Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieEarly Phases Of Myogenesis
CeRNA1linc-MD1[Host gene]
miRNAmiR-133[miRNA]
CeRNA2HuR[mRNA]
Tissue/Cell lineMucle Tissues
SpecieHomo sapiens (human)
CitationMol Cell 2014 Feb 6 53, 506-14 doi:10.1016/j.molcel.2013.12.012 PMID:24440503
Reference title
A Feedforward Regulatory Loop between HuR and the Long Noncoding RNA linc-MD1 Controls Early Phases of Myogenesis
Experimental verification
Western blot;qRT-PCR;luciferase reporter assays
Functional description
We show that HuR is under the repressive control of miR-133 and that the sponging activity of linc-MD1 consolidates HuR expression in afeedforward positive loop
Annotations
External Annotation for linc-MD1 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
