Basic Information
Regular Relationship :
Phenotype/DiseaseSpecieProstate Cancer
CeRNA1hsa_circ_0036722[Circular RNA]
miRNAmiR-145-5p[miRNA]
CeRNA2SOX2[mRNA]
Tissue/Cell lineProstate Cancer
SpecieHomo sapiens (human)
CitationOncotarget 2017 Jul 11 8, 45367-45379 doi:10.18632/oncotarget.17488 PMID:28514762
Reference title
Novel circular RNA expression profiles reflect progression of patients with hypopharyngeal squamous cell carcinoma.
Experimental verification
qRT-PCR;Western blot
Functional description
Among the predicted miRNA targets of validated circRNAs, several are closely associated with cancer according to published data, and these miRNAs are considered promising candidates for future study. We further analyzed their interactions with corresponding circRNAs. The analysis included MRE sequences, miRNA seed types, AU-richness near seed sequences, and relative positions of MREs in the linearized sequences of circRNAs. A/U (marked with red bars in Table 4) near MRE facilitates accessibility, whereas G/C (marked with black bars) means low accessibility.
Annotations
External Annotation for hsa_circ_0036722 |
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LncRNA-associated competing triplets and functions. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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Infer genomic variations that disturb lncRNA-associated ceRNA regulation.. |
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Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements. |
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Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data. |
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Information on all annotated and predicted human genes. |
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Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information). |
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Genome browser for vertebrate genomes. |
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An annotated collection of all publicly available DNA sequences. |
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A wiki-based platform for community curation of human long non-coding RNAs. |
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An integrated knowledge database dedicated to non-coding RNAs. |
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An integrated database of human annotated lncRNA transcripts. |
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Comprehensive annotations of eukaryotic long non-coding RNAs. |
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Comprehensive experimentally supported associations between lncRNA and human cancer. |
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A comprehensive, authoritative compendium of human genes and genetic phenotypes. |
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The catalogue of somatic mutations in cancer. |
