LncACTdb 3.0

miRNA

CeRNA2

NA[mRNA]

Tissue/Cell line

MLE-12 cells

Specie

Mus musculus (mouse)

Citation

Exp Ther Med 2021 Jul 22, 781 doi:10.3892/etm.2021.10213 PMID:34055080

Reference title

Long non-coding RNA Rian protects against experimental bronchopulmonary dysplasia by sponging miR-421

Experimental verification

RT-PCR;Dual-luciferase reporter assay;MTT assay;Western blot;

Functional description

All of these effects of Rian were markedly reversed by miR-421 mimics.

External Annotation for Rian
	LncRNA-associated competing triplets and functions.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
	Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
	Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
	Information on all annotated and predicted human genes.
	Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
	Genome browser for vertebrate genomes.
	An annotated collection of all publicly available DNA sequences.
	A wiki-based platform for community curation of human long non-coding RNAs.
	An integrated knowledge database dedicated to non-coding RNAs.
	An integrated database of human annotated lncRNA transcripts.
	Comprehensive annotations of eukaryotic long non-coding RNAs.
	Comprehensive experimentally supported associations between lncRNA and human cancer.
	A comprehensive, authoritative compendium of human genes and genetic phenotypes.
	The catalogue of somatic mutations in cancer.

Detail (Experimental CeRNA)