationBMC Cancer 2020 Sep 3 20, 839 doi:10.1186/s12885-020-07280-8 PMID:32883232
Reference title
SNHG17 drives malignant behaviors in astrocytoma by targeting miR-876-5p/ERLIN2 axis
Experimental verification
qRT-PCR,Western blot,Luciferase reporter assay
Functional description
SNHG17 could induce the progression of astrocytoma by sponging miR-876-5p to elevate the expression of ERLIN2. This study indicated that SNHG17 has a high potential to be a therapeutic target for astrocytoma.
Annotations
External Annotation for SNHG17 |
|
|---|---|
 |
LncRNA-associated competing triplets and functions. |
 |
Comprehensive experimentally supported associations between lncRNA and human cancer. |
 |
Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
 |
Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
 |
Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
 |
Information on all annotated and predicted human genes. |
 |
Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
 |
Genome browser for vertebrate genomes. |
 |
An annotated collection of all publicly available DNA sequences. |
 |
A wiki-based platform for community curation of human long non-coding RNAs. |
 |
An integrated knowledge database dedicated to non-coding RNAs. |
 |
An integrated database of human annotated lncRNA transcripts. |
 |
Comprehensive annotations of eukaryotic long non-coding RNAs. |
 |
Comprehensive experimentally supported associations between lncRNA and human cancer. |
 |
A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
 |
The catalogue of somatic mutations in cancer. |
