Detail (Experimental CeRNA)

Home Detail(Experimental CeRNA)

Basic Information

Regular Relationship :


Phenotype/DiseaseSpecie

Diffuse Large B-Cell Lymphoma

CeRNA1

MIR155HG[LncRNA]

miRNA

miR-155[miRNA]

CeRNA2

BIC[mRNA]


Tissue/Cell line

Ramos, Jy25, Cb33, U266, Jurkat, K562, Hl60 Etc.

Specie

Homo sapiens (human)

Citation

Proc Natl Acad Sci U S A 2005 Mar 8 102, 3627-32 doi:10.1073/pnas.0500613102 PMID:15738415


Reference title
Accumulation of miR-155 and BIC RNA in human B cell lymphomas.
Experimental verification
qPCR, Northern blot etc.

Functional description
Relative to the control B cells, BIC RNA levels were elevated from 2- to 10-fold in DLBCL cells, with one sample showing an increase of >20-fold.

Annotations

External Annotation for MIR155HG
LncRNA-associated competing triplets and functions.
Comprehensive experimentally supported associations between lncRNA and human cancer.
Infer genomic variations that disturb lncRNA-associated ceRNA regulation..
Provide and annotate disease or phenotype-associated variants in human long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) or their regulatory elements.
Providing cellular-specific lncRNA-associated ceRNA networks predicted via high-throughput analysis of single-cell genomic data.
Information on all annotated and predicted human genes.
Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).
Genome browser for vertebrate genomes.
An annotated collection of all publicly available DNA sequences.
A wiki-based platform for community curation of human long non-coding RNAs.
An integrated knowledge database dedicated to non-coding RNAs.
An integrated database of human annotated lncRNA transcripts.
Comprehensive annotations of eukaryotic long non-coding RNAs.
Comprehensive experimentally supported associations between lncRNA and human cancer.
A comprehensive, authoritative compendium of human genes and genetic phenotypes.
The catalogue of somatic mutations in cancer.

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