Statistics of human chromosome localization :

Distribution information of variants (Click on the bars to browse the variants by the different chromosomes) :

Gene Species Location Variation type SNP ID Risk type Result
NCF1 Homo sapiens 7q11.23 marker D7S1870 Disease risk Negative
NCF1 Homo sapiens 7q11.23 marker D7S2518 Disease risk Negative
NCF2 Homo sapiens 1q25.3 SNP rs796860 Disease risk Negative
NCF2 Homo sapiens 1q25.3 SNP rs2296164 Disease risk Negative
NCF2 Homo sapiens 1q25.3 SNP rs3818364 Disease risk Negative
NCF2 Homo sapiens 1q25.3 SNP rs789192 Disease risk Negative
NCF2 Homo sapiens 1q25.3 SNP rs2274065 Disease risk Negative
NCF4 Homo sapiens 22q12.3 SNP rs1883112 Disease risk Negative
NCF4 Homo sapiens 22q12.3 SNP rs741999 Disease risk Negative
CYBA Homo sapiens 16q24.2 SNP rs4673 Disease risk Negative
CYBA Homo sapiens 16q24.2 SNP rs2306422 Disease risk Negative
CYBB Homo sapiens Xp21.1-p11.4 SNP rs5963310 Disease risk Negative
CYBB Homo sapiens Xp21.1-p11.4 SNP rs9330580 Disease risk Negative
GRIN1 Homo sapiens 9q34.3 clone anti-LGI1 Disease risk Negative
GRIN1 Homo sapiens 9q34.3 clone NMOSD Disease risk Negative
IL25 Homo sapiens 14q11.2 polymorphisms IL-25 exon1 Disease risk Negative
IL25 Homo sapiens 14q11.2 polymorphisms IL-25 exon2 Disease risk Negative
QKI Homo sapiens 6q26 polymorphisms V5 Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs12044852 Disease risk Negative
CD58 Homo sapiens 1p13.1 SNP rs2300747 Disease risk Negative
CD58 Homo sapiens 1p13.1 SNP rs1335532 Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP rs221775A>G Disease risk Negative
IL2 Homo sapiens 4q27 polymorphisms -475 AA Disease risk Negative
IL2 Homo sapiens 4q27 polymorphisms -475 AT Disease risk Positive
IL2 Homo sapiens 4q27 polymorphisms -475 TT Disease risk Negative
IL2 Homo sapiens 4q27 polymorphisms -475 A Disease risk Positive
IL2 Homo sapiens 4q27 polymorphisms -475 T Disease risk Negative
MBP Homo sapiens 18q23 polymorphisms locus A Disease risk Negative
MBP Homo sapiens 18q23 polymorphisms locus B Disease risk Negative
APOE Homo sapiens 19q13.32 genotype E3/E3 Disease risk Negative
APOE Homo sapiens 19q13.32 genotype E3/E4 Disease risk Negative
APOE Homo sapiens 19q13.32 genotype E3/E2 Disease risk Negative
APOE Homo sapiens 19q13.32 genotype E2/E4 Disease risk Negative
APOE Homo sapiens 19q13.32 genotype E2/E2 Disease risk Negative
IL6 Homo sapiens 7p15.3 SNP rs2069852 Disease risk Negative
BCL2 Homo sapiens 18q21.33 SNP rs2187163 Disease risk Negative
NFKB1 Homo sapiens 4q24 SNP rs7665090 Disease risk Positive
MTHFR Homo sapiens 1p36.22 genotype + + Disease risk Negative
MTHFR Homo sapiens 1p36.22 genotype + - Disease risk Negative
MTHFR Homo sapiens 1p36.22 genotype - - Disease risk Negative
MTHFR Homo sapiens 1p36.22 allel + Disease risk Negative
MTHFR Homo sapiens 1p36.22 allel - Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs4935356 Disease risk Positive
HLA-DRA Homo sapiens 6p21.32 SNP rs3135390 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs4935354 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs3177928 Disease risk Positive
HLA-DRA Homo sapiens 6p21.32 SNP rs7194 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs7195 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs1131541 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP s7196 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs7197 Disease risk Positive
HLA-DRA Homo sapiens 6p21.32 SNP rs1051336 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs111471704 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs1157343109 Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 SNP rs1041885 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs917751277 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs992067421 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs959264277 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs11597542 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs140860467 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs17149458 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722490 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs3118470 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs78556477 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs41294925 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722491 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs550805995 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722621 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP DELINSCrs146076135 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP DELINSTrs201945336 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP rs111892138 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP DELINSArs200308321 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP DELINSGAAGrs149637108 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP rs538493533 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP rs577524260 Disease risk Negative
HMGB Homo sapiens 13q12.3 SNP rs182881863 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1506 disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1507 disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1508 disease risk Positive
HLA-A Homo sapiens 6p22.1 polymorphism HLA-A11 disease risk Positive
HLA-C Homo sapiens 6p21.33 polymorphism HLA-A12 disease risk Positive
HLA-B Homo sapiens 6p21.33 polymorphism HLA-A13 disease risk Positive
ATXN2 Homo sapiens 12q24.12 polymorphism the 22 repeat length allele phenotypics risk N/A
APOE Homo sapiens 19q13.32 polymorphism e2 phenotypics risk N/A
LIF Homo sapiens 22q12.2 SNP SNP3951 disease risk Negative
LIF Homo sapiens 22q12.2 SNP SNP2680 disease risk Negative
TNFRSF1A Homo sapiens 12p13.31 polymorphism exon1 disease risk Negative
TLR7 Homo sapiens Xp22.2 polymorphism intron 6 disease risk Negative
CCL5 Homo sapiens 17q12 polymorphism RANTES-403G/A disease risk Positive
CCL5 Homo sapiens 17q12 polymorphism RANTES-28G phenotypics risk Positive
CCL5 Homo sapiens 17q12 polymorphism RANTES-28C/G disease risk Negative
TRB Homo sapiens 7q34 polymorphism TCRBV8 disease risk Negative
TRB Homo sapiens 7q34 polymorphism TCRBV11 disease risk Negative
TRB Homo sapiens 7q34 polymorphism TCRBC2 disease risk Negative
TRA Homo sapiens 14q11.2 polymorphism TCRAC1 disease risk Negative
TNF Homo sapiens 6p21.33 polymorphism TNF2 phenotypics risk Negative
PTPRC Homo sapiens 1q31.3-q32.1 polymorphism C77G disease risk Negative
PTPRC Homo sapiens 1q31.3-q32.1 polymorphism C772T disease risk Negative
HLA-C Homo sapiens 6p21.33 polymorphism 260-bp allele (allele 13) treatment risk Positive
MT-ND1 Homo sapiens N/A SNP NDUFS5 phenotypics risk Positive
MT-ND1 Homo sapiens N/A SNP NDUFS7 phenotypics risk Positive
MT-ND1 Homo sapiens N/A SNP NDUFA7 phenotypics risk Positive
TRA Homo sapiens 14q11.2 polymorphism Val disease risk Negative
TRA Homo sapiens 14q11.2 polymorphism Va6 disease risk Negative
EVI5 Homo sapiens 1p22.1 SNP rs79667032 disease risk Positive
IGSF3 Homo sapiens 1p13.1 SNP rs517857 disease risk Positive
LINC02868 Homo sapiens 1p13.1 SNP rs11583823 disease risk Positive
RUNX3 Homo sapiens 1p36.11 SNP rs335555 disease risk Positive
TRPC3 Homo sapiens 4q27 SNP rs55756717 disease risk Positive
SIM1 Homo sapiens 6q16.3 SNP rs924974 disease risk Positive
OPCML Homo sapiens 11q25 SNP rs2659624 disease risk Positive
LAIR2 Homo sapiens 19q13.42 SNP rs2161471 disease risk Positive
BIRC5 Homo sapiens 17q25.3 SNP rs9904341 phenotypics risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP HLA-DRB1*15:01(+)*04:05() disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP HLA-DRB1*15:01()*04:05(+) disease risk Positive
IFNA17 Homo sapiens 9p21.3 polymorphism N/A disease risk Negative
TRA Homo sapiens 14q11.2 polymorphism N/A disease risk Negative
TRB Homo sapiens 7q34 polymorphism N/A disease risk Negative
TRG Homo sapiens 7p14.1 polymorphism N/A disease risk Negative
TRD Homo sapiens 14q11.2 polymorphism N/A disease risk Negative
OMG Homo sapiens 17q11.2 mutation N/A disease risk Negative
EVI2A Homo sapiens 17q11.2 mutation N/A disease risk Negative
EVI2A Homo sapiens 17q11.2 mutation N/A disease risk Negative
EVI2A Homo sapiens 17q11.2 polymorphism N/A disease risk Negative
PSMB9 Homo sapiens 6p21.32 SNP N/A N/A Negative
PSMB8 Homo sapiens 6p21.32 SNP N/A N/A Negative
ABCB9 Homo sapiens 12q24.31 SNP N/A N/A Negative
TAP2 Homo sapiens 6p21.32 SNP N/A N/A Negative
TRB Homo sapiens 7q34 SNP Vβ5.2 disease risk Positive
TRB Homo sapiens 7q34 SNP Vβ6.1 disease risk Positive
TRB Homo sapiens 7q34 gene rearrangement N/A disease risk Positive
TRB Homo sapiens 7q34 Haplotype assignments N/A disease risk Positive
BTN1A1 Homo sapiens 6p22.2 alloantigens BT 101 disease risk Positive
HLA-B Homo sapiens 6p21.33 alloantigens HLA-B7 disease risk Positive
IGH Homo sapiens 14q32.33 polymorphism IghC N/A Negative
MEFV Homo sapiens 16p13.3 mutation M694V Disease risk Positive
MEFV Homo sapiens 16p13.3 mutation V726A Disease risk Negative
MEFV Homo sapiens 16p13.3 mutation E148Q Disease risk Negative
MEFV Homo sapiens 16p13.3 mutation K695R Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms HLA-A*31:01 Disease risk Positive
CD6 Homo sapiens 11q12.2 SNP rs17824933 Disease risk Positive
IRF8 Homo sapiens 16q24.1 SNP rs17445836 Disease risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149584 Disease risk Negative
TNFRSF1A Homo sapiens 12p13.31 SNP rs1860545 Disease risk Positive
TLR4 Homo sapiens 9q33.1 mutation Asp299Gly Phenotype risk Negative
TLR4 Homo sapiens 9q33.1 genotype +896 A/A Phenotype risk Negative
TLR4 Homo sapiens 9q33.1 genotype +896 A/G Phenotype risk Negative
TLR4 Homo sapiens 9q33.1 genotype +896 AG/G Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*10 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15 Phenotype risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16 Phenotype risk Negative
TRB Homo sapiens 7q34 expansion Vβ1 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ2 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ3 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ4 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ5.1 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ5.2 Disease risk Positive
TRB Homo sapiens 7q34 expansion Vβ6 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ7 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ8 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ9 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ10 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ11 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ12 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ13 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ14 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ15 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ16 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ17 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ18 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ19 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ20 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ21 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ22 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ23 Disease risk Negative
TRB Homo sapiens 7q34 expansion Vβ24 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR1 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR(2)15 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR3 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR4 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR5 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR6 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR7 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR8 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR9 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR10 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR11 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR12 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR13 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR14 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR103 Phenotype risk Negative
HLA-A Homo sapiens 6p22.1 genotype A1 Disease risk Negative
HLA-A Homo sapiens 6p22.1 genotype A2 Disease risk Negative
HLA-A Homo sapiens 6p22.1 genotype A11 Disease risk Negative
HLA-A Homo sapiens 6p22.1 genotype A24 Disease risk Negative
HLA-A Homo sapiens 6p22.1 genotype A26 Disease risk Negative
HLA-A Homo sapiens 6p22.1 genotype A39 Disease risk Negative
HLA-A Homo sapiens 6p22.1 genotype A31 Disease risk Negative
HLA-A Homo sapiens 6p22.1 genotype Aw33 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B7 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B13 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B14 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B17 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B27 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B35 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B37 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B38 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B39 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B44 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype Bw46 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype Bw48 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B51 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B52 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B54 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B55 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B56 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B59 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B60 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B61 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B62 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B67 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B70 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype B75 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype Bw4 Disease risk Negative
HLA-B Homo sapiens 6p21.33 genotype Bw6 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw1 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw3 Disease risk Positive
HLA-C Homo sapiens N/A genotype Cw9 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw10 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw4 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw5 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw6 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw7 Disease risk Negative
HLA-C Homo sapiens N/A genotype Cw11 Disease risk Negative
HLA-C Homo sapiens N/A genotype Blank (double)' Disease risk Negative
HLA-C Homo sapiens N/A genotype Blank (single) d Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR1 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR2 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 genotype DR4 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR5 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR6 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR7 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR9 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR10 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRw52 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRw53 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1502 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1601 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1602 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DQB1*0501 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DQB1*0502 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0503 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0601 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DQB1*0602 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0603 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0604 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DQB1*0301 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0302 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0303 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DQB1*0401 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0402 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*? Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0101 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0201 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0202 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0301 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0401 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0402 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0501 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0601 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0801 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*0901 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1001 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1101 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1301 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1401 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1501 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1601 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1701 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1801 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*1901 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs987107 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs987106 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs3194051 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs11567698 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs11567701 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs10461959 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs3777090 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs11567773 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs1494555 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs987107 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs987106 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs3194051 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs10058453 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs6871748 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs13169780 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs6870944 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs2303137 Disease risk Positive
VDR Homo sapiens 12q13.11 polymorphisms Taq I (rs731236) Disease risk Positive
VDR Homo sapiens 12q13.11 polymorphisms Fok I (rs2228570) Disease risk Negative
VDR Homo sapiens 12q13.11 polymorphisms Apa I(rs7975232) Disease risk Negative
SLC11A1 Homo sapiens 2q35 allele 2 Disease risk Positive
SLC11A1 Homo sapiens 2q35 allele 3 Disease risk Negative
SLC11A1 Homo sapiens 2q35 allele 5 Disease risk Negative
MBP Homo sapiens 18q23 allele 1.29 kb Disease risk Negative
MBP Homo sapiens 18q23 allele 1.27 kb Disease risk Negative
MBP Homo sapiens 18q23 allele 1.25 kb Disease risk Negative
MBP Homo sapiens 18q23 allele 1.23 kb Disease risk Negative
MBP Homo sapiens 18q23 allele 1.20kb Disease risk Negative
TNFRSF1A Homo sapiens 12p13.31 mutation R92Q Disease risk Negative
TNFRSF1A Homo sapiens 12p13.31 mutation R92Q Phenotype risk Negative
TNFRSF1A Homo sapiens 12p13.31 mutation R92Q Treatment risk Negative
AGER Homo sapiens 6p21.32 genotype 374 T/A Disease risk Positive
AGER Homo sapiens 6p21.32 homozygote AA Disease risk Positive
AGER Homo sapiens 6p21.32 genotype -479 T/C Disease risk Negative
AGER Homo sapiens 6p21.32 genotype G82S Disease risk Negative
TNFSF14 Homo sapiens 19p13.3 genotype rs1077667AA Disease risk Negative
TNFSF14 Homo sapiens 19p13.3 genotype rs1077667AG Disease risk Negative
TNFSF14 Homo sapiens 19p13.3 genotype rs1077667GG Disease risk Positive
APOE Homo sapiens 19q13.32 genotype rs405509 [ 219 G/T] Phenotype risk Negative
APOE Homo sapiens 19q13.32 genotype rs440446 [113 C/G] Phenotype risk Negative
APOE Homo sapiens 19q13.32 genotype rs440446 [113 C/C] Phenotype risk Negative
APOE Homo sapiens 19q13.32 genotype rs440446 [113 G/G] Phenotype risk Negative
APOE Homo sapiens 19q13.32 genotype rs405509 [ 219 G/G] Phenotype risk Negative
APOE Homo sapiens 19q13.32 genotype rs405509 [ 219 T/T] Phenotype risk Negative
MMP3 Homo sapiens 11q22.2 polymorphisms 5A/6A Disease risk Negative
LINE-1 Homo sapiens 1p31.3 methylation N/A Disease risk Positive
GC Homo sapiens 4q13.3 SNP rs7041 Disease risk Negative
GC Homo sapiens 4q13.3 SNP rs4588 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs118204009 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs118204011 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs118204012 Disease risk Negative
GC Homo sapiens 4q13.3 phenotype Gc1S/Gc1S Disease risk Negative
GC Homo sapiens 4q13.3 phenotype Gc1S/Gc2 Disease risk Negative
GC Homo sapiens 4q13.3 phenotype Gc1S/Gc1F Disease risk Negative
GC Homo sapiens 4q13.3 phenotype Gc1F/Gc2 Disease risk Negative
GC Homo sapiens 4q13.3 phenotype Gc2/Gc2 Disease risk Negative
GC Homo sapiens 4q13.3 phenotype Gc1F/Gc1F Disease risk Negative
BDNF Homo sapiens 11p14.1 polymorphisms 196 G/G Disease risk Negative
BDNF Homo sapiens 11p14.1 polymorphisms 196 G/A Disease risk Positive
BDNF Homo sapiens 11p14.1 polymorphisms 270 C/C Disease risk Positive
BDNF Homo sapiens 11p14.1 polymorphisms 270 C/T Disease risk Negative
SLC9A9 Homo sapiens 3q24 SNP rs2801 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs2800 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs4240552 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs6440183 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs6440184 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs10709029 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs7625330 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs9828519 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs1900647 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs1900648 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs11919382 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs1122452 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs1562495 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs6440185 Disease risk Positive
SLC9A9 Homo sapiens 3q24 SNP rs4839655 Disease risk Positive
ST8SIA1 Homo sapiens 12p12.1 SNP rs704219 Disease risk Positive
ST8SIA1 Homo sapiens 12p12.1 SNP rs2041906 Disease risk Positive
ST8SIA1 Homo sapiens 12p12.1 SNP rs1558793 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 genotype DR1 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR3 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR4 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR6 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR7.1 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR7.2/9 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR10 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR11 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR12 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DR15 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DR1 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DR3 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DR4 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DR7 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DR8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DR11 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DR13 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DR15 Disease risk Positive
HLA-B Homo sapiens 6p21.33 allele B7 Disease risk Positive
HLA-B Homo sapiens 6p21.33 allele B8 Disease risk Negative
HLA-B Homo sapiens 6p21.33 allele B12 Disease risk Negative
HLA-B Homo sapiens 6p21.33 allele B15 Disease risk Negative
HLA-B Homo sapiens 6p21.33 allele B27 Disease risk Negative
HLA-B Homo sapiens 6p21.33 allele B35 Disease risk Negative
HLA-B Homo sapiens 6p21.33 allele B40 Disease risk Negative
HLA-A Homo sapiens 6p22.1 allele A1 Disease risk Negative
HLA-A Homo sapiens 6p22.1 allele A2 Disease risk Positive
HLA-A Homo sapiens 6p22.1 allele A3 Disease risk Positive
HLA-A Homo sapiens 6p22.1 allele A9 Disease risk Negative
HLA-A Homo sapiens 6p22.1 allele A10 Disease risk Negative
HLA-A Homo sapiens 6p22.1 allele A11 Disease risk Negative
HLA-A Homo sapiens 6p22.1 allele A19 Disease risk Negative
TRB Homo sapiens 7q34 rearrangement N/A Disease risk Positive
ERVW-1 Homo sapiens 7q21.2 DNA copy number N/A Disease risk Positive
IL4 Homo sapiens 5q31.1 genotype 5V(-523) CC Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype 5V(-523) CT Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype 5V(-523) TT Disease risk Negative
IL4 Homo sapiens 5q31.1 allele 5V(-523) C Disease risk Negative
IL4 Homo sapiens 5q31.1 allele 5V(-523) T Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype E1(33) CC Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype E1(33) TT Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype E1(33) CT Disease risk Negative
IL4 Homo sapiens 5q31.1 allele E1(33) C Disease risk Negative
IL4 Homo sapiens 5q31.1 allele E1(33) T Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(709) Disease risk Positive
IL4 Homo sapiens 5q31.1 genotype I3(709) 11 Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(709) 12 Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(709) 22 Disease risk Negative
IL4 Homo sapiens 5q31.1 allele I3(709) 1 Disease risk Negative
IL4 Homo sapiens 5q31.1 allele I3(709) 2 Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(2580) CC Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(2580) CA Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(2580) AA Disease risk Negative
IL4 Homo sapiens 5q31.1 allele I3(2580) A Disease risk Negative
IL4 Homo sapiens 5q31.1 allele I3(2580) C Disease risk Negative
IL4 Homo sapiens 5q31.1 genotype 5V(-523) CC Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype 5V(-523) CT Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype 5V(-523) TT Phenotype risk Negative
IL4 Homo sapiens 5q31.1 allele 5V(-523) C Phenotype risk Positive
IL4 Homo sapiens 5q31.1 allele 5V(-523) T Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype E1(33) CC Phenotype risk Positive
IL4 Homo sapiens 5q31.1 genotype E1(33) TT Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype E1(33) CT Phenotype risk Negative
IL4 Homo sapiens 5q31.1 allele E1(33) C Phenotype risk Negative
IL4 Homo sapiens 5q31.1 allele E1(33) T Phenotype risk Positive
IL4 Homo sapiens 5q31.1 genotype E1(33) Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(709) 11 Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(709) 12 Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(709) 22 Phenotype risk Negative
IL4 Homo sapiens 5q31.1 allele I3(709) 1 Phenotype risk Negative
IL4 Homo sapiens 5q31.1 allele I3(709) 2 Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(2580) CC Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(2580) CA Phenotype risk Negative
IL4 Homo sapiens 5q31.1 genotype I3(2580) AA Phenotype risk Negative
IL4 Homo sapiens 5q31.1 allele I3(2580) A Phenotype risk Negative
IL4 Homo sapiens 5q31.1 allele I3(2580) C Phenotype risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype GCTGC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype GTCGC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype GCCCC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype ACTGC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype GCCGC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype GTTGC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype GTCGT Disease risk Negative
TGFB1 Homo sapiens 19q13.2 haplotype Rare C Disease risk Positive
TRB Homo sapiens 7q34 rearrangement N/A Disease risk Positive
NOS3 Homo sapiens 7q36.1 SNP rs2070744 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388 Disease risk Positive
MT-TT Homo sapiens N/A variation G15257A Disease risk Positive
MT-TT Homo sapiens N/A variation G15812A Disease risk Negative
GAL Homo sapiens 11q13.2 SNP rs948854 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP TaqI(rs731236) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP ApaI(rs7975232) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP FokI(rs2228570) Disease risk Positive
HLA-DRB5 Homo sapiens 6p21.32 haplotype DRB5*0101-DQA1*0102-DQB1*0602 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 haplotype DRB1*1302-DQA1*0102-DQBl*0604 Disease risk Positive
HLA-DRB5 Homo sapiens 6p21.32 polymorphisms DRB5*0101 Disease risk Negative
ID1 Homo sapiens 20q11.21 N/A N/A Disease risk Positive
IGH Homo sapiens 14q32.33 N/A IGHV1 Disease risk Positive
IGH Homo sapiens 14q32.33 N/A IGHV3 Disease risk Positive
IGKV@ Homo sapiens 2p12 N/A IGKV1 Disease risk Positive
IGKV@ Homo sapiens 2p12 N/A IGKV3 Disease risk Positive
IGKV@ Homo sapiens 2p12 N/A IGKV5 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms HLA-DRB1*15:01 Disease risk Positive
CHRNA9 Homo sapiens 4p14 SNP rs6812832 Disease risk Negative
CHRNA9 Homo sapiens 4p14 SNP rs7681304 Disease risk Negative
CHRNA9 Homo sapiens 4p14 SNP rs4861307 Disease risk Positive
CHRNA7 Homo sapiens 15q13.3 SNP rs11635209 Disease risk Positive
CHRNA7 Homo sapiens 15q13.3 SNP rs35114543 Disease risk Negative
CHRNA7 Homo sapiens 15q13.3 SNP rs2175886 Disease risk Positive
CHRNA7 Homo sapiens 15q13.3 SNP rs1604265 Disease risk Negative
CHRNA7 Homo sapiens 15q13.3 SNP rs8033518 Disease risk Positive
CHRNA7 Homo sapiens 15q13.3 SNP rs2133965 Disease risk Negative
CHRNA7 Homo sapiens 15q13.3 SNP rs6494212 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms *0101 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms *0102 Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms *0103 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms *0201 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms *0301 Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms *0401 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms *0501 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0601 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0201 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0301 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0302 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0402 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0501 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0502 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0503 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0601 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0602 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms *0603 Disease risk Negative
APOE Homo sapiens 19q13.32 genotype E o4 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs3019561 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs3019562 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs3019548 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs2905506 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs11230548 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs17824933 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs11230555 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs916811 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs11230559 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs2237997 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs11230563 Disease risk Positive
CD6 Homo sapiens 11q12.2 SNP rs2074225 Disease risk Positive
CD6 Homo sapiens 11q12.2 SNP rs12360861 Disease risk Negative
CD6 Homo sapiens 11q12.2 SNP rs650258(5) Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs7041 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs4588 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs2282679 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs4646536 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs4646537 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs703842 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs8176345 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs8176350 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2228570* (Fok1) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs7975232 (Apa1) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs1544410 (Bsm1) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs731236 (Taq1) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs11568820 (Cdx2) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs10783219 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs11168287 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs11574024 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs11574026 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs11574077 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs11574085 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs11574114 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs12581281 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs1540339 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2189480 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2107301 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2228572 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2238135 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2238136 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2239179 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2239181 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2239182 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2239185 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2239186 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2853559 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs3782905 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs3819545 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs3890734 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs4237855 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs4328262 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs4516035 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs4760648 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs4760655 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs7136534 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs739837 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs757343 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs886441 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs987849 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2283342 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2254210 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs1555439 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs1570669 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs2181874 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs2209314 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs4809960 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs6022999 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs6097797 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs6097801 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs6127119 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs912505 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs927650 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs3787555 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs2244719 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs2296241 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs2426496 Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs2585428 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs7041 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs705120 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs4588 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs2282679 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs2298850 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs1352845 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs12512631 Disease risk Negative
STAT3 Homo sapiens 17q21.2 methylation N/A Disease risk Positive
CYP24A1 Homo sapiens 20q13.2 genotype rs2248359 GG Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 genotype rs2248359 GA Disease risk Positive
CYP24A1 Homo sapiens 20q13.2 genotype rs2248359 AA Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 allel rs2248359 G Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 allel rs2248359 A Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 genotype rs703842 TT Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 genotype rs703842 TC Disease risk Positive
CYP27B1 Homo sapiens 12q14.1 genotype rs703842 CC Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 allel rs703842 T Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 allel rs703842 C Disease risk Negative
NOS1 Homo sapiens 12q24.22 allel N/A Disease risk Negative
NFKB2 Homo sapiens 10q24.32 allel N/A Disease risk Negative
FADD Homo sapiens 11q13.3 allel N/A Disease risk Negative
GZMB Homo sapiens 14q12 allel N/A Disease risk Negative
ERBB3 Homo sapiens 12q13.2 allel N/A Disease risk Negative
NGF Homo sapiens 1p13.2 allel N/A Disease risk Negative
PARP1 Homo sapiens 1q42.12 allel N/A Disease risk Negative
GNB3 Homo sapiens 12p13.31 polymorphisms C825T Disease risk Negative
CCR5 Homo sapiens 3p21.31 mutation d32 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A1 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A2 Disease risk Positive
HLA-A Homo sapiens 6p22.1 polymorphisms A3 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A9 Disease risk Positive
HLA-A Homo sapiens 6p22.1 polymorphisms A10 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A11 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms AW19 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms AW24 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A25 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A26 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A28 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A29 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms AW30 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms AW31 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms AW32 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms AW33 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B5 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B7 Disease risk Positive
HLA-B Homo sapiens 6p21.33 polymorphisms B8 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B12 Disease risk Positive
HLA-B Homo sapiens 6p21.33 polymorphisms B13 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B14 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B15 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms BW16 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B17 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B18 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms BW21 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms BW35 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B27 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms BW35 Disease risk Positive
HLA-B Homo sapiens 6p21.33 polymorphisms B37 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms BW38 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms BW39 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B40 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR1 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR2 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR3 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR4 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR5 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRW6 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR7 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A3-B7 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A1-B8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A2-B12 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms B7-B8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A3-B7 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A1-B8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A2-B12 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms B7-DR2 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms B8-DR3 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms B12-DR7 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms B35-DR 1 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A3-B7-DR2 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A1-B8-DR3 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms A2-B12-DR7 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR2-DR3 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs4894559 Disease risk Positive
TNFRSF10A Homo sapiens 8p21.3 SNP rs4872077 Disease risk Positive
TNFRSF10B Homo sapiens 8p21.3 SNP rs1001793 Disease risk Positive
TNFRSF10B Homo sapiens 8p21.3 SNP rs11779484 Disease risk Negative
TNFRSF10B Homo sapiens 8p21.3 SNP rs4460370 Disease risk Negative
TNFRSF10B Homo sapiens 8p21.3 SNP rs9314261 Disease risk Negative
TNFRSF10B Homo sapiens 8p21.3 SNP rs3924519 Disease risk Negative
IL7R Homo sapiens 5p13.2 haplotypes Hap1 Disease risk Positive
IL7R Homo sapiens 5p13.2 haplotypes Hap2 Disease risk Positive
IL7R Homo sapiens 5p13.2 haplotypes Hap3 Disease risk Negative
IL7R Homo sapiens 5p13.2 haplotypes Hap4 Disease risk Negative
LTA Homo sapiens 6p21.33 polymorphisms TNF-β NcoI Disease risk Positive
TPH2 Homo sapiens 12q21.1 SNP rs4570625– rs10506645 GC Disease risk Negative
TPH2 Homo sapiens 12q21.1 SNP rs4570625– rs10506645 TT Disease risk Positive
TPH2 Homo sapiens 12q21.1 SNP rs4570625– rs10506645 GT Disease risk Negative
TPH2 Homo sapiens 12q21.1 SNP rs4570625– rs10506645 TC Disease risk Positive
MTNR1B Homo sapiens 11q14.3 SNP rs10830963– rs4753426 CT Disease risk Negative
MTNR1B Homo sapiens 11q14.3 SNP rs10830963– rs4753426 GC Disease risk Positive
MTNR1B Homo sapiens 11q14.3 SNP rs10830963– rs4753426 CC Disease risk Negative
MTNR1B Homo sapiens 11q14.3 SNP rs10830963– rs4753426 GT Disease risk Positive
RPS6KB1 Homo sapiens 17q23.1 SNP rs180515 Disease risk Positive
RPS6KB1 Homo sapiens 17q23.1 SNP rs180515 AA Disease risk Positive
RPS6KB1 Homo sapiens 17q23.1 SNP rs180515 AG Disease risk Negative
RPS6KB1 Homo sapiens 17q23.1 SNP rs180515 GG Disease risk Positive
CD86 Homo sapiens 3q13.33 SNP rs9282641 Disease risk Positive
CD86 Homo sapiens 3q13.33 SNP rs9282641 GG Disease risk Positive
CD86 Homo sapiens 3q13.33 SNP rs9282641 AG Disease risk Positive
CD86 Homo sapiens 3q13.33 SNP rs9282641 AA Disease risk Negative
HERV-K18 Homo sapiens 1q23.3 polymorphisms SU Disease risk Negative
Galc Homo sapiens 12 E; 12 49.83 cM mutation GALC +/- Disease risk Positive
NAT1 Homo sapiens 8p22 SNP rs7388368 Disease risk Positive
NAT1 Homo sapiens 8p22 SNP rs4921877 Disease risk Negative
NAT1 Homo sapiens 8p22 SNP rs6586711 Disease risk Negative
IFNG Homo sapiens 12q15 marker D12S1676 Disease risk Negative
IFNG Homo sapiens 12q15 marker D12S375 Disease risk Positive
IFNG Homo sapiens 12q15 marker D12S1680 Disease risk Negative
IFNG Homo sapiens 12q15 marker D12S1052 Disease risk Negative
TGFB1 Homo sapiens 19q13.2 genotype +869 TT Disease risk Negative
TGFB1 Homo sapiens 19q13.2 genotype +869 TC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 genotype +869 CC Disease risk Positive
TGFB1 Homo sapiens 19q13.2 allel +869 C Disease risk Positive
TGFB1 Homo sapiens 19q13.2 allel +869 T Disease risk Negative
TGFB1 Homo sapiens 19q13.2 genotype +915 GG Disease risk Negative
TGFB1 Homo sapiens 19q13.2 genotype +915 GC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 genotype +915 CC Disease risk Negative
TGFB1 Homo sapiens 19q13.2 allel +915 G Disease risk Negative
TGFB1 Homo sapiens 19q13.2 allel +915 C Disease risk Negative
FOXP3 Homo sapiens Xp11.23 genotype rs3761548 CC Disease risk Negative
FOXP3 Homo sapiens Xp11.23 genotype rs3761548 CA Disease risk Negative
FOXP3 Homo sapiens Xp11.23 genotype rs3761548 AA Disease risk Positive
FOXP3 Homo sapiens Xp11.23 allel rs3761548 C Disease risk Negative
FOXP3 Homo sapiens Xp11.23 allel rs3761548 A Disease risk Positive
FOXP3 Homo sapiens Xp11.23 genotype rs3761548 CC Disease risk Positive
FOXP3 Homo sapiens Xp11.23 genotype rs3761548 CA Disease risk Positive
FOXP3 Homo sapiens Xp11.23 genotype rs3761548 AA Disease risk Positive
FOXP3 Homo sapiens Xp11.23 allel rs3761548 C Disease risk Positive
FOXP3 Homo sapiens Xp11.23 allel rs3761548 A Disease risk Positive
FOXP3 Homo sapiens Xp11.23 allel rs3761548 C Disease risk Negative
FOXP3 Homo sapiens Xp11.23 allel rs3761548 A Disease risk Negative
CD45 Homo sapiens 1q31.3-q32.1 mutation C77G Disease risk Positive
CTSS Homo sapiens 1q21.3 SNP rs2275235a Phenotype risk Positive
CTSS Homo sapiens 1q21.3 SNP rs1415148a Phenotype risk Positive
TRB Homo sapiens 7q34 SNP rs71878b Phenotype risk Positive
MBP Homo sapiens 18q23 SNP rs470929a Phenotype risk Positive
CD86 Homo sapiens 3q13.33 SNP rs2001791a Phenotype risk Positive
CD86 Homo sapiens 3q13.33 SNP 1129055a Phenotype risk Positive
IL1R1 Homo sapiens 2q11.2-q12.1 SNP rs956730a Phenotype risk Positive
FAS Homo sapiens 10q23.31 SNP rs982764a Phenotype risk Positive
TRB Homo sapiens 7q34 SNP rs71878c Phenotype risk Positive
IL12RB2 Homo sapiens 1p31.3 SNP rs946685c Phenotype risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR1 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR2 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR3 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR4 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR5 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw6 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR7 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw9 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw10 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw1 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR1 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR2 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR3 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR4 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR5 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw6 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR7 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw8 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw9 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw10 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRw1 Phenotype risk Negative
IL1RN Homo sapiens 2q14.1 polymorphisms VNTR Disease risk Negative
IL1B Homo sapiens 2q14.1 polymorphisms -511 Disease risk Negative
IL1B Homo sapiens 2q14.1 polymorphisms +3,953 Disease risk Negative
IL1RN Homo sapiens 2q14.1 polymorphisms VNTR Phenotype risk Negative
IL1B Homo sapiens 2q14.1 polymorphisms -511 Phenotype risk Negative
IL1B Homo sapiens 2q14.1 polymorphisms +3,953 Phenotype risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms HLA-DRB115 Phenotype risk Positive
HLA-A Homo sapiens 6p22.1 polymorphisms A2 Phenotype risk Positive
HLA-B Homo sapiens 6p21.33 polymorphisms B7 Phenotype risk Positive
ITGA4 Homo sapiens 2q31.3 polymorphism A3061G Phenotypic risk Negative
ITGA4 Homo sapiens 2q31.3 polymorphism A-269C Phenotypic risk Negative
MX1 Homo sapiens 21q22.3 SNP rs2071430 Treatment risk Negative
MX1 Homo sapiens 21q22.3 SNP rs17000900 Treatment risk Negative
IL4 Homo sapiens 5q31.1 SNP rs2243250 Disease risk Positive
ANKRD55 Homo sapiens 5q11.2 SNP rs6859219 Disease risk Positive
DHCR7 Homo sapiens 11q13.4 SNP rs12785878 Disease risk Negative
AFF3 Homo sapiens 2q11.2 SNP rs11676922 Disease risk Negative
CCR6 Homo sapiens 6q27 SNP rs6859219 Disease risk Negative
CYP2R1 Homo sapiens 11p15.2 SNP rs10741657 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs706778 Disease risk Negative
IL10 Homo sapiens 1q32.1 SNP rs3024505 Disease risk Negative
PRDM1 Homo sapiens 6q21 SNP rs548234 Disease risk Negative
PRDM1 Homo sapiens 6q21 SNP rs7746082 Disease risk Negative
PXK Homo sapiens 3p14.3 SNP rs13315591 Disease risk Negative
SERPINE1 Homo sapiens 7q22.1 polymorphism 5G5G Disease risk Positive
SERPINE1 Homo sapiens 7q22.1 polymorphism 4G4G Disease risk Positive
CBLB Homo sapiens 3q13.11 SNP rs9657904 Disease risk Positive
PRL Homo sapiens 6p22.3 polymorphism G-1149T Disease risk Negative
PRL Homo sapiens 6p22.3 polymorphism IVS3-C214T Disease risk Negative
PRL Homo sapiens 6p22.3 polymorphism IVS3-G1220A Disease risk Negative
PRL Homo sapiens 6p22.3 polymorphism IVS4-G2243A Disease risk Negative
PRL Homo sapiens 6p22.3 polymorphism G671A Disease risk Negative
PRLR Homo sapiens 5p13.2 polymorphism C-524G Disease risk Negative
PRLR Homo sapiens 5p13.2 polymorphism T-435C Disease risk Negative
PRLR Homo sapiens 5p13.2 polymorphism IVS9-G1158A Disease risk Negative
PRLR Homo sapiens 5p13.2 polymorphism IVS10-A1870T Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 polymorphism HLA-DR15 Phenotypic risk Positive
HLA-DRA Homo sapiens 6p21.32 polymorphism HLA-DR16 Phenotypic risk Negative
IGHG1 Homo sapiens 14q32.33 polymorphism IgG CG1 Disease risk Negative
IGHG1 Homo sapiens 14q32.33 polymorphism IgG CG2 Disease risk Negative
IGHG1 Homo sapiens 14q32.33 polymorphism IgG CG3 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLADRB1*04:01, *04:08, *16:01 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*03:01, *04:04, *11:04 Disease risk Negative
IL1A Homo sapiens 2q14.1 SNP rs1800587 N/A Negative
IL-1RN Homo sapiens 2q14.1 SNP rs 16944 N/A Negative
IL1B Homo sapiens 2q14.1 SNP rs 1143634 N/A Positive
IL1B Homo sapiens 2q14.1 SNP IL-1 RN variable number tandom repeat (VNTR) N/A Negative
CTLA4 Homo sapiens 2q33.2 polymorphism -1722 T C Disease risk Positive
CTLA4 Homo sapiens 2q33.2 polymorphism -1661 A G Disease risk Positive
CTLA4 Homo sapiens 2q33.2 polymorphism -318 C T Disease risk Positive
CTLA4 Homo sapiens 2q33.2 polymorphism +49 A G Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP TACA Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP TACG Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP TGCG Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP TGCA Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP TATA Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP CACA Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP TATG Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP TGCG Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP TGTG Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQB1*0302 Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1502 Phenotypic risk Positive
PLA2G7 Homo sapiens 6p12.3 polymorphism TT Phenotypic risk Negative
PLA2G7 Homo sapiens 6p12.3 polymorphism GT Phenotypic risk Negative
PLA2G7 Homo sapiens 6p12.3 polymorphism GG Phenotypic risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*15 Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 polymorphism DQAl*0102 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQB1*0201 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*O302 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0602 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQB1*0301 Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 polymorphism DQAl*0102 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0602 Disease risk Negative
MIR146A Homo sapiens 5q33.3 SNP rs57095329 Disease risk Negative
MIR146A Homo sapiens 5q33.3 SNP rs2910164 Disease risk Positive
MIR146A Homo sapiens 5q33.3 polymorphism rs2910164 G>C Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*04:05 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*15:01 Disease risk Positive
TGFB1 Homo sapiens 19q13.2 polymorphism N/A Disease risk Positive
TGFB2 Homo sapiens 1q41 polymorphism N/A Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQB1*0501 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQB1*0602 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQB1*0302 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism *0502-*0504 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism *0601 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism *0603-*0605 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism *02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism *0301 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism *0303 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism *0401-*0402 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1502 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*04 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *0101-*0102 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *1502 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *1601 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *0301 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *0401-*0408 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *11-*14 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *07-*08 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *0901 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism *1001 Disease risk Negative
SP140 Homo sapiens 2q37.1 SNP rs28445040 Disease risk Positive
CBLB Homo sapiens 3q13.11 SNP rs12487066 Disease risk Positive
CBLB Homo sapiens 3q13.11 SNP rs2028597 Disease risk Negative
CBLB Homo sapiens 3q13.11 SNP rs9657904 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135005 Disease risk Negative
APOE Homo sapiens 19q13.32 polymorphism E2 Disease risk Negative
APOE Homo sapiens 19q13.32 polymorphism E3 Disease risk Negative
APOE Homo sapiens 19q13.32 polymorphism E4 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0201 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0301 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0302 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0501 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0502 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0601 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphism DQBl*0602 Disease risk Negative
P2RX7 Homo sapiens 12q24.31 SNP rs17525809 Disease risk Positive
P2RX7 Homo sapiens 12q24.31 SNP rs208294 Disease risk Negative
P2RX7 Homo sapiens 12q24.31 SNP rs1718119 Disease risk Negative
P2RX7 Homo sapiens 12q24.31 polymorphism TA Disease risk Negative
P2RX7 Homo sapiens 12q24.31 polymorphism TG Disease risk Negative
P2RX7 Homo sapiens 12q24.31 polymorphism CG Disease risk Positive
P2RX7 Homo sapiens 12q24.31 polymorphism AACCTG Disease risk Positive
GRIK2 Homo sapiens 6q16.3 polymorphism GCGc Disease risk Negative
GRIK2 Homo sapiens 6q16.3 polymorphism CGGTGAT Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*15 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*04 Disease risk Positive
VDR Homo sapiens 12q13.11 polymorphism VDRG Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1501 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0501 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0201 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0202 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0301 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0401 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0402 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0501 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0601 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*0901 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*1301 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*1401 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*1701 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DPB1*1901 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0101 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1501 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1502 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1602 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0303 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0401 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0405 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0407 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0410 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1101 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1201 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1202 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1301 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1302 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1401 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1403 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1405 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1406 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0701 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0802 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0803 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*0901 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*1001 Disease risk Negative
RGS1 Homo sapiens 1q31.2 SNP rs2760524 Disease risk Negative
KIF21B Homo sapiens 1q32.1 SNP rs12122721 Disease risk Negative
TMEM39A Homo sapiens 3q13.33 SNP rs1132200 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Negative
CLEC16A Homo sapiens 16p13.13 SNP rs12708716 Disease risk Negative
CLEC16A Homo sapiens 16p13.13 SNP rs6498169 Disease risk Negative
IRF8 Homo sapiens 16q24.1 SNP rs17445836 Disease risk Negative
CD226 Homo sapiens 18q22.2 SNP rs763361 Disease risk Negative
TYK2 Homo sapiens 19p13.2 SNP rs34536443 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 SNP rs2394160 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 SNP rs2854050 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 SNP rs3830041 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 SNP rs3129939 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 SNP rs9271366 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 SNP rs2187668 Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 SNP rs9277535 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism DRB1*15 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 polymorphism position 318 of the CTLA4 promoter Disease risk Positive
CTLA4 Homo sapiens 2q33.2 polymorphism position 49 in exon 1 Disease risk Positive
TNF Homo sapiens 6p21.33 polymorphism TNF*(-308)A Disease risk Positive
IFNG Homo sapiens 12q15 polymorphism TNF*(-308)A Disease risk Negative
IL6 Homo sapiens 7p15.3 polymorphism TNF*(-308)A Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DR2(+), DC 2.2(+) Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism DR2(+), DC 2.2(-) Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*15:01 Disease risk Positive
HLA-A Homo sapiens 6p22.1 polymorphism HLA-A*02:01 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphism HLA-B*38:01 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphism HLA-B*44:02 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphism rs9277565 (T)d Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*03:01 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphism HLA-B*55:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*13:03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DRB1*08:01 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10R2 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10R3 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10R4 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G7 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G8 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G9 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G10 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G11 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G12 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G13 Disease risk Negative
IL10 Homo sapiens 1q32.1 polymorphism IL-10G14 Disease risk Positive
IL10 Homo sapiens 1q32.1 polymorphism IL-10G15 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*010 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0201 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0202 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0301 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0302 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0303 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0402 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0501 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0502 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0503 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0601 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0602 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0603 Treatment risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0604 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0101 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0102 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0103 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0104 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0201 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0301 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0303 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0401 Treatment risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0501 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*10 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16 Disease risk Negative
FasL Homo sapiens 1q24.3 allel A Disease risk Negative
FasL Homo sapiens 1q24.3 allel B Disease risk Positive
IGH Homo sapiens 14q32.33 SNP rs11621145 Disease risk Positive
MEFV Homo sapiens 16p13.3 mutation E148Q Disease risk Positive
MEFV Homo sapiens 16p13.3 mutation K695R Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphisms (-308) Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphisms (-238) Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphisms (-857) Disease risk Positive
PTPRC Homo sapiens 1q31.3-q32.1 mutation C->G mutation in position 77 of exon 4 Disease risk Positive
TRB Homo sapiens 7q34 rearrangement N/A Disease risk Positive
SPON1 Homo sapiens 11p15.2 SNP rs7104613T Phenotypic risk Positive
SEMA3A Homo sapiens 7q21.11 SNP rs740948A Phenotypic risk Positive
MBP Homo sapiens 18q23 allel A Disease risk Positive
MBP Homo sapiens 18q23 allel B Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs6074022 Disease risk Negative
TNF Homo sapiens 6p21.33 allel A Disease risk Positive
VDR Homo sapiens 12q13.11 polymorphisms C_3290614_10(A/T) Disease risk Negative
VDR Homo sapiens 12q13.11 polymorphisms C_8716062_10(C/T) Disease risk Negative
VDR Homo sapiens 12q13.11 polymorphisms C_12060044_1_(A/G) Disease risk Negative
VDR Homo sapiens 12q13.11 polymorphisms C_2880811_10(C/T) Disease risk Negative
NOS2 Homo sapiens 17q11.2 genotype n/n Disease risk Negative
NOS2 Homo sapiens 17q11.2 genotype n/i Disease risk Negative
NOS2 Homo sapiens 17q11.2 genotype i/i Disease risk Negative
NOS2 Homo sapiens 17q11.2 allel n Disease risk Negative
NOS2 Homo sapiens 17q11.2 allel i Disease risk Negative
IL1RN Homo sapiens 2q14.1 polymorphisms A1/A1 Phenotypic risk Positive
IL1RN Homo sapiens 2q14.1 polymorphisms A1/A2 Phenotypic risk Positive
IL1RN Homo sapiens 2q14.1 polymorphisms A2/A2 Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*010 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1502 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1503 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR2 Disease risk Positive
IL1B Homo sapiens 2q14.1 polymorphisms (-511 C/T) Disease risk Negative
IL2 Homo sapiens 4q27 polymorphisms (-475 A/T) Disease risk Negative
IL2 Homo sapiens 4q27 polymorphisms (-631 G/A) Disease risk Negative
IL6 Homo sapiens 7p15.3 polymorphisms (-634 C/G) Disease risk Positive
PON1 Homo sapiens 7q21.3 polymorphisms (M55L) Disease risk Negative
PON1 Homo sapiens 7q21.3 polymorphisms (Q192R) Disease risk Positive
UCP2 Homo sapiens 11q13.4 polymorphisms (-866 G/A) Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR2 Disease risk Negative
IL1B Homo sapiens 2q14.1 polymorphisms (-511 C/T) Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphisms (-308 A/G) Disease risk Positive
APOA1 Homo sapiens 11q23.3 allel A Phenotypic risk Positive
APOA1 Homo sapiens 11q23.3 polymorphisms APOA1 –75G/A Phenotypic risk Positive
LRP2 Homo sapiens 2q31.1 allel rs12988804*T Phenotypic risk Positive
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6195(AA) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6195(AG) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 allel rs6195(A) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 allel rs6195(G) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6196(TT) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6196(TC) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6196(CC) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 allel rs6196(T) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 allel rs6196(C) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6188(GG) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6188(GT) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphisms rs6188(TT) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 allel rs6188(G) Phenotypic risk Negative
NR3C1 Homo sapiens 5q31.3 allel rs6188(T) Phenotypic risk Negative
ATG5 Homo sapiens 6q21 polymorphisms rs2245214(GG/GC/CC) Disease risk Negative
ATG5 Homo sapiens 6q21 allel rs2245214(C/G) Disease risk Negative
ATG5 Homo sapiens 6q21 polymorphisms rs548234(TT/CC/TC) Disease risk Negative
ATG5 Homo sapiens 6q21 allel rs548234(T/C) Disease risk Negative
ATG5 Homo sapiens 6q21 polymorphisms rs573775(TT/TC/CC) Disease risk Negative
ATG5 Homo sapiens 6q21 allel rs573775(T/C) Disease risk Negative
ATG5 Homo sapiens 6q21 polymorphisms rs6568431(AA/AC/CC) Disease risk Negative
ATG5 Homo sapiens 6q21 allel rs6568431(A/C) Disease risk Negative
ATG5 Homo sapiens 6q21 polymorphisms rs6937876(GG/GA/AA) Disease risk Negative
ATG5 Homo sapiens 6q21 allel rs6937876(G/A) Disease risk Negative
ATG5 Homo sapiens 6q21 polymorphisms DRB1*01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*010 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*04 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*05 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*04-03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*03-02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*07-02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*03-06 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*15-06 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*01-05 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*03-03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*11-03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*04-03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*03-02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*07-02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*03-06 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*15-06 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*01-05 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*03-03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DR-DQ*11-03 Disease risk Negative
LTA Homo sapiens 6p21.33 polymorphisms TNF-b*1 Disease risk Negative
LTA Homo sapiens 6p21.33 polymorphisms TNF-b*2 Disease risk Positive
LTA Homo sapiens 6p21.33 polymorphisms TNF-b*1/*1 Disease risk Negative
LTA Homo sapiens 6p21.33 polymorphisms TNF-b*1/*2 Disease risk Negative
LTA Homo sapiens 6p21.33 polymorphisms TNF-b*2/*2 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1502 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1602 Disease risk Negative
HLA-DRB5 Homo sapiens 6p21.32 polymorphisms DRB5*0101 Disease risk Negative
HLA-DRB5 Homo sapiens 6p21.32 polymorphisms DRB5*0102 Disease risk Negative
HLA-DRB5 Homo sapiens 6p21.32 polymorphisms DRB5*new Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0101 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0102 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0103 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0501 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0502 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0601 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0602 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0603 Disease risk Negative
IL-1RL1 Homo sapiens 2q12.1 SNP rs10204137 Disease risk Positive
IL33 Homo sapiens 9p24.1 SNP rs1342326(TT) Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphisms TNFa9 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15(2) Disease risk Positive
CCR5 Homo sapiens 3p21.31 genotype (CCR5d32,DRB1*04) Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 genotype (CCR5d32,DRB1*04) Disease risk Positive
TGFB1 Homo sapiens 19q13.2 genotype (-509 TGFb1*C, DRB1*18(3),CTLA4*G) Disease risk Positive
CTLA4 Homo sapiens 2q33.2 genotype (-509 TGFb1*C, DRB1*18(3),CTLA4*G) Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 genotype (-509 TGFb1*C, DRB1*18(3),CTLA4*G) Disease risk Positive
LTA Homo sapiens 6p21.33 genotype (-238TNF*B1, -308TNF*A2,CTLA4*G) Disease risk Positive
TNF Homo sapiens 6p21.33 genotype (-238TNF*B1, -308TNF*A2,CTLA4*G) Disease risk Positive
CTLA4 Homo sapiens 2q33.2 genotype (-238TNF*B1, -308TNF*A2,CTLA4*G) Disease risk Positive
TNF Homo sapiens 6p21.33 allel rs1799964/C Phenotypic risk Positive
LTA Homo sapiens 6p21.33 allel rs769178/T Phenotypic risk Positive
VDR Homo sapiens 12q13.11 allel rs2189480/T Phenotypic risk Positive
VDR Homo sapiens 12q13.11 allel rs3782905/C Phenotypic risk Positive
MBP Homo sapiens 18q23 allel rs4890785/T Phenotypic risk Positive
APOE Homo sapiens 19q13.32 allel rs7412/T Phenotypic risk Positive
VDR Homo sapiens 12q13.11 allel rs1540339/T Phenotypic risk Positive
VDR Homo sapiens 12q13.11 allel rs2239186/G Phenotypic risk Positive
VDR Homo sapiens 12q13.11 allel rs2238136/T Phenotypic risk Positive
MBP Homo sapiens 18q23 allel rs8096433/A Phenotypic risk Positive
MBP Homo sapiens 18q23 allel rs17660901/G Phenotypic risk Positive
VDR Homo sapiens 12q13.11 allel rs2189480/T Phenotypic risk Positive
MBP Homo sapiens 18q23 allel rs8096433/A Phenotypic risk Positive
IL7R Homo sapiens 5p13.2 allel rs6897932/A Phenotypic risk Negative
TNF Homo sapiens 6p21.33 allel rs800629/A Phenotypic risk Negative
TNF Homo sapiens 6p21.33 allel rs3093671/A Phenotypic risk Negative
LTA Homo sapiens 6p21.33 allel rs769177/T Phenotypic risk Negative
LTA Homo sapiens 6p21.33 allel rs909253/A Phenotypic risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allel rs3135388/T Phenotypic risk Negative
TRB Homo sapiens 7q34 allel rs17133575/G Phenotypic risk Negative
TRB Homo sapiens 7q34 allel rs17243/G Phenotypic risk Negative
IL2RA Homo sapiens 10p15.1 allel rs2104286/C Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs7975128/A Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs2248098/A Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs2239182/T Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs2107301/A Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs2239179/C Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs3819545/G Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs2228570/T Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs2254210/A Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs2853564/G Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs4760648/T Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs11168287/G Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs4328262/G Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs4237855/G Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs7136534/T Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs7299460/A Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs4760658/G Phenotypic risk Negative
VDR Homo sapiens 12q13.11 allel rs4516035/C Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs17026/C Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs470724/T Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs470550/T Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs9676113/G Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs11661054/A Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs11661755/A Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs9675994/T Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs8090438/T Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs8094402/G Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs12456341/G Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs17576751/T Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs3794848/A Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs4890875/G Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs595997/G Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs2974260/T Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs2051344/A Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs470681/C Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs12967023/A Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs4890788/T Phenotypic risk Negative
MBP Homo sapiens 18q23 allel rs7232502/A Phenotypic risk Negative
APOE Homo sapiens 19q13.32 allel rs429358/C Phenotypic risk Negative
APOE Homo sapiens 19q13.32 allel rs7412/T Phenotypic risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1*1501-DQA1*0102-DQB1* 0602 (DR15) Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 genotype DRB1*1501-DQA1*0102-DQB1* 0602 (DR15) Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 genotype DRB1*1501-DQA1*0102-DQB1* 0602 (DR15) Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1*1501-DQA1*0102-DQB1* 0602 (DR15) Phenotypic risk Negative
HLA-DQA1 Homo sapiens 6p21.32 genotype DRB1*1501-DQA1*0102-DQB1* 0602 (DR15) Phenotypic risk Negative
HLA-DQB1 Homo sapiens 6p21.32 genotype DRB1*1501-DQA1*0102-DQB1* 0602 (DR15) Phenotypic risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1*15 + TGFB1*T + CCR5*d Disease risk Positive
TGFB1 Homo sapiens 19q13.2 genotype DRB1*15 + TGFB1*T + CCR5*d Disease risk Positive
CCR5 Homo sapiens 3p21.31 genotype DRB1*15 + TGFB1*T + CCR5*d Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1*15 + TGFB1*T + CCR5*d + IFNAR1*G Disease risk Positive
TGFB1 Homo sapiens 19q13.2 genotype DRB1*15 + TGFB1*T + CCR5*d + IFNAR1*G Disease risk Positive
CCR5 Homo sapiens 3p21.31 genotype DRB1*15 + TGFB1*T + CCR5*d + IFNAR1*G Disease risk Positive
IFNAR1 Homo sapiens 21q22.11 genotype DRB1*15 + TGFB1*T + CCR5*d + IFNAR1*G Disease risk Positive
TNF Homo sapiens 6p21.33 polymorphisms Chr 6p21 Disease risk Positive
TNF Homo sapiens 6p21.33 polymorphisms Chr 3q13 Disease risk Positive
TNF Homo sapiens 6p21.33 polymorphisms Chr 2q14 Phenotypic risk Positive
TNF Homo sapiens 6p21.33 polymorphisms Chr 19p13 Phenotypic risk Positive
TNF Homo sapiens 6p21.33 polymorphisms Chr 4p16 Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*010 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15 Phenotypic risk Negative
ERVW-1 Homo sapiens 7q21.2 CNV MSRV Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*010 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*17 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0102 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0602 Disease risk Negative
KIF5A Homo sapiens 12q13.3 SNP rs1678542 N/A Positive
KIF5A Homo sapiens 12q13.3 SNP rs2888334 N/A Positive
KIF5A Homo sapiens 12q13.3 SNP rs775249 N/A Negative
KIF5A Homo sapiens 12q13.3 SNP rs1678536 N/A Positive
KIF5A Homo sapiens 12q13.3 SNP rs7313599 N/A Positive
PIP4K2C Homo sapiens 12q13.3 SNP rs1078109 N/A Negative
ARHGEF25 Homo sapiens 12q13.3 SNP rs7305391 N/A Negative
ARHGEF25 Homo sapiens 12q13.3 SNP rs1564374 N/A Positive
OS9 Homo sapiens 12q13.3-q14.1 SNP rs3825078 N/A Positive
OS9 Homo sapiens 12q13.3-q14.1 SNP rs701006 N/A Positive
AGAP2 Homo sapiens 12q14.1 SNP rs2301551 N/A Negative
AGAP2 Homo sapiens 12q14.1 SNP rs12307841 N/A Negative
AGAP2 Homo sapiens 12q14.1 SNP rs12368653 N/A Positive
MARCHF9 Homo sapiens 12q14.1 SNP rs1048691 N/A Negative
TSFM Homo sapiens 12q14.1 SNP rs6581155 N/A Positive
SELP Homo sapiens 1q24.2 SNP rs6133 Disease risk Negative
SELL Homo sapiens 1q24.2 SNP rs4987310 Disease risk Negative
SELE Homo sapiens 1q24.2 SNP rs5368 Disease risk Negative
CD24 Homo sapiens 6q21 allele CD24 V/V Disease risk Positive
MCAT Homo sapiens 22q13.2 allele K* Disease risk Positive
MCAT Homo sapiens 22q13.2 allele J* Disease risk Negative
IL-12B Homo sapiens 5q33.3 SNP rs3212227 Disease risk Negative
IL-23R Homo sapiens 1p31.3 SNP rs2201841 Disease risk Negative
IL-23R Homo sapiens 1p31.3 SNP rs10889677 Disease risk Negative
IL-23R Homo sapiens 1p31.3 SNP rs7517847 Disease risk Negative
APOE Homo sapiens 19q13.32 DNA methylation N/A N/A Positive
ACKR3 Homo sapiens 2q37.3 DNA methylation N/A N/A Positive
GSTP1 Homo sapiens 11q13.2 allele lle Disease risk Negative
GSTP1 Homo sapiens 11q13.2 allele Val Disease risk Negative
OGG1 Homo sapiens 3p25.3 allele Ser Disease risk Positive
OGG1 Homo sapiens 3p25.3 allele Cys Disease risk Negative
XRCC1 Homo sapiens 19q13.31 allele Arg Disease risk Negative
XRCC1 Homo sapiens 19q13.31 allele Gln Disease risk Negative
GSTP1 Homo sapiens 11q13.2 genotype Ile/Ile Disease risk Negative
GSTP1 Homo sapiens 11q13.2 genotype Ile/Val Disease risk Negative
GSTP1 Homo sapiens 11q13.2 genotype Val/Val Disease risk Negative
GSTP1 Homo sapiens 11q13.2 genotype Ile/Val +Val/Val Disease risk Negative
OGG1 Homo sapiens 3p25.3 genotype Ser/Ser Disease risk Negative
OGG1 Homo sapiens 3p25.3 genotype Ser/Cys Disease risk Positive
OGG1 Homo sapiens 3p25.3 genotype Cys/Cys Disease risk Positive
OGG1 Homo sapiens 3p25.3 genotype Ser/Cys + Cys/Cys Disease risk Negative
XRCC1 Homo sapiens 19q13.31 genotype Arg/Arg Disease risk Negative
XRCC1 Homo sapiens 19q13.31 genotype Arg/Gln Disease risk Negative
XRCC1 Homo sapiens 19q13.31 genotype Gln/Gln Disease risk Negative
XRCC1 Homo sapiens 19q13.31 genotype Arg/Gln + Gln/Gln Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB10501 Phenotypic risk Positive
TAP1 Homo sapiens 6p21.32 allele Ile Disease risk Negative
TAP1 Homo sapiens 6p21.32 allele Val Disease risk Negative
TAP1 Homo sapiens 6p21.32 allele Asp Disease risk Negative
TAP1 Homo sapiens 6p21.32 allele Gly Disease risk Negative
TAP1 Homo sapiens 6p21.32 genotype Ile/Ile Disease risk Negative
TAP1 Homo sapiens 6p21.32 genotype Ile/Val Disease risk Negative
TAP1 Homo sapiens 6p21.32 genotype Val/Val Disease risk Negative
TAP2 Homo sapiens 6p21.32 allele Ile Disease risk Negative
TAP2 Homo sapiens 6p21.32 allele Val Disease risk Negative
TAP2 Homo sapiens 6p21.32 allele Asp Disease risk Negative
TAP2 Homo sapiens 6p21.32 allele Gly Disease risk Negative
TAP2 Homo sapiens 6p21.32 genotype Ile/Ile Disease risk Negative
TAP2 Homo sapiens 6p21.32 genotype Ile/Val Disease risk Negative
TAP2 Homo sapiens 6p21.32 genotype Val/Val Disease risk Negative
CNR1 Homo sapiens 6q15 SNP RS1049353(GG/GA/AA) Disease risk Negative
CNR1 Homo sapiens 6q15 SNP RS806377(GG/GA/AA) Disease risk Negative
CNR1 Homo sapiens 6q15 SNP RS806380(TT/TC/CC) Disease risk Negative
KLRB1 Homo sapiens 12p13.31 SNP rs4763655 Disease risk Positive
GSTT1 Homo sapiens 22q11.23 genotype M1/T1 Disease risk Positive
GSTM1 Homo sapiens 1p13.3 genotype M1/T1 Disease risk Positive
GSTT1 Homo sapiens 22q11.23 genotype M1/T1 Phenotypic risk Positive
GSTM1 Homo sapiens 1p13.3 genotype M1/T1 Phenotypic risk Positive
GSTT1 Homo sapiens 22q11.23 genotype M1/T1 Phenotypic risk Negative
GSTM1 Homo sapiens 1p13.3 genotype M1/T1 Phenotypic risk Negative
ARHGAP45 Homo sapiens 19p13.3 polymorphisms HA-1 1500/504(CA,CA/TG,TG) Disease risk Negative
ARHGAP45 Homo sapiens 19p13.3 polymorphisms HA-1 865(T,T/A,A) Disease risk Negative
ARHGAP45 Homo sapiens 19p13.3 polymorphisms HA-1 1403(G,G/A,A) Disease risk Negative
ABCA7 Homo sapiens 19p13.3 polymorphisms ABCA7 955(A, A/G, G) Disease risk Negative
ABCA7 Homo sapiens 19p13.3 polymorphisms ABCA7 4580(C, C/G, G) Disease risk Negative
CIITA Homo sapiens 16p13.13 SNP rs3087456 Disease risk Negative
CIITA Homo sapiens 16p13.13 SNP rs4774 Disease risk Positive
PTPN22 Homo sapiens 1p13.2 polymorphisms 620W Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms E148Q Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms P369S Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms F479L Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms M680I (G/C) Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms I692 DEL Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms M694V Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms M694I Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms K695R Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms V726A Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms A744S Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms R761H Phenotypic risk Negative
MEFV Homo sapiens 16p13.3 polymorphisms M680I (G/A) Phenotypic risk Negative
HPRT1 Homo sapiens Xq26.2-q26.3 mutant frequency N/A Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15:01 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15:02 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14:04 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*10:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08:03:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07:01:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04:03:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04:01:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03:01:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01:01:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*02:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*03:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*03:02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*03:03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*04:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*05:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06:02 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06:09 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×01:01-DQB1×05:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×03:01-DQB1×02:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×04:03-DQB1×03:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×07:01-DQB1×02:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×07:01-DQB1×03:03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×08:03-DQB1×03:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×10:01-DQB1×05:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×11:01-DQB1×03:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×13:02-DQB1×06:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×13:01-DQB1×06:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×14:04-DQB1×05:03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×15:01 a-DQB1×05:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1×15:01a-DQB1×06:02 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932(CC) Disease risk Positive
PTPN22 Homo sapiens 1p13.2 SNP 1858 SNP Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs155141 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs1449263 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs3770138 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs3770136 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs3770132 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs155106 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs1038034 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs2305586 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs3770115 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs3816521 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs3770111 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs6714061 Disease risk Negative
ITGA4 Homo sapiens 2q31.3 SNP Rs4667319 Disease risk Negative
SCN10A Homo sapiens 3p22.2 SNP rs6801957 Phenotypic risk Positive
SCN10A Homo sapiens 3p22.2 SNP rs6795970 Phenotypic risk Positive
CYBB Homo sapiens Xp21.1-p11.4 SNP rs72619425 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15:01 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03:01 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04:05 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*15:03 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*04:01:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*16:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*14:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*09:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*08:04 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*11:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*07:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13:03 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*03:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*10:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*13:02 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*12:01 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*01:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*02e Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*03:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*03:02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*03:03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*04:02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*05:01 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*05:02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*05:03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06:02 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06:03 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06:04 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*06:09 Disease risk Negative
ST8SIA1 Homo sapiens 12p12.1 SNP rs704219 Disease risk Negative
ST8SIA1 Homo sapiens 12p12.1 SNP rs2041906 Disease risk Negative
ST8SIA1 Homo sapiens 12p12.1 SNP rs1558793 Disease risk Negative
ST8SIA1 Homo sapiens 12p12.1 SNP rs4762896 Disease risk Negative
CD40 Homo sapiens 20q13.12 SNP rs4810485*T Disease risk Positive
CD86 Homo sapiens 3q13.33 SNP rs9282641*G Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs4810485*T Disease risk Positive
GAL Homo sapiens 11q13.2 allele rs948854(G) Disease risk Positive
GAL Homo sapiens 11q13.2 allele rs948854(G) Phenotypic risk Positive
GAL Homo sapiens 11q13.2 SNP rs948854 Phenotypic risk Positive
PRNP Homo sapiens 20p13 SNP Prnp129 M/V Disease risk Negative
PRNP Homo sapiens 20p13 SNP Prnp129 M/V Disease risk Negative
VEGFA Homo sapiens 6p21.1 genotype rs1413711(T/T) Disease risk Positive
VEGFA Homo sapiens 6p21.1 genotype rs1413711(T/C) Disease risk Positive
VEGFA Homo sapiens 6p21.1 genotype rs1413711(C/C) Disease risk Positive
TIMP3 Homo sapiens 22q12.3 genotype rs9621532(A/A) Disease risk Negative
TIMP3 Homo sapiens 22q12.3 genotype rs9621532(C/C) Disease risk Negative
TIMP3 Homo sapiens 22q12.3 genotype rs9621532(A/C) Disease risk Negative
IL6 Homo sapiens 7p15.3 genotype rs1800796(C/G) Disease risk Negative
IL6 Homo sapiens 7p15.3 genotype rs1800796(G/G) Disease risk Negative
IL6 Homo sapiens 7p15.3 genotype rs1800796(C/C) Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0101 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0102 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0103 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0301 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0401 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0402 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0403 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0404 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0405 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0407 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0701 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0801 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0901 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1001 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1101 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1103 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1104 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1201 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1301 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1302 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1303 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1401 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1502 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1601 Disease risk Negative
MTHFR Homo sapiens 1p36.22 missense C677T Disease risk Negative
MTHFR Homo sapiens 1p36.22 missense A1298C Disease risk Positive
SPP1 Homo sapiens 4q22.1 polymorphisms 5891C/T Phenotypic risk Positive
SPP1 Homo sapiens 4q22.1 polymorphisms 7052T/C Phenotypic risk Negative
SPP1 Homo sapiens 4q22.1 polymorphisms 1687A/G Phenotypic risk Negative
SPP1 Homo sapiens 4q22.1 polymorphisms 381T/C Phenotypic risk Negative
SPP1 Homo sapiens 4q22.1 polymorphisms 94 deletion/G Phenotypic risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0101 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0102 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0103 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1502 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1601 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1602 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0301 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0303 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0401 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0402 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0403 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0404 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0405 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0406 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0407 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0408 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1101 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1102 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1103 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1104 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1201 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1301 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1302 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1303 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1305 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1405 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1402 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0701 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0801 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0804 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*0901 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1001 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0101 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0102 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0103 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0104 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0201 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0301 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0302 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0303 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0401 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0501 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0503 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0501 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0502 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0503 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0609 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0602 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0603 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0604 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0605 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0606 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0201 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0301 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0302 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0303 Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0402 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DRB1*1501 Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 polymorphisms DQA1*0201 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 polymorphisms DQB1*0602 Disease risk Positive
HLA-DPA1 Homo sapiens 6p21.32 polymorphisms DPA1*0103 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphisms DPB1*04 Disease risk Negative
ERVW-1 Homo sapiens 7q21.2 CNV N/A Disease risk Positive
NFASC Homo sapiens 1q32.1 SNP rs12368653 Disease risk Positive
NFASC Homo sapiens 1q32.1 SNP rs703842 Disease risk Positive
PDLIM7 Homo sapiens 5q35.3 genotype N/A Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw1 Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw2 Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw3 Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw4 Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw5 Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw6 Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw7 Disease risk Negative
HLA-C Homo sapiens N/A polymorphisms Cw8 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR1 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR2 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR3 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR4 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR5 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR6 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms DR7 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A1 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A2 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A3 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A11 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A23 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A24 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A25 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A26 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A28 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A29 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A30+31 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms A32 Disease risk Negative
HLA-A Homo sapiens 6p22.1 polymorphisms Aw33 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B5 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B7 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B8 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B12 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B13 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B14 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B15 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B17 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B18 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B21 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms Bw22 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B27 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B35 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B37 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B38 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B39 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B40 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B41 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms B47 Disease risk Negative
HLA-B Homo sapiens 6p21.33 polymorphisms Bw53 Disease risk Negative
IGH Homo sapiens 14q32.33 rearrangement N/A Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs12722495 Phenotypic risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Phenotypic risk Positive
TRIM5 Homo sapiens 11p15.4 SNP rs3802981 Disease risk Positive
HERV-Fc1 Homo sapiens Xq21.33 SNP rs391745 Disease risk Positive
FAS Homo sapiens 10q23.31 SNP rs2234767 Disease risk Positive
DDT Homo sapiens 22q11.23 SNP rs755622 Disease risk Positive
CBLB Homo sapiens 3q13.11 SNP rs9657904 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
IL4 Homo sapiens 5q31.1 allele variable number of tandem repeat polymorphism Disease risk Positive
TRB Homo sapiens 7q34 allele Vβ1I（25kb） Disease risk Positive
TRB Homo sapiens 7q34 allele Cβ Disease risk Positive
TRB Homo sapiens 7q34 allele Vβ1I Disease risk Positive
HLA-A Homo sapiens 6p22.1 allele HLA-A3 Disease risk Positive
HLA-B Homo sapiens 6p21.33 allele HLA-B7 Disease risk Positive
IL10 Homo sapiens 1q32.1 N/A IL-10G7-11 Disease risk Negative
IL10 Homo sapiens 1q32.1 allele IL-10G13-15 Disease risk Negative
IL10 Homo sapiens 1q32.1 allele IL-10G12 Disease risk Positive
IL10 Homo sapiens 1q32.1 allele IL-10R2-4 Disease risk Negative
HAVCR2 Homo sapiens 5q33.3 SNP rs10515746 Disease risk Positive
HAVCR2 Homo sapiens 5q33.3 SNP rs10053538 Disease risk Positive
IL21 Homo sapiens 4q27 SNP rs2221903 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs2055979 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs2055979 Phenotypic risk Positive
IL16 Homo sapiens 15q25.1 SNP rs4072111 Disease risk Positive
IL16 Homo sapiens 15q25.1 SNP rs11556218 Disease risk Positive
NINJ2 Homo sapiens 12p13.33 SNP rs7298096 Treatment risk Positive
SLC6A4 Homo sapiens 17q11.2 polymorphisms 5-HTTLPR, rs35521, and STin2VNTR Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Negative
IL25 Homo sapiens 14q11.2 polymorphisms c424C/A Disease risk Negative
POLG Homo sapiens 15q26.1 POLG CAG repeat length N/A Disease risk Negative
MMP9 Homo sapiens 20q13.12 polymorphisms 1562 C/T Disease risk Positive
TBX21 Homo sapiens 17q21.32 polymorphisms 1514T > C Disease risk Positive
CD6 Homo sapiens 11q12.2 SNP rs17824933 Disease risk Positive
TMEM39A Homo sapiens 3q13.33 SNP rs1132200 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
IL10 Homo sapiens 1q32.1 SNP rs1800871, rs1800872, and rs1800896 Disease risk Negative
NOS3 Homo sapiens 7q36.1 SNP rs2070744 Disease risk Positive
NOS3 Homo sapiens 7q36.1 SNP rs1799983 Disease risk Positive
FOXP3 Homo sapiens Xp11.23 SNP rs3761547, rs3761548 Disease risk Negative
GATA3 Homo sapiens 10p14 SNP rs3824662 Disease risk Negative
PDCD1 Homo sapiens 2q37.3 SNP rs36084323 Disease risk Negative
PDCD1 Homo sapiens 2q37.3 SNP rs11568821 Disease risk Positive
PDCD1 Homo sapiens 2q37.3 SNP rs2227981 Disease risk Positive
AQP4 Homo sapiens 18q11.2 SNP rs16942851, rs1058424, rs335929, rs335931, rs162007, rs3763043 Disease risk Negative
CCR5 Homo sapiens 3p21.31 allele Δ32 Disease risk Negative
IL1A Homo sapiens 2q14.1 SNP rs1800587 Disease risk Negative
IL1B Homo sapiens 2q14.1 SNP rs16944 Disease risk Positive
IL1B Homo sapiens 2q14.1 SNP rs1143634 Disease risk Negative
IL1R1 Homo sapiens 2q11.2-q12.1 SNP rs2234650 Disease risk Positive
IL1RN Homo sapiens 2q14.1 SNP rs315952 Disease risk Positive
FOXP3 Homo sapiens Xp11.23 SNP rs2232369 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2225870 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs1544410 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk Positive
FCRL5 Homo sapiens 1q23.1 SNP rs2012199 Disease risk Positive
FCRL5 Homo sapiens 1q23.1 SNP rs6679793 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs7718919 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs11567685 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
HSPA1A Homo sapiens 6p21.33 SNP rs1061581 Disease risk Negative
IL7 Homo sapiens 8q21.13 SNP rs1520333 Disease risk Positive
AIRE Homo sapiens 21q22.3 SNP rs1800520 Disease risk Positive
MMP9 Homo sapiens 20q13.12 polymorphisms MMP-9 -1562 C/T Disease risk Positive
MMP9 Homo sapiens 20q13.12 polymorphisms MMP-9 -1562 C/T Disease risk Positive
CD226 Homo sapiens 18q22.2 SNP rs763361 Disease risk Negative
DNMT3B Homo sapiens 20q11.21 SNP rs1569686 Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphisms N/A Disease risk Positive
HFE Homo sapiens 6p22.2 polymorphisms C282Y Disease risk Negative
HFE Homo sapiens 6p22.2 polymorphisms H63D Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 polymorphisms from DR1 to DR18 Disease risk Positive
MMP9 Homo sapiens 20q13.12 SNP rs3918242 Disease risk Positive
IFNG Homo sapiens 12q15 polymorphisms at position +874 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP HLA-DRB1*15 allele(DRB1*01,DRB1*03,DRB1*04) Treatment risk Positive
IL10 Homo sapiens 1q32.1 SNP IL-10 -1082 G/G and IL-10 -819 C/C Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP HLA-DRB1*15 Disease risk Positive
APOE Homo sapiens 19q13.32 SNP SNP469,SNP457,SNP992,APOE,SNP952,SNP873,SNP888,SNP988 Disease risk Positive
PTPRC Homo sapiens 1q31.3-q32.1 SNP exon 4 (C→G nucleotide transition in position 77) Disease risk Positive
IFNG Homo sapiens 12q15 SNP IFN-γ intron III (+2118 site A/G and +3586 site G/ACT). Disease risk Positive
IKZF3 Homo sapiens 17q12-q21.1 SNP rs907091 Disease risk Positive
CD69 Homo sapiens 12p13.31 SNP rs11052877 Disease risk Negative
IQGAP1 Homo sapiens 15q26.1 SNP rs11609 Disease risk Positive
IL18 Homo sapiens 11q23.1 SNP IL-18 -137C/G and -607C/A Disease risk Positive
IL32 Homo sapiens 16p13.3 SNP rs45499297 Disease risk Positive
IL2 Homo sapiens 4q27 SNP 631 and 475 IL-2 promoter polymorphisms Disease risk Negative
MIF Homo sapiens 22q11.23 SNP rs755622 Disease risk Negative
FAS Homo sapiens 10q23.31 SNP a band at 189 bp (allele G) or a band at 233 bp (allele A) Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP HLA-DRB1*15+/- Disease risk Negative
HLA-A Homo sapiens 6p22.1 SNP HLA-A*02+/- Disease risk Negative
HLA-B Homo sapiens 6p21.33 SNP HLA-B*07+/- Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP Exon 10 C/T Disease risk Positive
NOS2 Homo sapiens 17q11.2 SNP two promoter region microsatellites, (CCTTT)n and (TAAA)n, the original exon 10 C/T SNP, and an additional SNP within exon16, C/T (S569L) Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP CTLA-4-318, CTLA-4+49 Disease risk Negative
CD28 Homo sapiens 2q33.2 SNP CD28-I3+17 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP HLA-DRB1*1501, DRB1*04, DQB1*02,DQB1*0302, DQB1*0602 Disease risk Positive
VDR Homo sapiens 12q13.11 polymorphisms N/A Disease risk Negative
DBP Homo sapiens 19q13.33 polymorphisms N/A Disease risk Negative
CYP27A1 Homo sapiens 2q35 polymorphisms N/A Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388 Disease risk Positive
DIPK1A Homo sapiens 1p22.1 SNP rs7536563 Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs725613, rs12708716 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286, rs35285258 Disease risk Positive
RPL5 Homo sapiens 1p22.1 SNP rs10735781 rs6680578 rs6604026 Disease risk Positive
KANK1 Homo sapiens 9p24.3 SNP rs10975200 Disease risk Positive
MBOAT2 Homo sapiens 2p25.1 SNP rs11109670 Disease risk Positive
TBC1D2 Homo sapiens 9q22.33 SNP rs16914086 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele *1501,*0301,*0701,*1104,*0102 Phenotypic risk Positive
C4A Homo sapiens 6p21.33 allele C4AQ0(null allele at the C4A locus) Disease risk Positive
NFKBIA Homo sapiens 14q13.2 SNP rs3138053 Disease risk Positive
NFKBIA Homo sapiens 14q13.2 SNP rs2233406 Disease risk Positive
NFKBIA Homo sapiens 14q13.2 SNP rs2233408 Disease risk Negative
IL6 Homo sapiens 7p15.3 allele A1,A2,A3,A4,A5,A6,A7,A8d,A9 Disease risk Negative
IL6 Homo sapiens 7p15.3 allele A1,A2,A3,A4,A5,A6,A7,A8d,A9 Phenotypic risk Positive
TRBV20OR9-2 Homo sapiens 9p13.3 allele N/A Disease risk Positive
TRBV20OR9-2 Homo sapiens 9p13.3 allele N/A Disease risk Positive
TNF Homo sapiens 6p21.33 allele TNFa allele,TNFb allele,TNFa, b combination Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs7041, rs4588 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs7041, rs4588 Disease risk Negative
DBP Homo sapiens 19q13.33 SNP rs7041, rs4588 Disease risk Positive
ERG Homo sapiens 21q22.2 polymorphism PvuII Disease risk Positive
ERG Homo sapiens 21q22.2 polymorphism Xba Disease risk Negative
CD24 Homo sapiens 6q21 SNP N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 haplotype HLA-DRB1*15:01 haplotype Disease risk Positive
VDR Homo sapiens 12q13.11 polymorphism TaqI, ApaI Disease risk Negative
STK11 Homo sapiens 19p13.3 SNP rs9282860 Disease risk Positive
APOE Homo sapiens 19q13.32 SNP N/A Phenotypic risk Positive
IL27 Homo sapiens 16p12.1-p11.2 polymorphism N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Phenotypic risk Positive
HLA-DPA1 Homo sapiens 6p21.32 polymorphism HLA-DPw4 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 polymorphism HLA-DR2 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP N/A Disease risk Negative
LILRA3 Homo sapiens 19q13.4 Deletion 6.7-kbp Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*1501 Disease risk Positive
PVR Homo sapiens 19q13.31 polymorphism N/A Disease risk Negative
APOE Homo sapiens 19q13.32 allele N/A Disease risk Negative
TARDBP Homo sapiens 1p36.22 mutation Ala382Thr Disease risk Negative
C9orf72 Homo sapiens 9p21.2 expansion N/A Disease risk Negative
IL7 Homo sapiens 8q21.13 SNP rs1520333 Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs1414273 Disease risk Negative
TNFRSF1A Homo sapiens 12p13.31 SNP rs1800693 Disease risk Negative
EVI5 Homo sapiens 1p22.1 SNP rs11808092 Disease risk Positive
MTHFR Homo sapiens 1p36.22 SNP rs1801131 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs9271366 Disease risk Positive
B2m Homo sapiens 2 E5; 2 60.55 cM Deletion class I-deficient (β2m/) Disease risk Positive
MBP Homo sapiens 18q23 DNA length polymorphism RraI, EcoR Disease risk Negative
TNFRSF6B Homo sapiens 20q13.33 SNP rs4809330(*)A Disease risk Positive
TNFRSF14 Homo sapiens 1p36.32 SNP rs6684865(*)A Disease risk Positive
MOG Homo sapiens 6p22.1 restriction fragment length polymorphism (RFLP) 1.9 kb Taq 1 Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP A49G Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs13188960 Disease risk Positive
LAG3 Homo sapiens 12p13.31 SNP rs2365095 Disease risk Positive
IGH Homo sapiens 14q32.33 CNV VH4-34 genecopy number Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 genotype DRB1*15 Phenotypic risk Positive
MC1R Homo sapiens 16q24.3 the red hair color (RHC) variant Arg151Cys, Arg160Trp, Asp294His Disease risk Positive
KLC1 Homo sapiens 14q32.33 SNP rs8702 Disease risk Positive
CCR5 Homo sapiens 3p21.31 Deletion Δ32 deletion allele Treatment risk Negative
CCR5 Homo sapiens 3p21.31 Deletion Δ32 deletion allele Phenotypic risk Positive
LAG3 Homo sapiens 12p13.31 SNP rs870849 Disease risk Negative
CD4 Homo sapiens 12p13.31 SNP rs1922452 Disease risk Negative
CD4 Homo sapiens 12p13.31 SNP rs951818 Disease risk Negative
IL1A Homo sapiens 2q14.1 polymorphism IL-1 α(-889 T/C) Disease risk Positive
IL1R1 Homo sapiens 2q11.2-q12.1 polymorphism IL-1R (pst1 1970 C/T) Disease risk Positive
TNF Homo sapiens 6p21.33 polymorphism TNFF-α (-308 G/A and -238G/A) Disease risk Positive
IL1B Homo sapiens 2q14.1 polymorphism IL-1β (-511 C/T and +3962 C/T) Disease risk Positive
IL1RN Homo sapiens 2q14.1 polymorphism IL-1Ra (mspal 11100 T/C) Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP 504 C (GCA haplotype) Disease risk Positive
EIF2B5 Homo sapiens 3q27.1 SNP rs843358 Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphism TNF-α 376 Disease risk Positive
TNF Homo sapiens 6p21.33 SNP rs1800629 Disease risk Positive
GSK3B Homo sapiens 3q13.33 SNP rs334558 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 polymorphism N/A Disease risk Negative
FTO Homo sapiens 16q12.2 SNP rs9939609 Disease risk Negative
FTO Homo sapiens 16q12.2 SNP rs9939609 Phenotypic risk Positive
GSTP1 Homo sapiens 11q13.2 polymorphism A313 G Disease risk Negative
NQO1 Homo sapiens 16q22.1 polymorphism C609 T Disease risk Positive
GSTP1 Homo sapiens 11q13.2 polymorphism A313 G Phenotypic risk Positive
MT-ND1 Homo sapiens N/A polymorphism Nt 4216 T>C Disease risk Positive
MT-ND2 Homo sapiens N/A polymorphism Nt 5153 A>G Disease risk Positive
MT-ND3 Homo sapiens N/A polymorphism Nt 10142 C>T Disease risk Positive
MT-ND4 Homo sapiens N/A polymorphism Nt 11353 T>C, Nt 11935 T>C, Nt 12062 C>T Disease risk Positive
MT-ND5 Homo sapiens N/A polymorphism Nt 13042 G>A, Nt 13708 G>A Disease risk Positive
MT-ND6 Homo sapiens N/A polymorphism Nt 14179 G>A Disease risk Positive
TRA Homo sapiens 14q11.2 polymorphism N/A Disease risk Negative
NR3C1 Homo sapiens 5q31.3 polymorphism N363S, ER22/23EK, BclIG Disease risk Positive
PRNP Homo sapiens 20p13 polymorphism 129Val Disease risk Negative
TLR3 Homo sapiens 4q35.1 polymorphism 1377 Disease risk Positive
TLR3 Homo sapiens 4q35.1 polymorphism TLR9-1486 Disease risk Negative
TLR3 Homo sapiens 4q35.1 polymorphism TLR9 2848 Disease risk Positive
IFIH1 Homo sapiens 2q24.2 SNP rs2111485, rs1990760, rs3747517, rs13023380 Disease risk Negative
RIGI Homo sapiens 9p21.1 SNP rs12555727, rs10813825, rs6476363, rs659527, rs626214 Disease risk Negative
DHX58 Homo sapiens 17q21.2 SNP rs2074158 Disease risk Negative
MAVS Homo sapiens 20p13 SNP rs4815617, rs7262903, rs17857295, rs45437096, rs16989000 Disease risk Negative
IGHV4-39 Homo sapiens 14q32.33 Deletion IGHV4-39 Disease risk Negative
APOE Homo sapiens 19q13.32 allele N/A Disease risk Positive
HAMP Homo sapiens 19q13.12 SNP rs10421768 Phenotypic risk Positive
TF Homo sapiens 3q22.1 SNP rs1049296 Phenotypic risk Positive
TF Homo sapiens 3q22.1 SNP rs3811647 Phenotypic risk Positive
TFR2 Homo sapiens 7q22.1 SNP rs7385804 Phenotypic risk Negative
IL7R Homo sapiens 5p13.2 haplotype Hap 1, Hap 2, Hap 4 Treatment risk Positive
CCR5 Homo sapiens 3p21.31 allele CCR5 Delta32 Disease risk Negative
CCR5 Homo sapiens 3p21.31 polymorphism promoter -2459 Disease risk Negative
CCR5 Homo sapiens 3p21.31 allele CCR5 Delta32 Treatment risk Negative
CCR5 Homo sapiens 3p21.31 polymorphism promoter -2459 Treatment risk Negative
IL17A Homo sapiens 6p12.2 SNP rs2275913 Disease risk Negative
IL17F Homo sapiens 6p12.2 SNP rs763780 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DRB1*0301 Disease risk Positive
HLA-B Homo sapiens 6p21.33 allele HLA-B*52 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs2228570 (Fok1) Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs731236 (Taq1) Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Phenotypic risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Phenotypic risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs7090512 Phenotypic risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
TNF Homo sapiens 6p21.33 polymorphism TNF-α -308 Disease risk Negative
LTA Homo sapiens 6p21.33 allele TNF-β +252 Disease risk Negative
IL4 Homo sapiens 5q31.1 allele IL-4 (-590) Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele DRB11501 Disease risk Positive
GFI1 Homo sapiens 1p22.1 SNP rs11804321 Disease risk Positive
CIITA Homo sapiens 16p13.13 haplotype 168A→G Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DRB1*15 Disease risk Negative
CD86 Homo sapiens 3q13.33 SNP rs928264 Disease risk Negative
PTAFR Homo sapiens 1p35.3 polymorphism A224D Disease risk Positive
GAS5 Homo sapiens 1q25.1 SNP rs2067079 Disease risk Positive
GAS5 Homo sapiens 1q25.1 SNP rs6790 Disease risk Negative
CBLB Homo sapiens 3q13.11 SNP rs12487066 Treatment risk Negative
GRIA3 Homo sapiens Xq25 SNP rs12557782 Treatment risk Positive
CTSS Homo sapiens 1q21.3 SNP rs1136774 Treatment risk Positive
OAS1 Homo sapiens 12q24.13 SNP rs10774671 Treatment risk Negative
TNFRSF10A Homo sapiens 8p21.3 SNP rs20576 Treatment risk Negative
IFI16 Homo sapiens 1q23.1 CNV rs1772408 Disease risk Negative
IFI16 Homo sapiens 1q23.1 CNV rs62621173 Disease risk Negative
IFI16 Homo sapiens 1q23.1 CNV rs1772408 Disease risk Negative
IFI16 Homo sapiens 1q23.1 CNV rs62621173 Disease risk Negative
TNF Homo sapiens 6p21.33 polymorphism TNF1/l ,TNF1 /2 ,TNF2/2 Disease risk Negative
SYN3 Homo sapiens 22q12.3 SNP g–196 (G > A) Disease risk Negative
SYN3 Homo sapiens 22q12.3 SNP g–631 (C > G) Disease risk Positive
SYN3 Homo sapiens 22q12.3 haplotype C631 haplotype Disease risk Positive
SYN3 Homo sapiens 22q12.3 haplotype A196 haplotype Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DRB1*0901 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DRB1*1501 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 allele DPB1*0501 Disease risk Negative
CCR5 Homo sapiens 3p21.31 polymorphism, allele N/A Disease risk Negative
Val158Met Homo sapiens 22q11.21 polymorphism rs4680 Val158Met (Val/Val, Val/Met,and Met/Met) Disease risk Negative
Val158Met Homo sapiens 22q11.21 polymorphism rs4680 Val158Met (Val/Val, Val/Met,and Met/Met) Phenotypic risk Positive
IL1A Homo sapiens 2q14.1 polymorphism -889 C/T Disease risk Negative
IL1B Homo sapiens 2q14.1 polymorphism -511 C/T Disease risk Negative
FOXP3 Homo sapiens Xp11.23 SNP rs3761548 Disease risk Positive
FOXP3 Homo sapiens Xp11.23 SNP rs2232365 Disease risk Positive
CNTF Homo sapiens 11q12.1 SNP the G-to-A CNTF null mutation at position -6 of the second exon(CNTF -/-) Disease risk Negative
IL2 Homo sapiens 4q27 allele IL2 -330 GT , TT ,GG Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DRBl*I501,DRBS*0I01,DQAl*OlO2,DQB1*0602 Disease risk Positive
NOS1 Homo sapiens 12q24.22 allele N/A Disease risk Negative
NINJ2 Homo sapiens 12p13.33 SNP rs11833579 Disease risk Negative
NINJ2 Homo sapiens 12p13.33 SNP rs3809263 Disease risk Positive
PECAM1 Homo sapiens 17q23.3 allele Amplicon length (bp):P1 (119),P2 (121),P3 (123),P4 (125),P5 (127),P6 (129),P7 (131) Disease risk Negative
MPO Homo sapiens 17q22 allele N/A Disease risk Negative
MPO Homo sapiens 17q22 SNP G/G, G/A and A/A Disease risk Negative
PRKAR1A Homo sapiens 17q24.2 allele N/A Disease risk Negative
SYN3 Homo sapiens 22q12.3 SNP rs133946 Disease risk Negative
SYN3 Homo sapiens 22q12.3 SNP rs133945 Disease risk Negative
APOC2 Homo sapiens 19q13.32 allele (TG)n(AG)m allele Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP 1595C/T Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 allele HLA-DQB1*0602 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*15 +/- Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele residue 86 polymorphism Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 allele N/A Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Phenotypic risk Positive
HLA-DQB1 Homo sapiens 6p21.32 allele N/A Phenotypic risk Positive
MBP Homo sapiens 18q23 polymorphism N/A Disease risk ,Phenotypic risk Positive
IL1RN Homo sapiens 2q14.1 allele A2+,A2- Disease risk Positive
PNMT Homo sapiens 17q12 polymorphism G (-387)/A (-387) and G (-182)/A (-182) Disease risk Positive
NOTCH4 Homo sapiens 6p21.32 SNP rs422951 Disease risk Positive
HLA-DQA2 Homo sapiens 6p21.32 SNP rs3997849 Disease risk Positive
CFB Homo sapiens 6p21.33 allele N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
STAT3 Homo sapiens 17q21.2 SNP rs3809758/rs744166/rs1026916/rs12948909 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Negative
CCL2 Homo sapiens 17q12 SNP -2138A>T Disease risk Positive
CCL11 Homo sapiens 17q12 SNP -488C>A Disease risk Positive
IL6 Homo sapiens 7p15.3 polymorphism C allele present or absent Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk Positive
TNF Homo sapiens 6p21.33 allele N/A Disease risk Negative
SERPINA1 Homo sapiens 14q32.13 allele M3 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DRB1*1501 Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele DRB1*1501-positive and -negative Disease risk Negative
HLA-B Homo sapiens 6p21.33 allele HLA B*44 Disease risk Positive
TRBV20OR9-2 Homo sapiens 9p13.3 polymorphism N/A Disease risk Negative
CD40 Homo sapiens 20q13.12 polymorphism C/T Disease risk Negative
CLEC16A Homo sapiens 16p13.13 SNP rs725613 Disease risk Positive
IFNL3 Homo sapiens 19q13.2 SNP rs8099917 Treatment risk Negative
IFNL3 Homo sapiens 19q13.2 SNP rs12979860 Treatment risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*04:05 or *15:01 Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele-haplotype N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele-haplotype N/A Phenotypic risk Positive
HLA-DRB2 Homo sapiens 6p21.3 allele-haplotype N/A Disease risk Positive
HLA-DRB3 Homo sapiens 6p21.3 allele-haplotype N/A Phenotypic risk Positive
HLA-DRB4 Homo sapiens 6p21.3 allele-haplotype N/A Phenotypic risk Positive
HLA-DRB6 Homo sapiens 6p21.32 allele-haplotype N/A Disease risk Positive
IL2RA Homo sapiens 10p15.1 methylation N/A Disease risk Positive
IFNAR1 Homo sapiens 21q22.11 SNP rs2850015 Treatment risk Positive
A2M Homo sapiens 12p13.31 Deletion Exon 18Del Disease risk Negative
A2M Homo sapiens 12p13.31 polymorphism Val 1000 Iso Disease risk Negative
LRP6 Homo sapiens 12p13.2 polymorphism A216V Disease risk Negative
CNR1 Homo sapiens 6q15 allele short AAT , long AAT Phenotypic risk Negative
HLA-A Homo sapiens 6p22.1 allele N/A Disease risk ; Phenotypic risk Negative
HLA-B Homo sapiens 6p21.33 allele N/A Disease risk ; Phenotypic risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Phenotypic risk Negative
HLA-DRB1 Homo sapiens 6p21.32 DNA methylation at CpG dinucleotides N/A Phenotypic risk Negative
HLA-DRB5 Homo sapiens 6p21.32 DNA methylation at CpG dinucleotides N/A Phenotypic risk Negative
NCF1 Homo sapiens 7q11.23 Deletion dinucleotide deletion (ΔGT) in exon 2 Disease risk Negative
NCF1 Homo sapiens 7q11.23 Deletion dinucleotide deletion (ΔGT) in exon 2 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs2055979 Disease risk Positive
MMP9 Homo sapiens 20q13.12 polymorphism 1562 C/T Disease risk Positive
MMP9 Homo sapiens 20q13.12 polymorphism 1562 C/T Phenotypic risk Negative
LEP Homo sapiens 7q32.1 SNP rs2167270 or 19G > A Disease risk Positive
LEP Homo sapiens 7q32.1 SNP rs7799039 or -2,548G > A Disease risk Positive
LEP Homo sapiens 7q32.1 SNP rs2167270 or 19G > A Phenotypic risk Negative
LEP Homo sapiens 7q32.1 SNP rs7799039 or -2,548G > A Phenotypic risk Negative
ADIPOQ Homo sapiens 3q27.3 SNP rs1501299 or +276G > T Disease risk Positive
ADIPOQ Homo sapiens 3q27.3 SNP rs266729 or -11,377C > G Disease risk Positive
ADIPOQ Homo sapiens 3q27.3 SNP rs1501299 or +276G > T Phenotypic risk Positive
IL1B Homo sapiens 2q14.1 polymorphism N/A Disease risk Negative
IL1RN Homo sapiens 2q14.1 polymorphism N/A Disease risk Negative
IL6 Homo sapiens 7p15.3 SNP rs1818879 Phenotypic risk Positive
IFNG Homo sapiens 12q15 SNP 874A/T Disease risk Positive
TNF Homo sapiens 6p21.33 SNP 308A/G Disease risk Positive
KIF5A Homo sapiens 12q13.3 SNP rs703842 Phenotypic risk Positive
KIF5A Homo sapiens 12q13.3 SNP rs12368653 Phenotypic risk Positive
APOE Homo sapiens 19q13.32 allele epsilon4 Allele positive / negative Disease risk Negative
NR3C1 Homo sapiens 5q31.3 SNP N/A Treatment risk Negative
TNF Homo sapiens 6p21.33 allele –308 in the TNFα promotor Disease risk Negative
CFH Homo sapiens 1q31.3 allele-haplotype Tyr402 Disease risk Negative
IFNLR1 Homo sapiens 1p36.11 SNP rs4649203 Disease risk Negative
MIF Homo sapiens 22q11.23 SNP 173 G/C Phenotypic risk Positive
DDT Homo sapiens 22q11.23 polymorphism rs5844572(794 CATT5–8) Phenotypic risk Positive
CD58 Homo sapiens 1p13.1 SNP rs12044852 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs6498169 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
CBLB Homo sapiens 3q13.11 SNP rs12487066 Disease risk Positive
CNTF Homo sapiens 11q12.1 mutation N/A Phenotypic risk Negative
TNF Homo sapiens 6p21.33 polymorphism TNFα–308 Phenotypic risk Negative
HLA-G Homo sapiens 6p22.1 Insertion 14bp Phenotypic risk Positive
HLA-G Homo sapiens 6p22.1 Deletion 14bp Phenotypic risk Positive
HLA-G Homo sapiens 6p22.1 polymorphism +3142C>G Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
CXCL12 Homo sapiens 10q11.21 polymorphism SDF-13'a Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs7206912,rs6498168,rs9934231,rs6498169,rs8060411 Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs12708716 , rs12923849 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
LEP Homo sapiens 7q32.1 SNP rs11761556,rs2167270,rs7799039 Disease risk Negative
LEPR Homo sapiens 1p31.3 SNP rs1137100,rs1137101,rs8179183 Disease risk Negative
GHRL Homo sapiens 3p25.3 SNP rs696217,rs1629816,rs4684677 Disease risk Negative
GHSR Homo sapiens 3q26.31 SNP rs519384,rs509035,rs5772169 Disease risk Negative
SPP1 Homo sapiens 4q22.1 SNP rs1126616 Disease risk Negative
IRF1 Homo sapiens 5q31.1 allele GT repeat alleles Disease risk Negative
NRG1 Homo sapiens 8p12 SNP rs6994992 Disease risk Negative
NRG1 Homo sapiens 8p12 SNP rs7014762 Disease risk Negative
NRG1 Homo sapiens 8p12 SNP rs6994992 Phenotypic risk Positive
NRG1 Homo sapiens 8p12 SNP rs7014762 Phenotypic risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs725613, rs2041670, rs2080272, rs998592 Disease risk Positive
HNMT Homo sapiens 2q22.1 polymorphism Thr/Ile Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs7975232 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk Negative
MMP9 Homo sapiens 20q13.12 polymorphism N/A Disease risk Negative
APOE Homo sapiens 19q13.32 allele N/A Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Treatment risk Negative
PTPN6 Homo sapiens 12p13.31 methylation N/A Disease risk Positive
MTHFR Homo sapiens 1p36.22 polymorphism C677T Disease risk Positive
SLFN12 Homo sapiens 17q12 methylation N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 methylation-mediated SNP rs9267649 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP CT60 Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP 49A/G Disease risk Negative
HLA-G Homo sapiens 6p22.1 SNP rs1611715 Disease risk Positive
APOE Homo sapiens 19q13.32 polymorphism N/A Treatment risk Negative
CCL20 Homo sapiens 2q36.3 SNP rs6749704 Disease risk Positive
IL17F Homo sapiens 6p12.2 SNP rs763780 Disease risk Positive
TNF Homo sapiens 6p21.33 polymorphism 376a Disease risk Negative
ARSA Homo sapiens 22q13.33 polymorphism ASA-PD (N350S and 1524+95A-G) Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Phenotypic risk Negative
HLA-A Homo sapiens 6p22.1 allele N/A Phenotypic risk Negative
IL6 Homo sapiens 7p15.3 SNP rs1800796 Disease risk Positive
TAGAP Homo sapiens 6q25.3 SNP rs1738074,rs3127214 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 haplotype N/A Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722489,rs2104286 Disease risk Negative
TNF Homo sapiens 6p21.33 SNP —308 polymorphism Phenotypic risk Negative
NECTIN2 Homo sapiens 19q13.32 SNP rs394221 Disease risk Positive
HLA-A Homo sapiens 6p22.1 haplotype N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 haplotype N/A Disease risk Positive
IL6 Homo sapiens 7p15.3 polymorphisms N/A Phenotypic risk Negative
IGHM Homo sapiens 14q32.33 haplotypes N/A Disease risk Negative
CYP24A1 Homo sapiens 20q13.2 SNP rs2762943 Disease risk up-regulation
SIRT1 Homo sapiens 10q21.3 SNP rs3758391 Disease risk N/A
SIRT1 Homo sapiens 10q21.3 SNP rs7895833 Disease risk N/A
IL4 Homo sapiens 5q31.1 gene are in strong linkage disequilibrium rs2070874 Disease risk protective
MPO Homo sapiens 17q22 myeloperoxidase promoter polymorphism position 1856–2629 of MPO N/A N/A
IL10 Homo sapiens 1q32.1 diallelic polymorphism position –1082 in the IL10 promotor N/A Negative
CTLA4 Homo sapiens 2q33.2 Polymorphism of the CTLA-4 gene dinucleotide microsatelite (AT) N/A Negative
HLA-DRB1 Homo sapiens 6p21.32 multiallelic polymorphisms DRB1*1501 Disease risk MS susceptibility is conferred by HLA class II alleles
HLA-DQA1 Homo sapiens 6p21.32 multiallelic polymorphisms DQA1*0102 Disease risk MS susceptibility is conferred by HLA class II alleles
HLA-DQB1 Homo sapiens 6p21.32 multiallelic polymorphisms DQB1*0602 Disease risk MS susceptibility is conferred by HLA class II alleles
TNF Homo sapiens 6p21.33 gene polymorphism N/A Disease risk Negative
NOTCH4 Homo sapiens 6p21.32 SNP rs422951 Disease risk negative
KCNA3 Homo sapiens 1p13.3 SNP rs2821557 Disease risk positive
NR3C1 Homo sapiens 5q31.3 SNP rs6189/6190 Disease risk positive
NR3C1 Homo sapiens 5q31.3 SNP rs56149945 Disease risk positive
NR3C1 Homo sapiens 5q31.3 SNP rs41423247 Disease risk positive
GAS5 Homo sapiens 1q25.1 SNP rs55829688 Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*15:01 Disease risk not related
GAPVD1 Homo sapiens 9q33.3 SNP rs2291858 Disease risk negative
LINGO1 Homo sapiens 15q24.3 SNP rs11856808 Disease risk not related
LINGO1 Homo sapiens 15q24.3 SNP rs9652490 Disease risk not related
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*15:01 Disease risk positive
IL4 Homo sapiens 5q31.1 SNP VNTR and +33 C/T Disease risk positive
IL4 Homo sapiens 5q31.1 SNP Q551*R Disease risk positive
PDCD1 Homo sapiens 2q37.3 intronic polymorphism 7146G/A Disease risk positive
IL13 Homo sapiens 5q31.1 promoter polymorphism IL-131024TT Disease risk no association
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*15:01 Disease risk positive
IL23R Homo sapiens 1p31.3 SNP rs10127763 rs6656929 rs10489630 rs1004819 rs790633 rs7517847 rs10489629 rs7528924 rs12070470 rs12030948 rs11465804 rs4655530 rs10789229 rs11209026 rs1343151 rs6693831 rs10889677 rs2863209 rs11209030 rs11209032 rs6660226 rs1495965 rs7539817 rs10889680 rs12 Disease risk N/A
TYK2 Homo sapiens 19p13.2 SNP rs34536443 Disease risk negative
NLRP3 Homo sapiens 1q44 SNP rs35829419 Disease risk negative
IL22 Homo sapiens 12q15 gene polymorphism N/A Disease risk positive
SLC11A1 Homo sapiens 2q35 SNP rs2276631 Disease risk positive
SLC11A1 Homo sapiens 2q35 SNP rs3731865 Disease risk N/A
SLC11A1 Homo sapiens 2q35 SNP rs3731864 Disease risk N/A
SLC11A1 Homo sapiens 2q35 SNP rs17221959 Disease risk N/A
SLC11A1 Homo sapiens 2q35 SNP rs2695342 Disease risk N/A
SLC11A1 Homo sapiens 2q35 SNP rs2279015 Disease risk N/A
SLC11A1 Homo sapiens 2q35 SNP rs17235409 Disease risk N/A
SLC11A1 Homo sapiens 2q35 SNP rs17235416 Disease risk N/A
MOG Homo sapiens 6p22.1 aminoacid substitution a G→A transition occurring in exon 3 of the human MOG gene. Disease risk no association
VDR Homo sapiens 12q13.11 SNP rs1544410(BsmI)、rs7975232(ApaI)、rs731236(TaqI)、rs10735810(FokI)、rs11568820(Cdx-2) Disease risk N/A
CYP27B1 Homo sapiens 12q14.1 SNP rs703426、rs10877012 Disease risk N/A
CYP24A1 Homo sapiens 20q13.2 SNP rs2296241 Disease risk N/A
CYP2R1 Homo sapiens 11p15.2 SNP rs10500804, rs12794714 Disease risk N/A
DBP Homo sapiens 19q13.33 SNP rs7041、rs4588 Disease risk N/A
CD6 Homo sapiens 11q12.2 SNP rs12288280 Disease risk positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs767455 Disease risk positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs1800693 Disease risk positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149577 Disease risk positive
IRF8 Homo sapiens 16q24.1 SNP rs767455 Disease risk N/A
STAT4 Homo sapiens 2q32.2-q32.3 SNP rs7574865 Disease risk positive
MIR146A Homo sapiens 5q33.3 SNP rs2910164 Disease risk positive
KIF5A Homo sapiens 12q13.3 SNP rs1678542 Disease risk positive
SH2B3 Homo sapiens 12q24.12 SNP rs3184504 Disease risk positive
CD226 Homo sapiens 18q22.2 SNP rs763361 Disease risk positive
IFNAR1 Homo sapiens 21q22.11 SNP rs# 2243590,rs# 2252931,rs# 2243600 Disease risk N/A
IFNAR2 Homo sapiens 21q22.11 SNP rs# 2300370,rs# 2248412,rs# 2834154,rs# 2154430,rs# 2236756,rs# 2284549,rs# 2284551,rs# 2834163,rs #2236757,rs #2236758 Disease risk N/A
STAT1 Homo sapiens 2q32.2 SNP rs# 2066802,rs# 1547550 Disease risk positive
STAT2 Homo sapiens 12q13.3 SNP rs# 2066818,rs# 2066819,rs# 2020854,rs# 2066811 Disease risk N/A
IRF1 Homo sapiens 5q31.1 SNP rs# 2070721 Disease risk positive
VDR Homo sapiens 12q13.11 SNP ApaI(rs7975232) Disease risk negative
VDR Homo sapiens 12q13.11 SNP BsmI(rs1544410) Disease risk positive
VDR Homo sapiens 12q13.11 SNP TaqI(rs731236) Disease risk negative
VDR Homo sapiens 12q13.11 SNP FokI(rs222870) Disease risk positive
ZC3HAV1 Homo sapiens 7q34 SNP rs3735007 Disease risk positive
IL2 Homo sapiens 4q27 allele IL-2 330 T/HLA-DRB1*1501 Disease risk positive
HOTAIR Homo sapiens 12q13.13 SNP rs920778 Disease risk Positive
CDKN2B-AS1 Homo sapiens 9p21.3 SNP rs10757278 Disease risk Positive
CDKN2B-AS1 Homo sapiens 9p21.3 SNP rs1333045 Disease risk Positive
LAMP2 Homo sapiens Xq24 SNP rs1194422515; rs42895; rs41300191; rs42886 Disease risk Positive
AVPR2 Homo sapiens Xq28 SNP Affx-89,012,620; Affx89,008,152; Affx89,010,658 Disease risk Positive
MTMR8 Homo sapiens Xq11.2 SNP rs766668643 Disease risk Positive
F8 Homo sapiens Xq28 SNP rs369414658 Disease risk Positive
PORCN Homo sapiens Xp11.23 SNP rs1556974235 Disease risk Positive
ELF4 Homo sapiens Xq26.1 SNP rs373568641 Disease risk Positive
NSDHL Homo sapiens Xq28 SNP rs797045835 Disease risk Positive
HS6ST2 Homo sapiens Xq26.2 SNP rs950792996 Disease risk Positive
RBM10 Homo sapiens Xp11.3 SNP rs139585263 Disease risk Positive
AR Homo sapiens Xq12 SNP rs367604031 Disease risk Positive
TAFAZZIN Homo sapiens Xq28 SNP rs387907218; Affx89,017,095 Disease risk Positive
RIBC1 Homo sapiens Xp11.22 SNP rs782346908 Disease risk Positive
BCOR Homo sapiens Xp11.4 SNP rs199676230 Disease risk Positive
DKC1 Homo sapiens Xq28 SNP rs121912302 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Gene polymorphisms G511525 and D6S1666 Disease risk Positive
ACE Homo sapiens 17q23.3 Gene polymorphisms ACE I/D Disease risk Negative
ACE Homo sapiens 17q23.3 Gene polymorphisms ATG M235T Disease risk Negative
ACE Homo sapiens 17q23.3 Gene polymorphisms ATG (6)A/G Disease risk Negative
APOE Homo sapiens 19q13.32 SNP rs7412 (C/T) Disease risk Positive
APOE Homo sapiens 19q13.32 SNP rs429358 (C/T) Disease risk Positive
FUT1 Homo sapiens 19q13.33 alleles N/A Disease risk Positive
FUT2 Homo sapiens 19q13.33 alleles N/A Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs1570538 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs10795791 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs4147359 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs7090530 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs41295061 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs35285258 Disease risk Positive
TNF Homo sapiens 6p21.33 promoter polymorphism TNF-376A Disease risk Positive
MOG Homo sapiens 6p22.1 Gene polymorphisms N/A Disease risk Positive
KIR3DL1 Homo sapiens 19q13.42 SNP N/A Disease risk Positive
HLA-B Homo sapiens 6p21.33 SNP HLA-Bw4 Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs1883832CT Disease risk Negative
CD40 Homo sapiens 20q13.12 SNP rs1883832CC Disease risk Negative
CD40 Homo sapiens 20q13.12 SNP rs1883832TT Disease risk Negative
ASAP2 Homo sapiens 2p25.1; 2p24 SNP rs1109670 Disease risk Negative
PDZRN4 Homo sapiens 12q12 SNP rs1458175 Disease risk Negative
CSMD1 Homo sapiens 8p23.2 SNP rs1529316 Disease risk Negative
CSMD1 Homo sapiens 8p23.2 SNP rs2049306 Disease risk Negative
TBC1D2 Homo sapiens 9q22.33 SNP rs16914086 Disease risk Negative
SH3GL2 Homo sapiens 9p22.2 SNP rs1755289 Disease risk Negative
ZIC1 Homo sapiens 3q24 SNP rs1841770 Disease risk Negative
EN1 Homo sapiens 2q14.2 SNP rs651477 Disease risk Negative
TRIB2 Homo sapiens 2p24.3 SNP rs7607490 Disease risk Negative
TMEM74B Homo sapiens 20p13 SNP rs397020 Disease risk Negative
SLC25A36 Homo sapiens 3q23 SNP rs908821 Disease risk Negative
TENM3-AS1 Homo sapiens 4q34.3 SNP rs7672826 Disease risk Negative
GPC5 Homo sapiens 13q31.3 SNP rs9523762 Disease risk Positive
SH2D2A Homo sapiens 1q23.1 SNP rs2768766 Disease risk Positive
SH2D2A Homo sapiens 1q23.1 SNP rs909200 Disease risk Positive
SH2D2A Homo sapiens 1q23.1 SNP rs926103 Disease risk Positive
SH2D2A Homo sapiens 1q23.1 SNP rs1800600 Disease risk Positive
SH2D2A Homo sapiens 1q23.1 SNP GA repeat polymorphism Disease risk Positive
SH2D2A Homo sapiens 1q23.1 SNP rs2768764 Disease risk Positive
IL23R Homo sapiens 1p31.3 SNP rs7517847 Disease risk Negative
IL23R Homo sapiens 1p31.3 SNP rs11209026 Disease risk Positive
IL12B Homo sapiens 5q33.3 SNP rs6887695 Disease risk Negative
IL12B Homo sapiens 5q33.3 SNP rs3212227 Disease risk Negative
MMP9 Homo sapiens 20q13.12 promoter polymorphism MMP-9 PM ≥22 CA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*15 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 allele HLA-DRB1*04 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV2S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV3S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV6S5 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV8S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV8S2 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV8S3 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV10S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV12S2 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV15S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV16S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV21S4 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV24S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV25S1 Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Gene Polymorphism BV26S1 Disease risk Negative
NPY Homo sapiens 7p15.3 SNP rs16139 Disease risk Positive
NPY Homo sapiens 7p15.3 SNP rs16147 Disease risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs1800693 Disease risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149584 Disease risk Positive
IL1B Homo sapiens 2q14.1 SNP -500 C/T ï¼›rs16944 Disease risk Positive
IL1B Homo sapiens 2q14.1 SNP +3954 C/T ;rs1143634 Disease risk Positive
IL1A Homo sapiens 2q14.1 SNP -889 C/T; rs1800587 Disease risk Positive
IL1A Homo sapiens 2q14.1 SNP +4845 G/T; rs17561 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs11567685 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs1494555 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs987106 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs3194051 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs11256369 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs7076103 Disease risk Positive
IFNG Homo sapiens 12q15 gene Polymorphism N/A Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 gene Polymorphism N/A Disease risk Positive
IL21 Homo sapiens 4q27 SNP rs13151961 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs6822844 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs925549 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs17879298 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs907715 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs4833837 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs13143866 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs17005929 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs17005931 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs12505138 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs4326027 Disease risk Negative
IL21 Homo sapiens 4q27 SNP rs6840978 Disease risk Negative
CRYAB Homo sapiens 11q23.1 gene Polymorphism -C249G Disease risk Negative
CRYAB Homo sapiens 11q23.1 gene Polymorphism -C650G Disease risk Positive
CRYAB Homo sapiens 11q23.1 gene Polymorphism -A652G Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 alleles N/A Disease risk Positive
TNF Homo sapiens 6p21.33 alleles N/A Disease risk Positive
TGFB1 Homo sapiens 19q13.2 alleles N/A Disease risk Positive
CTLA4 Homo sapiens 2q33.2 alleles N/A Disease risk Positive
CCR5 Homo sapiens 3p21.31 alleles N/A Disease risk Positive
PLAT Homo sapiens 8p11.21 insertion/deletion (I/D) genetic polymorphism TPA DD/PAI-1 4G4G Disease risk Positive
SERPINE1 Homo sapiens 7q22.1 insertion/deletion (I/D) genetic polymorphism TPA DD/PAI-1 4G4G Disease risk Positive
IFNG Homo sapiens 12q15 allele I1(761)*CA12 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 haplotypic diversity HLA-DRB1*1501 Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 haplotypic diversity HLA-DQB1*0602 Disease risk Positive
PRF1 Homo sapiens 10q22.1 mutations N/A Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP 1577 GG Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP +6230 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP +10242 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP +10717 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP +12310 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP -658 Disease risk Positive
APOE Homo sapiens 19q13.32 gene polymorphism -491 A/T Disease risk Positive
CTLA4 Homo sapiens 2q33.2 exon 1 dimorphism ( + 49)A/G Phenotypic risk Positive
HSPA4 Homo sapiens 5q31.1 gene polymorphism hsp70 -2 (+1267 A/G) Disease risk Positive
VDR Homo sapiens 12q13.11 intragenic restriction fragment length polymorphisms N/A Disease risk Positive
ENPEP Homo sapiens 4q25 intragenic restriction fragment length polymorphisms N/A Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs987107 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP T244 Disease risk Positive
IL4 Homo sapiens 5q31.1 gene polymorphisms C/C, T/C, and T/T genotypes of the -590 region of IL-4 Disease risk Positive
ACE Homo sapiens 17q23.3 insertion/deletion gene polymorphism N/A Disease risk Positive
HLA-DPB1 Homo sapiens 6p21.32 allele DRB1*1501 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 allele DPB1*0301 Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 allele DPB1*0501 Disease risk Negative
IFNG Homo sapiens 12q15 allelic located in the first intron of the interferon-gamma gene Phenotypic risk Positive
HSPA1B Homo sapiens 6p21.33 SNP rs1061581 Disease risk Positive
GRIN2A Homo sapiens 16p13.2 SNP rs3859123 Phenotypic risk Positive
GRIN2A Homo sapiens 16p13.2 SNP rs9927924 Phenotypic risk Positive
GRIN2A Homo sapiens 16p13.2 SNP rs6497658 Phenotypic risk Positive
GRIN2A Homo sapiens 16p13.2 SNP rs13338243 Phenotypic risk Positive
GRIN2A Homo sapiens 16p13.2 SNP rs1070484 Phenotypic risk Positive
GRIN2A Homo sapiens 16p13.2 SNP rs3104703 Phenotypic risk Positive
MEFV Homo sapiens 16p13.3 gene variants N/A Treatment risk Negative
IL10 Homo sapiens 1q32.1 SNP rs3135932 Disease risk Positive
HLA-G Homo sapiens 6p22.1 insertion/ deletion N/A Disease risk Positive
IFNG Homo sapiens 12q15 SNP rs2069727 Disease risk Positive
TNF Homo sapiens 6p21.33 gene polymorphisms 一308G／A Disease risk Positive
VDR Homo sapiens 12q13.11 gene polymorphisms N/A Disease risk Positive
ZFAT Homo sapiens 8q24.22 SNP rs733254 Disease risk Positive
ZFAT Homo sapiens 8q24.22 SNP rs12557782 Disease risk Positive
ZFAT Homo sapiens 8q24.22 SNP rs2229857 Disease risk Positive
ZFAT Homo sapiens 8q24.22 SNP rs9527281 Disease risk Positive
ZFAT Homo sapiens 8q24.22 SNP rs11787532 Disease risk Positive
ZFAT Homo sapiens 8q24.22 SNP rs7308076 Disease risk Positive
ZFAT Homo sapiens 8q24.22 SNP rs2248202 Disease risk Positive
TNF Homo sapiens 6p21.33 gene polymorphisms A (/ 238 allele Disease risk Positive
TNF Homo sapiens 6p21.33 gene polymorphisms GGhaplotypes Disease risk Positive
TNF Homo sapiens 6p21.33 gene polymorphisms GAhaplotypes Disease risk Positive
IL2 Homo sapiens 4q27 gene polymorphisms GG (/ 330 genotype Disease risk Positive
IL6 Homo sapiens 7p15.3 gene polymorphisms C (/ 174 allele Disease risk Positive
IL6 Homo sapiens 7p15.3 gene polymorphisms CGhaplotypes Disease risk Positive
IL6 Homo sapiens 7p15.3 gene polymorphisms GGhaplotypes Disease risk Positive
IL6 Homo sapiens 7p15.3 gene polymorphisms GGgenotypes Disease risk Positive
IL6 Homo sapiens 7p15.3 gene polymorphisms CGgenotypes Disease risk Positive
CCL20 Homo sapiens 2q36.3 SNP rs6749704 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs2228570 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs1544410 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs6763816 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs11545817 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs1047275 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs16845759 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs7011559 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs4491934 Disease risk Positive
TNFSF10 Homo sapiens 3q26.31 SNP rs1131579 Disease risk Positive
TLR3 Homo sapiens 4q35.1 SNP rs116729895 Disease risk N/A
TLR3 Homo sapiens 4q35.1 SNP rs3775296 Disease risk N/A
TLR3 Homo sapiens 4q35.1 SNP rs377529 Disease risk N/A
TLR3 Homo sapiens 4q35.1 SNP rs3775290 Disease risk N/A
TLR3 Homo sapiens 4q35.1 SNP rs3775291 Disease risk Positive
TLR3 Homo sapiens 4q35.1 SNP rs376735334 Disease risk N/A
TLR3 Homo sapiens 4q35.1 SNP rs73873710 Disease risk N/A
SOCS1 Homo sapiens 16p13.13 SNP rs243324 Disease risk Positive
ANKRD55 Homo sapiens 5q11.2 SNP rs6859219 Disease risk Positive
IL22RA2 Homo sapiens 6q23.3 SNP rs276474 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
HMOX2 Homo sapiens 16p13.3 SNP rs1051308AA Disease risk Positive
HMOX2 Homo sapiens 16p13.3 SNP rs1051308A Disease risk Positive
HMOX1 Homo sapiens 22q12.3 SNP rs2071746A Disease risk Positive
VAV1 Homo sapiens 19p13.3 SNP rs2546133-rs2617822 Disease risk Positive
CCL22 Homo sapiens 16q21 SNP rs223889 Disease risk Positive
CCL22 Homo sapiens 16q21 SNP rs4359426 Disease risk Positive
CCL17 Homo sapiens 16q21 SNP rs223828 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-DQB1*06:02、rs9273342 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-A*2:01、rs28844821 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-DPB1*03:01、DPB1-2939-33046757-intron1 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-DRB1*13:03:01、rs75589097 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-DQB1*02:01、DQB1-6203-32628182-intron 5 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-DRB1*15:01、rs9269243 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP r6929950 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-DRB1*15:01、rs9269243 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-A*02:01、rs12153924 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP HLA-B*53:01、rs115219755 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP rs760145 Disease risk Positive
FCRL3 Homo sapiens 1q23.1 A functional promoter polymorphism -169 T/C Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs7093069 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs12722598 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP rs3087243 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP rs231775 Disease risk Negative
CTLA4 Homo sapiens 2q33.2 SNP rs5742906 Disease risk Negative
CD40 Homo sapiens 20q13.12 SNP rs1883832 Disease risk Negative
PADI4 Homo sapiens 1p36.13 SNP rs1748033 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*1501 Disease risk Positive
HLA-DRB5 Homo sapiens 6p21.32 SNP DRB5*0101 Disease risk Positive
APOE Homo sapiens 19q13.32 Gene polymorphisms 112C/R Disease risk Positive
APOE Homo sapiens 19q13.32 Gene polymorphisms 158R/C Disease risk Positive
IL1B Homo sapiens 2q14.1 Gene polymorphisms –511T/C Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388 Disease risk Positive
EVI5 Homo sapiens 1p22.1 SNP rs10735781 Disease risk Positive
EVI5 Homo sapiens 1p22.1 SNP rs6680578 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs689732 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk Negative
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Negative
EVI5 Homo sapiens 1p22.1 SNP rs10735781 Disease risk Positive
EVI5 Homo sapiens 1p22.1 SNP rs6680578 Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs1335532 Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs2300747 Disease risk Negative
APOE Homo sapiens 19q13.32 Alleles ε4、ε3/ε4 Disease risk Positive
APOE Homo sapiens 19q13.32 Alleles ε2/ε3 Disease risk Negative
APOE Homo sapiens 19q13.32 Alleles ε3/ε3 Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF-alpha - 238 G-->A Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF-alpha - 308 G-->A Disease risk Negative
IL10 Homo sapiens 1q32.1 Gene polymorphisms L-10 - 1082 Disease risk Positive
TAP1 Homo sapiens 6p21.32 Gene polymorphisms TAP1 - 1069 Disease risk Negative
TAP1 Homo sapiens 6p21.32 Gene polymorphisms TAP1 - 1982 Disease risk Negative
TAP2 Homo sapiens 6p21.32 Gene polymorphisms TAP2 - 1231 Disease risk Negative
TAP2 Homo sapiens 6p21.32 Gene polymorphisms TAP2 - 2089 Disease risk Negative
TAP2 Homo sapiens 6p21.32 Gene polymorphisms TAP2 - 2155 Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF - 376 Disease risk Positive
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF - 238 Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF - 308 Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF - 238 Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF - 308 Disease risk Negative
TNF Homo sapiens 6p21.33 Alleles a11 Disease risk Positive
MBP Homo sapiens 18q23 Gene polymorphisms a tetranucleotide (TGGA)n repeat polymorphism 5' Disease risk Negative
APOE Homo sapiens 19q13.32 Gene polymorphisms E4 - ε2 Disease risk Positive
APOE Homo sapiens 19q13.32 Gene polymorphisms E4 - ε3 Disease risk Negative
APOE Homo sapiens 19q13.32 Gene polymorphisms E4 - ε4 Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*14 - Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*11 - Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*01 - Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*10 - Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*15 - Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*17 - Disease risk Positive
CIITA Homo sapiens 16p13.13 SNP rs4774 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*15:01 Disease risk Positive
MMP9 Homo sapiens 20q13.12 SNP rs3918242 Disease risk Positive
PRRC2A Homo sapiens 6p21.33 SNP rs2242659 Disease risk Positive
PRRC2A Homo sapiens 6p21.33 SNP rs2844470 Disease risk Positive
PRRC2A Homo sapiens 6p21.33 SNP rs2736157 Disease risk Positive
PRRC2A Homo sapiens 6p21.33 SNP rs2736171 Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs2300747 Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs12044852 Disease risk Positive
CD6 Homo sapiens 11q12.2 SNP rs929230 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs1544410 Disease risk Positive
AGER Homo sapiens 6p21.32 Gene polymorphisms p.82G>S Disease risk Positive
NOS2 Homo sapiens 17q11.2 SNP rs2301369 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs8078340 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs9282799 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs2779248 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs3730013 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs3794764 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs3729508 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs1137933 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs4796052 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs2248814 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs2297518 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs1060826 Disease risk Negative
NOS2 Homo sapiens 17q11.2 SNP rs8081248 Disease risk Negative
VEGFA Homo sapiens 6p21.1 SNP rs3025039 Disease risk Positive
KDR Homo sapiens 4q12 SNP rs2071559 Disease risk Negative
IL17F Homo sapiens 6p12.2 SNP rs763780 Disease risk Positive
IL17A Homo sapiens 6p12.2 SNP rs2275913 Disease risk Negative
MTHFR Homo sapiens 1p36.22 SNP rs1801133 Disease risk Negative
MTHFR Homo sapiens 1p36.22 SNP rs1801131 Disease risk Negative
VDR Homo sapiens 12q13.11 Gene polymorphisms ApaI Disease risk Negative
VDR Homo sapiens 12q13.11 Gene polymorphisms BsmI Disease risk Negative
VDR Homo sapiens 12q13.11 Gene polymorphisms TaqI Disease risk Negative
VDR Homo sapiens 12q13.11 Gene polymorphisms BsmI BB（AA） Disease risk Positive
FAS Homo sapiens 10q23.31 SNP rs2234978 Disease risk Positive
KCNIP1 Homo sapiens 5q35.1 SNP rs11957313 Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs8056098 Disease risk Positive
MOG Homo sapiens 6p22.1 SNP rs3130253 Disease risk Positive
NCAN Homo sapiens 19p13.11 SNP rs1064395 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP rs5742909 Disease risk Positive
FAS Homo sapiens 10q23.31 SNP rs2234978 Disease risk Positive
PLXNA3 Homo sapiens Xq28 SNP rs5945430 Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs2300747 A>G Disease risk Negative
CD226 Homo sapiens 18q22.2 SNP rs763361 C>T Disease risk Positive
HLA-G Homo sapiens 6p22.1 SNP rs1611715 A>C Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP rs2647040 Disease risk Positive
HLA-C Homo sapiens 6p21.33 SNP rs3135021 Disease risk Positive
TYK2 Homo sapiens 19p13.2 SNP rs34536443 Disease risk Positive
CYP2R1 Homo sapiens 11p15.2 SNP rs10766197 Disease risk Positive
CYP27B1 Homo sapiens 12q14.1 SNP rs10877012 Disease risk Negative
GAS5 Homo sapiens 1q25.1 SNP rs2067079 Disease risk Positive
MIR137 Homo sapiens 1p21.3 SNP rs1625579 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*1503 Disease risk Positive
HLA-DRB5 Homo sapiens 6p21.32 SNP DRB5*null Disease risk Positive
AGER Homo sapiens 6p21.32 SNP rs1035798 Disease risk Positive
AGER Homo sapiens 6p21.32 SNP rs2070600 Disease risk Positive
TBATAp Homo sapiens 10q22.1 SNP rs2791196 Disease risk Positive
TBATAp Homo sapiens 10q22.1 SNP rs2791196 Disease risk Positive
TBATAp Homo sapiens 10q22.1 SNP rs12221473 Disease risk Positive
HIF1A Homo sapiens 14q23.2 SNP rs11549465 Disease risk Negative
VEGFA Homo sapiens 6p21.1 SNP rs699947 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP DRB1*1501 Disease risk Positive
TNF Homo sapiens 6p21.33 Gene polymorphisms exon 10 nt 1668*T-->G Disease risk Positive
TNF Homo sapiens 6p21.33 Gene polymorphisms exon 6 nt 676*T-->G Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms exon 6 nt 783*G-->A Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms exon 10 nt 1663*G-->A Disease risk Negative
TNF Homo sapiens 6p21.33 Gene polymorphisms exon 10 nt 1690*T-->C Disease risk Negative
APOE Homo sapiens 19q13.32 Gene polymorphisms ε4 Disease risk Positive
IL1B Homo sapiens 2q14.1 Gene polymorphisms allele 2 of the Taq1 Disease risk Negative
IL1RN Homo sapiens 2q14.1 Gene polymorphisms allele 2 of VNTR locus Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs4646536 Disease risk Positive
CYP27B1 Homo sapiens 12q14.1 SNP rs10877012 Disease risk Positive
CYP27B1 Homo sapiens 12q14.1 SNP rs10877015 Disease risk Positive
CYP27B1 Homo sapiens 12q14.1 SNP rs703842 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 SNP rs3087243 Disease risk Positive
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF - 238 Disease risk Positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs1883832 Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs6074022 Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs1535045 Disease risk Negative
CD40 Homo sapiens 20q13.12 SNP rs11086998 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs7702920 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs41297577 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs41297579 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs9313422 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs34333511 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs1553316 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs12522248 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs1553318 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs2279804 Disease risk Negative
HAVCR1 Homo sapiens 5q33.3 SNP rs2277025 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs11574010 Disease risk Positive
CYP27B1 Homo sapiens 12q14.1 SNP rs10735810 Disease risk Negative
CYP27B1 Homo sapiens 12q14.1 SNP rs731236 Disease risk Negative
ICAM1 Homo sapiens 19p13.2 Gene polymorphisms ICAM1 AA Disease risk Positive
ICAM1 Homo sapiens 19p13.2 Gene polymorphisms ICAM1 AA Disease risk Positive
IFNAR1 Homo sapiens 21q22.11 SNP ref.27 Treatment risk Negative
IFNAR1 Homo sapiens 21q22.11 SNP rs1041429 Treatment risk Negative
IFNAR1 Homo sapiens 21q22.11 SNP rs1012334 Treatment risk Negative
IFNAR1 Homo sapiens 21q22.11 SNP rs1012335 Treatment risk Negative
IFNAR1 Homo sapiens 21q22.11 SNP rs2257167 Treatment risk Negative
IFNAR2 Homo sapiens 21q22.11 SNP rs3153 Treatment risk Negative
IFNAR2 Homo sapiens 21q22.11 SNP rs1051393 Treatment risk Negative
IFNAR2 Homo sapiens 21q22.11 SNP rs1131668 Treatment risk Negative
CASP9 Homo sapiens 1p36.21 Gene polymorphisms CASP9 G/G Disease risk Positive
RORA Homo sapiens 15q22.2 SNP rs4774388 Treatment risk Positive
RORA Homo sapiens 15q22.2 SNP rs11639084 Treatment risk Positive
DBP Homo sapiens 19q13.33 Gene polymorphisms codon 416 Disease risk Negative
DBP Homo sapiens 19q13.33 Gene polymorphisms codon 420 Disease risk Negative
IL4R Homo sapiens 16p12.1 Gene polymorphisms R551 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Gene polymorphisms DRB1*1501 Disease risk Positive
TNF Homo sapiens 6p21.33 Gene polymorphisms TNF-alpha -308 G/A Disease risk Positive
CYP27B1 Homo sapiens 12q14.1 Gene polymorphisms genotype bb Disease risk Positive
NGF Homo sapiens 1p13.2 SNP rs6330 Disease risk Positive
NGF Homo sapiens 1p13.2 SNP rs11102930 Disease risk Positive
NGF Homo sapiens 1p13.2 SNP rs7523831 Disease risk Negative
NGF Homo sapiens 1p13.2 SNP rs11102915 Disease risk Negative
NGF Homo sapiens 1p13.2 SNP rs6327 Disease risk Negative
NGF Homo sapiens 1p13.2 SNP rs2239622 Disease risk Negative
NGF Homo sapiens 1p13.2 SNP rs910330 Disease risk Negative
NGF Homo sapiens 1p13.2 SNP rs3811014 Disease risk Negative
NGF Homo sapiens 1p13.2 SNP rs17540656 Disease risk Negative
NGF Homo sapiens 1p13.2 SNP rs6673867 Disease risk Negative
CD24 Homo sapiens 6q21 SNP CD24V/V Disease risk Positive
CD24 Homo sapiens 6q21 SNP CD24A/V Disease risk Positive
CD24 Homo sapiens 6q21 SNP CD24A/A Disease risk Positive
ACE Homo sapiens 17q23.3 SNP DD genotype Disease risk Positive
STMN1 Homo sapiens 1p36.11 SNP rs182455 Disease risk Negative
NR3C1 Homo sapiens 5q31.3 Gene polymorphisms Haplotype 6 (TthIIII, ER2223EK, and 9beta-G Disease risk Positive
TNFAIP3 Homo sapiens 6q23.3 SNP rs10499194 Disease risk Positive
TNFAIP3 Homo sapiens 6q23.3 SNP rs6920220 Disease risk Positive
TNFAIP3 Homo sapiens 6q23.3 SNP rs5029939 Disease risk Positive
TNFAIP3 Homo sapiens 6q23.3 SNP rs6922466 Disease risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs1800693 Disease risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149584 Disease risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149577 Disease risk Positive
PHGDH Homo sapiens 1p12 SNP rs666930 Disease risk Positive
IRF8 Homo sapiens 16q24.1 SNP rs35929052 Disease risk Positive
FOXP3 Homo sapiens Xp11.23 SNP rs3761548 Disease risk Positive
HFE Homo sapiens 6p22.2 Gene polymorphisms C282Y Disease risk Negative
HFE Homo sapiens 6p22.2 Gene polymorphisms H63D Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 Gene polymorphisms DRB1*03 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Gene polymorphisms DRB1*15 Disease risk Positive
HLA-DRB3 Homo sapiens 6p21.3 Gene polymorphisms DRB3 Disease risk Positive
HLA-DRB5 Homo sapiens 6p21.32 Gene polymorphisms DRB5*0101 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Gene polymorphisms HLA-A*0301 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Gene polymorphisms HLA-A*0201 Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs1883832 Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs1535045 Disease risk Positive
KIF1B Homo sapiens 1p36.22 SNP rs3135388 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs2228570 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs1544410 Disease risk Positive
PON1 Homo sapiens 7q21.3 SNP rs662 Disease risk Negative
PON1 Homo sapiens 7q21.3 SNP rs854560 Disease risk Negative
PON1 Homo sapiens 7q21.3 SNP rs705381 Disease risk Negative
PON2 Homo sapiens 7q21.3 SNP rs6954345 Disease risk Negative
AGER Homo sapiens 6p21.32 SNP rs1800624 Disease risk Negative
AGER Homo sapiens 6p21.32 SNP rs1800625 Disease risk Positive
VDR Homo sapiens 12q13.11 Gene polymorphisms FokI Disease risk Negative
VDR Homo sapiens 12q13.11 Gene polymorphisms BsmI Disease risk Negative
VDR Homo sapiens 12q13.11 Gene polymorphisms TaqI Disease risk Negative
VDR Homo sapiens 12q13.11 Gene polymorphisms ApaI Disease risk Negative
CTLA4 Homo sapiens 2q33.2 Gene polymorphisms -318 C/T Disease risk Negative
CTLA4 Homo sapiens 2q33.2 Gene polymorphisms intergenic CT60 SNPs Disease risk Negative
CTLA4 Homo sapiens 2q33.2 Gene polymorphisms +49 A/G Disease risk Positive
CTLA4 Homo sapiens 2q33.2 Gene polymorphisms 3' UTR (AT(n)) Disease risk Positive
ESR1 Homo sapiens 6q25.1-q25.2 Gene polymorphisms PvuII Disease risk Negative
ESR1 Homo sapiens 6q25.1-q25.2 Gene polymorphisms XbaI Disease risk Negative
OAS1 Homo sapiens 12q24.13 SNP rs10774671 Disease risk Positive
OAS1 Homo sapiens 12q24.13 SNP rs3741981 Disease risk Positive
KIF1B Homo sapiens 1p36.22 SNP rs10492972 Disease risk Negative
CYP7A1 Homo sapiens 8q12.1 SNP rs3808607 Disease risk Negative
CYP7A1 Homo sapiens 8q12.1 SNP rs3824260 Disease risk Negative
CYP7A1 Homo sapiens 8q12.1 SNP -208G>C Disease risk Negative
NFKB1 Homo sapiens 4q24 Gene polymorphisms -94 ins/del ATTG promoter polymorphism Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs10735810 Disease risk Positive
MEFV Homo sapiens 16p13.3 Gene mutations M694V Disease risk Positive
MEFV Homo sapiens 16p13.3 Gene mutations M680I Disease risk Positive
MEFV Homo sapiens 16p13.3 Gene mutations V726A Disease risk Positive
MEFV Homo sapiens 16p13.3 Gene mutations E148Q Disease risk Positive
MEFV Homo sapiens 16p13.3 Gene mutations P369S Disease risk Positive
NFKBIL1 Homo sapiens 6p21.33 Gene polymorphisms exon 4 Disease risk Negative
HLA-G Homo sapiens 6p22.1 SNP —725C>G>T Disease risk Positive
HLA-G Homo sapiens 6p22.1 SNP —716>G>T Disease risk Negative
HLA-G Homo sapiens 6p22.1 indel N/A Disease risk Positive
IL2 Homo sapiens 4q27 polymorphisms The positionβ384 in the promoter region Disease risk Negative
IL2 Homo sapiens 4q27 polymorphisms The position +114 in the first exon Disease risk Negative
TLR9 Homo sapiens 3p21.2 SNP rs5743836 Disease risk Negative
TRIOBP Homo sapiens 22q13.1 SNP rs201693690 Disease risk Positive
FCGR2A Homo sapiens 1q23.3 Allele NA Disease risk Positive
CXCL8 Homo sapiens 4q13.3 SNP rs2227306 Disease risk Positive
BDNF Homo sapiens 11p14.1 SNP rs6265 Treatment risk Positive
IL23A Homo sapiens 12q13.3 SNP rs11209026 Disease risk Negative
IL23A Homo sapiens 12q13.3 SNP rs1004819 Disease risk Negative
STAT4 Homo sapiens 2q32.2-q32.3 Allele NA Disease risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149584 Disease risk Positive
AQP4 Homo sapiens 18q11.2 SNP NA Disease risk Negative
CNR1 Homo sapiens 6q15 Allele NA Treatment risk Positive
CD14 Homo sapiens 5q31.3 Allele NA Disease risk Positive
IL18 Homo sapiens 11q23.1 Allele NA Disease risk Positive
IL-27 Homo sapiens 16p12.1-p11.2 snp rs 153109 Disease risk Positive
IL-27 Homo sapiens 16p12.1-p11.2 snp rs 181206 Disease risk Positive
IL23A Homo sapiens 12q13.3 Allele NA Disease risk Positive
TNF Homo sapiens 6p21.33 SNP (rs1799964 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-A Homo sapiens 6p22.1 SNP rs9267649 Disease risk Positive
CYP24A1 Homo sapiens 20q13.2 SNP rs2248359 Disease risk Positive
CD24 Homo sapiens 6q21 SNP NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Alleles NA Disease risk Positive
APOE Homo sapiens 19q13.32 Alleles NA Disease risk Positive
MPO Homo sapiens 17q22 SNP NA Disease risk Positive
TRBV20OR9-2 Homo sapiens 9p13.3 restriction fragments length polymorphisms (RFLP) NA Disease risk Positive
ESR1 Homo sapiens 6q25.1-q25.2 Alleles NA Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 Alleles NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Alleles NA Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 Alleles NA Disease risk Positive
HLA-DQB2 Homo sapiens 6p21.32 Alleles NA Disease risk Positive
INPP4B Homo sapiens 4q31.21 SNP rs13102150 Disease risk Positive
IL1RN Homo sapiens 2q14.1 Alleles NA Disease risk Positive
EIF2B1 Homo sapiens 12q24.31 Allele NA Disease risk Negative
EIF2B5 Homo sapiens 3q27.1 SNP rs2971410 Disease risk Negative
EIF2B5 Homo sapiens 3q27.1 SNP rs2893756 Disease risk Negative
PTPRC Homo sapiens 1q31.3-q32.1 Allele NA Disease risk Negative
SYN3 Homo sapiens 22q12.3 SNP rs133946 Disease risk Negative
SYN3 Homo sapiens 22q12.3 SNP rs133945 Disease risk Negative
CYP2D6 Homo sapiens 22q13.2 Allele NA Disease risk Negative
Mbp Homo sapiens 18q23 Allele NA Disease risk Negative
CCL2 Homo sapiens 17q12 Allele NA Disease risk Negative
VMP1 Homo sapiens 17q23.1 SNP RS8070345 Phenotypic risk Positive
VMP1 Homo sapiens 17q23.1 SNP RS8070345 Disease risk Negative
APOE Homo sapiens 19q13.32 Allele NA Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Phenotypic risk Positive
MMP9 Homo sapiens 20q13.12 Allele NA Disease risk Negative
MMP2 Homo sapiens 16q12.2 Allele NA Disease risk Positive
IL-2R Homo sapiens 10p15.1 SNP rs2104286 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs1544410 Disease risk Negative
ESR1 Homo sapiens 6q25.1-q25.2 Allele NA Disease risk Positive
CCR5 Homo sapiens 3p21.31 Allele NA Disease risk Negative
CD1A Homo sapiens 1q23.1 Allele NA Disease risk Positive
CD1E Homo sapiens 1q23.1 Allele NA Disease risk Positive
CTLA4 Homo sapiens 2q33.2 Allele NA Disease risk Positive
TAGAP Homo sapiens 6q25.3 SNP rs1738074 Disease risk Positive
BDNF Homo sapiens 11p14.1 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388 Phenotypic risk Positive
CIITA Homo sapiens 16p13.13 SNP rs4774C Disease risk Positive
HLA-B Homo sapiens 6p21.33 Allele NA Disease risk Positive
STAT3 Homo sapiens 17q21.2 SNP rs744166 Disease risk Positive
STAT3 Homo sapiens 17q21.2 SNP rs2293152 Disease risk Negative
TNFRSF1A Homo sapiens 12p13.31 SNP Rs4149584 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs10877013 Disease risk Positive
CD14 Homo sapiens 5q31.3 Allele NA Disease risk Negative
CD14 Homo sapiens 5q31.3 Allele NA Disease risk Negative
NOTCH4 Homo sapiens 6p21.32 Allele NA Disease risk Negative
TNF Homo sapiens 6p21.33 Allele NA Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
CXCL16 Homo sapiens 17p13.2 Allele NA Disease risk Positive
IFIH1 Homo sapiens 2q24.2 SNP rs1990760 Disease risk Positive
GPC5 Homo sapiens 13q31.3 SNP rs10492503 Disease risk Positive
CD58 Homo sapiens 1p13.1 Allele NA Disease risk Positive
IRF8 Homo sapiens 16q24.1 SNP rs17445836 Disease risk Positive
IL23A Homo sapiens 12q13.3 SNP rs2066808 Disease risk Positive
IL23A Homo sapiens 12q13.3 SNP rs2371494 Disease risk Positive
IL23A Homo sapiens 12q13.3 SNP rs11575248 Disease risk Positive
IL23R Homo sapiens 1p31.3 SNP rs1884444 Disease risk Positive
IL10 Homo sapiens 1q32.1 Allele NA Disease risk Positive
TYK2 Homo sapiens 19p13.2 SNP rs55762744 Disease risk Positive
IFIH1 Homo sapiens 2q24.2 SNP rs1990760, Disease risk Positive
KCNH7 Homo sapiens 2q24.2 SNP rs2068330 Disease risk Positive
CIITA Homo sapiens 16p13.13 Allele NA Disease risk Positive
PRF1 Homo sapiens 10q22.1 SNP rs885822 Phenotypic risk Positive
PRF1 Homo sapiens 10q22.1 SNP rs10999426 Phenotypic risk Positive
PRF1 Homo sapiens 10q22.1 SNP rs3758562 Phenotypic risk Positive
GALR2 Homo sapiens 17q25.1 SNP rs61745847 up-regulation Phenotypic risk
LEP Homo sapiens 7q32.1 Allele NA Disease risk Positive
LEPR Homo sapiens 1p31.3 Allele NA Disease risk Positive
IL6 Homo sapiens 7p15.3 SNP rs1800795 Disease risk Positive
IL-12 Homo sapiens 5q33.3 SNP rs3212227 Disease risk Positive
FOXP3 Homo sapiens Xp11.23 SNP rs3761547 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Phenotypic risk Positive
LEP Homo sapiens 7q32.1 SNP rs7799039 Disease risk Positive
LEPR Homo sapiens 1p31.3 SNP rs1137101 Disease risk Positive
PPARGC1A Homo sapiens 4p15.2 SNP rs8192678 Disease risk Positive
MMP9 Homo sapiens 20q13.12 Allele NA Disease risk Negative
PLAU Homo sapiens 10q22.2 Allele NA Disease risk Negative
SERPINB2 Homo sapiens 18q21.33-q22.1 Allele NA Disease risk Negative
IL7 Homo sapiens 8q21.13 Allele NA Disease risk Positive
IL7R Homo sapiens 5p13.2 Allele NA Disease risk Positive
MMEL1 Homo sapiens 1p36.32 SNP rs3748816 Disease risk Positive
IRF5 Homo sapiens 7q32.1 Allele NA Disease risk Negative
IL7R Homo sapiens 5p13.2 Allele NA Treatment risk Positive
IL10 Homo sapiens 1q32.1 Allele NA Disease risk Negative
IL-12 Homo sapiens 5q33.3 Allele NA Disease risk Negative
TNF Homo sapiens 6p21.33 Allele NA Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
MMP2 Homo sapiens 16q12.2 Allele NA Disease risk Positive
IL1RL1 Homo sapiens 2q12.1 SNP rs1041973 Disease risk Positive
IL1RAP Homo sapiens 3q28 SNP rs4624606 Disease risk Negative
IL6 Homo sapiens 7p15.3 SNP rs1800795 Disease risk Negative
HTRA1 Homo sapiens 10q26.13 SNP rs11200638 Disease risk Negative
GFI1 Homo sapiens 1p22.1 SNP rs11804321 Disease risk Positive
GFI1 Homo sapiens 1p22.1 SNP rs11808092 Disease risk Positive
GFI1 Homo sapiens 1p22.1 SNP rs6680578 Disease risk Positive
NFKB1 Homo sapiens 4q24 Allele NA Disease risk Positive
RELA Homo sapiens 11q13.1 Allele NA Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs2903692 Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs6498169 Disease risk Positive
CLEC16A Homo sapiens 16p13.13 SNP rs6498169 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
APOE Homo sapiens 19q13.32 Allele NA Phenotypic risk Positive
MBP Homo sapiens 18q23 Allele NA Disease risk Negative
TGFB1 Homo sapiens 19q13.2 Allele NA Disease risk Positive
TGFBR2 Homo sapiens 3p24.1 Allele NA Disease risk Positive
IRF5 Homo sapiens 7q32.1 SNP rs2004640 Treatment risk Negative
IRF5 Homo sapiens 7q32.1 SNP rs3807306 Treatment risk Negative
IRF5 Homo sapiens 7q32.1 SNP rs4728142 Treatment risk Negative
IRF8 Homo sapiens 16q24.1 SNP rs13333054 Treatment risk Negative
IRF8 Homo sapiens 16q24.1 SNP rs17445836 Treatment risk Negative
GPC5 Homo sapiens 13q31.3 SNP rs10492503 Treatment risk Negative
CTLA-4 Homo sapiens 2q33.2 SNP NA Disease risk Negative
CXCL10 Homo sapiens 4q21.1 SNP rs3921 Disease risk Negative
CXCL10 Homo sapiens 4q21.1 SNP rs8878 Disease risk Negative
CXCL10 Homo sapiens 4q21.1 SNP rs3921 Treatment risk Positive
CXCL10 Homo sapiens 4q21.1 SNP rs8878 Treatment risk Positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs767455 Disease risk Negative
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149584 Disease risk Positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Positive
HLA-B Homo sapiens 6p21.33 Allele NA Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
CCL7 Homo sapiens 17q12 Allele NA Disease risk Positive
HLA-DMB Homo sapiens 6p21.32 Allele NA Disease risk Negative
HLA-DMA Homo sapiens 6p21.32 Allele NA Disease risk Negative
IL2 Homo sapiens 4q27 Allele NA Disease risk Positive
APOE Homo sapiens 19q13.32 Allele NA Disease risk Negative
PRNP Homo sapiens 20p13 SNP NA Disease risk Negative
TNF Homo sapiens 6p21.33 Allele NA Phenotypic risk Positive
HLA-A Homo sapiens 6p22.1 Allele NA Disease risk Negative
HLA-B Homo sapiens 6p21.33 Allele NA Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
TRB Homo sapiens 7q34 Allele NA Phenotypic risk Positive
NOD2 Homo sapiens 16q12.1 Allele NA Disease risk Negative
HLA-A Homo sapiens 6p22.1 Allele NA Disease risk Positive
HLA-C Homo sapiens 6p21.33 Allele NA Disease risk Positive
HLA-B Homo sapiens 6p21.33 Allele NA Disease risk Positive
HLA-DRA Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
GRM7 Homo sapiens 3p26.1 SNP rs779867 Disease risk Positive
GRM7 Homo sapiens 3p26.1 SNP rs6782011 Disease risk Negative
GRM7 Homo sapiens 3p26.1 SNP rs779867 Disease risk Negative
GRM7 Homo sapiens 3p26.1 SNP rs6782011 Disease risk Negative
LTA Homo sapiens 6p21.33 Allele NA Disease risk Positive
TNF Homo sapiens 6p21.33 Allele NA Disease risk Negative
CD226 Homo sapiens 18q22.2 SNP rs763361 Disease risk Positive
APOE Homo sapiens 19q13.32 Allele NA Disease risk Negative
HLA-DRA Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQA2 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-B Homo sapiens 6p21.33 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 amino acid polymorphisms NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs703842 Disease risk Positive
TGFB1 Homo sapiens 19q13.2 Allele NA Disease risk Negative
IL7R Homo sapiens 5p13.2 SNP NA Disease risk Positive
HLA-DQA1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
IGH Homo sapiens 14q32.33 Allele NA Disease risk Negative
CCR5 Homo sapiens 3p21.31 SNP rs333 Disease risk Negative
IL4 Homo sapiens 5q31.1 VNTR (variable number tandem repeat) 3 VNTR (variable number tandem repeat) Disease risk Positive
APOE Homo sapiens 19q13.32 Allele NA Phenotypic risk Positive
HLA-DPB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
CYP7A1 Homo sapiens 8q12.1 SNP rs3808607 Disease risk Negative
CYP46A1 Homo sapiens 14q32.2 SNP rs754203 Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
CTLA4 Homo sapiens N/A Allele NA Phenotypic risk Positive
APOE Homo sapiens 19q13.32 Allele NA Phenotypic risk Positive
CTLA4 Homo sapiens 2q33.2 Allele NA Disease risk Negative
PTPRC Homo sapiens 1q31.3-q32.1 SNP NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 amino acid polymorphisms NA Disease risk Positive
CTLA4 Homo sapiens 2q33.2 Allele NA Disease risk Negative
CNP Homo sapiens 17q21.2 Allele NA Disease risk Negative
NRG1 Homo sapiens 8p12 SNP rs77493513 Disease risk Positive
MIF Homo sapiens 22q11.23 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
IL6 Homo sapiens 7p15.3 Allele NA Treatment risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
HLA-DPA1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
IL1B Homo sapiens 2q14.1 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
CFB Homo sapiens 6p21.33 Allele NA Phenotypic risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388*A Disease risk Positive
TRB Homo sapiens 7q34 Allele NA Phenotypic risk Positive
TRA Homo sapiens 14q11.2 Allele NA Disease risk Positive
IL2 Homo sapiens 4q27 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
MIR196A2 Homo sapiens 12q13.13 SNP rs1 1614913 Disease risk Positive
TNFSF13B Homo sapiens 13q33.3 SNP rs7318477 Disease risk Positive
CCR5 Homo sapiens 3p21.31 Allele NA Phenotypic risk Positive
IL1B Homo sapiens IL-1; IL1F2; IL1beta; IL1-BETA SNP rs16944 Disease risk Negative
ICAM1 Homo sapiens 19p13.2 Allele NA Disease risk Positive
HLA-G Homo sapiens 6p22.1 Allele NA Disease risk Positive
ICAM1 Homo sapiens 19p13.2 Allele NA Disease risk Negative
ICAM1 Homo sapiens 19p13.2 SNP rs5498 Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388 Disease risk Positive
CD40 Homo sapiens 20q13.12 Allele NA Disease risk Negative
EIF2B1 Homo sapiens 12q24.31 Allele NA Disease risk Negative
ADA Homo sapiens 20q13.12 SNP rs244072 Disease risk Positive
SPP1 Homo sapiens 4q22.1 Allele NA Disease risk Negative
SPP1 Homo sapiens 4q22.1 Allele NA Phenotypic risk Positive
TNF Homo sapiens 6p21.33 Allele NA Disease risk Positive
CD58 Homo sapiens 1p13.1 SNP rs2300747G Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HAVCR2 Homo sapiens N/A SNP rs1036199 Disease risk Positive
HAVCR1 Homo sapiens N/A SNP rs7702919 Disease risk Negative
RGS7 Homo sapiens N/A Allele NA Disease risk Positive
HLA-A Homo sapiens 6p22.1 Allele NA Disease risk Positive
TRB Homo sapiens 7q34 Allele NA Phenotypic risk Positive
LOC102724971 Homo sapiens 15q11.2 Allele NA Phenotypic risk Positive
CYTH4 Homo sapiens 22q13.1 Allele NA Disease risk Positive
CCR2 Homo sapiens 3p21.31 SNP rs1799864 Disease risk Positive
IL32 Homo sapiens 16p13.3 Allele NA Disease risk Positive
CD24 Homo sapiens 6q21 Allele NA Disease risk Positive
BDNF Homo sapiens 11p14.1 SNP rs56164415 Disease risk Negative
HSPA4 Homo sapiens 5q31.1 SNP rs2227956 Disease risk Positive
CTLA4 Homo sapiens 2q33.2 Allele NA Disease risk Negative
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
TAP2 Homo sapiens 6p21.32 Allele NA Disease risk Negative
CTLA4 Homo sapiens 2q33.2 Allele NA Disease risk Negative
ADAMTS14 Homo sapiens 10q22.1 Allele NA Disease risk Positive
MBP Homo sapiens 18q23 Allele NA Disease risk Positive
IL7 Homo sapiens 8q21.13 Allele NA Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 Allele NA Disease risk Positive
TRBV20OR9-2 Homo sapiens 9p13.3 Allele NA Disease risk Positive
IL-1B Homo sapiens 2q14.1 Allele NA Disease risk Negative
IL1RN Homo sapiens 2q14.1 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
CHI3L1 Homo sapiens 1q32.1 SNP rs4950928 Disease risk Positive
GSTT1 Homo sapiens 22q11.23 Allele NA Disease risk Negative
GSTM1 Homo sapiens 1p13.3 Allele NA Disease risk Negative
CD24 Homo sapiens 6q21 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
HLA-DQA1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
HLA-DQB1 Homo sapiens 6p21.32 Allele NA Disease risk Negative
NOS2A Homo sapiens 17q11.2 Allele NA Disease risk Negative
OAS1 Homo sapiens 12q24.13 Allele NA Disease risk Positive
CD40 Homo sapiens 20q13.12 SNP rs1883832 Disease risk Positive
RAC2 Homo sapiens 22q13.1 Allele NA Disease risk Positive
VDR Homo sapiens 12q13.11 Allele NA Disease risk Negative
MMP9 Homo sapiens 20q13.12 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
HLA-A Homo sapiens 6p22.1 Allele NA Disease risk Positive
HLA-DRB1 Homo sapiens 6p21.32 Allele NA Disease risk Positive
FCRL3 Homo sapiens 1q23.1 SNP rs7528684 Disease risk Positive
FCRL3 Homo sapiens 1q23.1 SNP rs7522061 Disease risk Positive
FCRL3 Homo sapiens 1q23.1 SNP rs11264799 Disease risk Negative
LMNB1 Homo sapiens 5q23.2 Allele NA Disease risk Negative
MBP Homo sapiens 18q23 Allele NA Disease risk Negative
VDR Homo sapiens 12q13.11 SNP rs2228570 Disease risk Positive
VDR Homo sapiens 12q13.11 SNP rs7975232 N/A Negative
VDR Homo sapiens 12q13.11 SNP rs1544410 N/A Negative
VDR Homo sapiens 12q13.11 SNP rs11568820 N/A Negative
VDR Homo sapiens 12q13.11 SNP rs2228570 N/A Negative
VDR Homo sapiens 12q13.11 SNP rs731236 N/A Negative
IL7R Homo sapiens 5p13.2 SNP rs11567686 Phenotypic risk Positive
IL7R Homo sapiens 5p13.2 SNP rs11567685 Phenotypic risk Positive
IL7R Homo sapiens 5p13.2 SNP rs7718919 Phenotypic risk Positive
BDNF Homo sapiens 11p14.1 SNP rs6265 Disease risk positive
NLRP3 Homo sapiens 1q44 SNP rs3806265 Disease risk positive
NLRP3 Homo sapiens 1q44 SNP rs10754558 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk positive
GSTP1 Homo sapiens 11q13.2 SNP rs1695 N/A negative
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk positive
VDR Homo sapiens 12q13.11 SNP rs7975232 Disease risk positive
TLR3 Homo sapiens 4q35.1 SNP rs3775291 N/A negative
TLR3 Homo sapiens 4q35.1 insertion-deletion TLR3 [-/A](8) N/A N/A negative
HLA-G Homo sapiens 6p22.1 a 14 bp insertion / deletion in the untranslated exon 8 N/A N/A negative
HLA-G Homo sapiens 6p22.1 The -725 C/G exchange in the HLA-G promoter region N/A N/A negative
HLA-G Homo sapiens 6p22.1 HLA-G*0105N, a deletion that results in an irregular stopcodon in exon 3 N/A N/A negative
APOE Homo sapiens 19q13.32 SNP N/A N/A negative
CD80 Homo sapiens 3q13.33 transitions,deletion N/A N/A negative
ERV3-1 Homo sapiens 7q11.21 six single base pair variations and a drop-out of a nucleotide N/A N/A negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism N/A N/A negative
TRB Homo sapiens 7q34 polymorphism N/A N/A negative
HLA-DPB1 Homo sapiens 6p21.32 polymorphism N/A N/A negative
C3 Homo sapiens 19p13.3 polymorphism N/A Disease risk positive
P2RX7 Homo sapiens 12q24.31 SNP rs1718119 Disease risk positive
P2RX7 Homo sapiens 12q24.31 SNP rs22390912 Disease risk positive
ANKRD55 Homo sapiens 5q11.2 SNP rs6859219 Disease risk positive
MMEL1 Homo sapiens 1p36.32 SNP rs3748816 N/A negative
MANBA Homo sapiens 4q24 SNP rs7665090 Disease risk positive
L3MBTL3 Homo sapiens 6q23.1 SNP rs7740107 Disease risk positive
TNF Homo sapiens 6p21.33 SNP rs1800629 G/A Disease risk positive
IL18 Homo sapiens 11q23.1 SNP rs1946518 C/A Disease risk positive
IL16 Homo sapiens 15q25.1 SNP rs4072111 C/T N/A negative
IDO2 Homo sapiens 8p11.21 SNP rs10109853 N/A negative
IDO2 Homo sapiens 8p11.21 SNP rs4503083 N/A negative
RORA Homo sapiens 15q22.2 SNP rs11639048 Disease risk positive
RORA Homo sapiens 15q22.2 SNP rs4774388 Disease risk positive
CBS Homo sapiens 21q22.3 c.844_855ins68bp N/A Disease risk positive
RFC1 Homo sapiens 4p14 c.80G>A N/A Disease risk positive
GRIN1 Homo sapiens 9q34.3 SNP rs4880213 Disease risk positive
CASP8 Homo sapiens 2q33.1 SNP rs2037815 Disease risk positive
CASP8 Homo sapiens 2q33.1 SNP rs12990906 Disease risk positive
CASP8 Homo sapiens 2q33.1 SNP rs13113 Disease risk positive
MYO3B Homo sapiens 2q31.1 SNP N/A N/A negative
MYO3B Homo sapiens 2q31.1 SNP N/A N/A negative
VDR Homo sapiens 12q13.11 SNP rs10735810 N/A negative
APOE Homo sapiens 19q13.32 epsilon4 N/A N/A negative
HLA-DRB1 Homo sapiens 6p21.32 DRB 1" 1501 N/A Disease risk positive
FOXO3 Homo sapiens 6q21 SNP rs2253310 Disease risk positive
FOXO3 Homo sapiens 6q21 SNP rs4966936 Disease risk positive
FOXO1 Homo sapiens 13q14.11 SNP rs3900833 Disease risk positive
IL12B Homo sapiens 5q33.3 SNP rs17860508 Disease risk positive
IL12B Homo sapiens 5q33.3 SNP rs3212227 Disease risk positive
EVI5 Homo sapiens 1p22.1 SNP rs6680578 N/A negative
EVI5 Homo sapiens 1p22.1 SNP rs11810217 N/A negative
PDCD1 Homo sapiens 2q37.3 SNP rs11568821 Disease risk positive
PDCD1 Homo sapiens 2q37.3 SNP rs2227981 Disease risk positive
PDCD1 Homo sapiens 2q37.3 SNP rs2227982 Disease risk positive
ERAP1 Homo sapiens 5q15 SNP rs30187 Disease risk positive
GRN Homo sapiens 17q21.31 SNP rs2879096 Disease risk positive
CIITA Homo sapiens 16p13.13 SNP rs4774 Disease risk positive
SPARCL1 Homo sapiens 4q22.1 SNP rs1049539 N/A negative
SPARCL1 Homo sapiens 4q22.1 SNP rs1049544 N/A negative
SPARCL1 Homo sapiens 4q22.1 SNP rs1130643 N/A negative
HLA-DRB1 Homo sapiens 6p21.32 DRB1*15:01 allele N/A Disease risk positive
PLCG2 Homo sapiens 16q23.3 SNP rs72824905 Disease risk positive
HTR2A Homo sapiens 13q14.2 DNA methylation N/A Disease risk positive
CD33 Homo sapiens 19q13.41 SNP rs3865444 Disease risk positive
CD58 Homo sapiens 1p13.1 SNP rs1414273 Disease risk positive
AHI1 Homo sapiens 6q23.3 SNP rs11154801 Disease risk positive
VDR Homo sapiens 12q13.11 SNP rs7975232 N/A negative
VDR Homo sapiens 12q13.11 SNP rs731236 Disease risk positive
TNFRSF1A Homo sapiens 12p13.31 SNP rs1800693 Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 allele N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 HLA-DRB1 *0801 allele N/A Disease risk positive
APOE Homo sapiens 19q13.32 epsilon-4 allele N/A N/A negative
CCR5 Homo sapiens 3p21.31 deletion N/A Disease risk positive
CTLA4 Homo sapiens 2q33.2 SNP rs3087243 Disease risk positive
CCR5 Homo sapiens 3p21.31 A 32-bp deletion in the CCR5 N/A Disease risk positive
MAG Homo sapiens 19q13.12 SNP N/A N/A negative
SH2D2A Homo sapiens 1q23.1 SH2D2A GA repeat N/A N/A negative
HLA-DRB1 Homo sapiens 6p21.32 HLA-DR15 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 DRB1*1501 N/A Disease risk positive
HLA-DQA1 Homo sapiens 6p21.32 DQA1*0102 N/A Disease risk positive
HLA-DQB1 Homo sapiens 6p21.32 DQB1*0602 N/A Disease risk positive
HRES1 Homo sapiens 1q42 allelic N/A Disease risk positive
TAP1 Homo sapiens 6p21.32 dimorphisms N/A Disease risk positive
TAP2 Homo sapiens 6p21.32 dimorphisms N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 DRB5 * 0101 N/A Disease risk positive
HLA-DQB1 Homo sapiens 6p21.32 DQB1*0602 N/A Disease risk positive
HLA-DQA1 Homo sapiens 6p21.32 DQA1*0102 N/A Disease risk positive
HLA-DPB1 Homo sapiens 6p21.32 HLA-DP β N/A N/A negative
LRP2 Homo sapiens 2q31.1 SNP rs12988804 Disease risk positive
SIRPG Homo sapiens 20p13 SNP rs2281808 Disease risk positive
C3 Homo sapiens 19p13.3 SNP rs2230199 Disease risk positive
MIR155 Homo sapiens 21q21.3 SNP rs767649 N/A negative
MIR196A2 Homo sapiens 12q13.13 SNP rs11614913 N/A negative
VDR Homo sapiens 12q13.11 FokI ff N/A Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs201084372 Disease risk positive
IL12B Homo sapiens 5q33.3 SNP rs6887695 Disease risk positive
CSGALNACT1 Homo sapiens 8p21.3 cSNP rs140161612 N/A negative
ACE Homo sapiens 17q23.3 ACE homozygotes, II N/A Disease risk positive
ACE Homo sapiens 17q23.3 ACE homozygotes,DD N/A Disease risk positive
ACE Homo sapiens 17q23.3 AT1R 1166A/C N/A N/A negative
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk positive
CIITA Homo sapiens 16p13.13 SNP rs4774 * C Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 HLA-DRB1*15:01 N/A Disease risk positive
WT1 Homo sapiens 11p13 SNP rs10767935 Disease risk positive
WT1 Homo sapiens 11p13 SNP rs5030244 Disease risk positive
NQO1 Homo sapiens 16q22.1 SNP rs1800566 N/A negative
CD226 Homo sapiens 18q22.2 SNP rs1788229 N/A negative
CD226 Homo sapiens 18q22.2 SNP rs763361 N/A negative
HLA-DQB1 Homo sapiens 6p21.32 DQB1*0303 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 HLA-DRB1 * 04 / * 07 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 HLA-DRB1*09 (DR53) N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 DRB1*15 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 *16 (DR51) N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 *08 (DR8) N/A Disease risk positive
STAT3 Homo sapiens 17q21.2 SNP rs744166 Disease risk positive
CTLA4 Homo sapiens 2q33.2 CT60A/G N/A Disease risk positive
CTLA4 Homo sapiens 2q33.2 Jo31G/T N/A Disease risk positive
CTLA4 Homo sapiens 2q33.2 CTLA-4-319C/T N/A Disease risk positive
CTLA4 Homo sapiens 2q33.2 (AT)n repeat N/A Disease risk positive
BTG1 Homo sapiens 12q21.33 SNP rs731652 Disease risk positive
TNFRSF1A Homo sapiens 12p13.31 R92Q N/A Disease risk positive
DLG5 Homo sapiens 10q22.3 SNP rs1248696 N/A negative
HLA-DRB1 Homo sapiens 6p21.32 SNP rs2076530 N/A negative
UCP2 Homo sapiens 11q13.4 UCP2-866G N/A Disease risk positive
PTPRC Homo sapiens 1q31.3-q32.1 C77G N/A N/A negative
IFNGR2 Homo sapiens 21q22.11 IFNGR2*Arg64 N/A Disease risk positive
APOE Homo sapiens 19q13.32 epsilon4 N/A Disease risk positive
FCGR2A Homo sapiens 1q23.3 allele N/A N/A negative
FCGR3B Homo sapiens 1q23.3 allele N/A N/A negative
CTLA4 Homo sapiens 2q33.2 intragenic polymorphisms N/A Disease risk positive
TAP2 Homo sapiens 6p21.32 locus N/A N/A negative
IL7R Homo sapiens 5p13.2 SNP rs987107 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs3194051 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs1494571 Disease risk positive
CD40 Homo sapiens 20q13.12 SNP rs1883832 Disease risk positive
CD40 Homo sapiens 20q13.12 SNP rs6074022 Disease risk positive
CNR2 Homo sapiens 1p36.11 SNP rs35761398 Disease risk positive
GTF2I Homo sapiens 7q11.23 SNP rs117026326 N/A negative
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk positive
IL2RA Homo sapiens 10p15.1 SNP rs12722489 Disease risk positive
CXCR5 Homo sapiens 11q23.3 SNP rs3922 N/A negative
FTO Homo sapiens 16q12.2 SNP rs9939609 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs11567685 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 N/A negative
IL18 Homo sapiens 11q23.1 SNP rs187238 Disease risk positive
KIR2DL1 Homo sapiens 19q13.42 N/A N/A Disease risk positive
HLA-B Homo sapiens 6p21.33 HLA-Bw4 N/A Disease risk positive
IL2RA Homo sapiens 10p15.1 SNP rs2104286 Disease risk positive
IL2RA Homo sapiens 10p15.1 SNP rs11594656 Disease risk positive
LILRA3 Homo sapiens 19q13.4 deletion N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 SNP rs3135388 Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 HLA-DRB1(*)0406 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 DRB1(*)1302, DRB1(*)120201 and DPB1(*)2101 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 DRB1(*)120201 and DPB1(*)2101 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 DPB1(*)2101 N/A Disease risk positive
UCP2 Homo sapiens 11q13.4 SNP rs660339 Disease risk positive
CD24 Homo sapiens 6q21 Ala/Val N/A N/A negative
SLC11A1 Homo sapiens 2q35 5'GT repeat N/A N/A negative
SLC11A1 Homo sapiens 2q35 D543N N/A N/A negative
SLC11A1 Homo sapiens 2q35 1729 + 55del4 N/A N/A negative
SLC11A1 Homo sapiens 2q35 1729 + 271del4 N/A N/A negative
APOE Homo sapiens 19q13.32 epsilon4 N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 HLA-DRB1*15 N/A N/A negative
ICAM1 Homo sapiens 19p13.2 Exon 4 and exon 6 N/A N/A negative
MBP Homo sapiens 18q23 1445 bp N/A N/A negative
Ace Homo sapiens 11 E1; 11 68.84 cM SNP rs1799752 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs11567685 Disease risk positive
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk positive
CD6 Homo sapiens 11q12.2 SNP rs11230563 Disease risk positive
CLEC16A Homo sapiens 16p13.13 SNP rs12708716 Disease risk positive
CLEC16A Homo sapiens 16p13.13 SNP rs6498169 Disease risk positive
EVI5 Homo sapiens 1p22.1 SNP rs10735781 Disease risk positive
EVI5 Homo sapiens 1p22.1 SNP rs6680578 Disease risk positive
GPC5 Homo sapiens 13q31.3 SNP rs553717 Disease risk positive
TYK2 Homo sapiens 19p13.2 SNP rs34536443 Disease risk positive
EBF1 Homo sapiens 5q33.3 SNP rs1368297 Disease risk positive
HLA-DPB1 Homo sapiens 6p21.32 N/A HLA-DPB1*0501 Disease risk positive
CCL2 Homo sapiens 17q12 SNP rs1024611 Disease risk we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD
CCL2 Homo sapiens 17q12 SNP rs2857656 Disease risk we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD
CCL2 Homo sapiens 17q12 SNP rs28730833 Disease risk we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD
CCL2 Homo sapiens 17q12 SNP rs3917887 Disease risk we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD
CCL2 Homo sapiens 17q12 SNP rs2857657 Disease risk we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD
CCL2 Homo sapiens 17q12 SNP rs4586 Disease risk we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD
CCL2 Homo sapiens 17q12 SNP rs13900 Disease risk we did not find any association, which was consistent with other studies in Caucasian populations. In conclusion, our results suggest that CCL2 variants may not contribute to the pathogenesis of IDD
TNFRSF1A Homo sapiens 12p13.31 SNP rs4149584 Disease risk our results provide support for a sex‐ and HLA‐DRB1*15:01‐independent association of TNFRSF1A rs1800693 SNP with MS susceptibility, but not with age at disease onset, severity or rate of disability accumulation
TNFRSF1A Homo sapiens 12p13.31 SNP rs1800693 Disease risk our results provide support for a sex‐ and HLA‐DRB1*15:01‐independent association of TNFRSF1A rs1800693 SNP with MS susceptibility, but not with age at disease onset, severity or rate of disability accumulation
GC Homo sapiens 4q13.3 gene polymorphisms N/A Disease risk While MP therapy during pregnancy is considered relatively save for the fetus, it may be detrimental for later cognitive and neuropsychiatric function. The underlying mechanism is thought to be an epigenetically mediated desensitization of GC receptors, the subsequent increase in stress sensitivity, and a GC-mediated impairment of brain development.
TGFB3 Homo sapiens 14q24.3 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
FGF2 Homo sapiens 4q28.1 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
FGFR2 Homo sapiens 10q26.13 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
FGFR3 Homo sapiens 4p16.3 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
PDGFA Homo sapiens 7p22.3 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
IGF1R Homo sapiens 15q26.3 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
TRK-C Homo sapiens 15q25.3 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
NRG1 Homo sapiens 8p12 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
EGFR Homo sapiens 7p11.2 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
ERBB2 Homo sapiens 17q12 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
NR5A1 Homo sapiens 9q33.3 gene polymorphisms N/A Disease risk TGFP3, the only gene highlighted by this study, deserves further analysis
HLA-DRB1 Homo sapiens 6p21.32 gene polymorphisms N/A Disease risk Thus, the contribution of HLA class II to the pathogenesis of MS is not mediated by allele-overlapping antigen binding sites, but is confined to the disease associated HLA allele
CD4 Homo sapiens 12p13.31 SNP rs7957426 Disease risk Three SNPs (rs3782736, rs7957426, rs10774450) showed association at the 5% significance level
CD4 Homo sapiens 12p13.31 SNP rs10774450 Disease risk Three SNPs (rs3782736, rs7957426, rs10774450) showed association at the 5% significance level
CD4 Homo sapiens 12p13.31 SNP rs3782736 Disease risk Three SNPs (rs3782736, rs7957426, rs10774450) showed association at the 5% significance level
CCL14 Homo sapiens 17q12 SNP rs854680 Disease risk this study reveals strong associations with a marker and a haplotype encompassing the CCL14 gene, which suggests that a lupus relevant variant may lie within or in the proximity of this haplotype
CCL14 Homo sapiens 17q12 SNP rs16971802 Disease risk this study reveals strong associations with a marker and a haplotype encompassing the CCL14 gene, which suggests that a lupus relevant variant may lie within or in the proximity of this haplotype
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk resulting in stronger association with similar OR (P 1.9 β 10E29). These findings in our sample support previous reported association studies between IL7RA rs6897932 and MS
GPC1 Homo sapiens 2q37.3 SNP rs9523787 Disease risk An intronic SNP in the Glypican-5 gene (rs9523787) showed association with MS (pcorr= 0.006)
GPC1 Homo sapiens 2q37.3 SNP rs7333912 Disease risk An intronic SNP in the Glypican-5 gene (rs9523787) showed association with MS (pcorr= 0.006)
GPC1 Homo sapiens 2q37.3 SNP rs17267815 Disease risk An intronic SNP in the Glypican-5 gene (rs9523787) showed association with MS (pcorr= 0.006)
GPC1 Homo sapiens 2q37.3 SNP rs12876985 Disease risk An intronic SNP in the Glypican-5 gene (rs9523787) showed association with MS (pcorr= 0.006)
IRF5 Homo sapiens 7q32.1 SNP rs4728142 Disease risk Additionally, trends for association were observed between rs3807306T and infection with HHV-6 [p 0.05, OR (95% CI) 1.56 (1.00–2.44)] and response to IFN-b therapy [P 0.09, OR (95% CI) 1.39 (0.95–2.05)].
IRF5 Homo sapiens 7q32.1 SNP rs3807306 Disease risk Additionally, trends for association were observed between rs3807306T and infection with HHV-6 [p 0.05, OR (95% CI) 1.56 (1.00–2.44)] and response to IFN-b therapy [P 0.09, OR (95% CI) 1.39 (0.95–2.05)].
PCK1 Homo sapiens 20q13.31 SNP rs8192708G Disease risk MS subjects were genotyped for five single nucleotide polymorphisms (SNPs) associated with susceptibility to AD: PICALM, CR1, CLU, PCK1, and ZNF224. We assessed brain volume using Brain Parenchymal Fraction (BPF) measurements obtained from Magnetic Resonance Imaging (MRI) data and cognitive function using the Symbol Digit Modalities Test (SDMT). Genotypes were correlated with cross-sectional BPF and SDMT scores using linear regression after adjusting for sex, age at symptom onset, and disease duration. 722 MS patients with a mean (6SD) age at enrollment of 41 (610) years were followed for 44 (628) months. The AD risk-associated allele of a non-synonymous SNP in the PCK1 locus (rs8192708G ) is associated with a smaller average brain volume (P = 0.0047) at the baseline MRI, but it does not impact our baseline estimate of cognition. PCK1 is additionally associated with higher baseline T2-hyperintense lesion volume (P = 0.0088). Finally, we provide technical validation of our observation in a subset of 641 subjects that have more than one MRI study, demonstrating the same association between PCK1 and smaller average brain volume (P = 0.0089) at the last MRI visit
PICALM Homo sapiens 11q14.2 SNP rs3851179 Disease risk MS subjects were genotyped for five single nucleotide polymorphisms (SNPs) associated with susceptibility to AD: PICALM, CR1, CLU, PCK1, and ZNF224. We assessed brain volume using Brain Parenchymal Fraction (BPF) measurements obtained from Magnetic Resonance Imaging (MRI) data and cognitive function using the Symbol Digit Modalities Test (SDMT). Genotypes were correlated with cross-sectional BPF and SDMT scores using linear regression after adjusting for sex, age at symptom onset, and disease duration. 722 MS patients with a mean (6SD) age at enrollment of 41 (610) years were followed for 44 (628) months. The AD risk-associated allele of a non-synonymous SNP in the PCK1 locus (rs8192708G ) is associated with a smaller average brain volume (P = 0.0047) at the baseline MRI, but it does not impact our baseline estimate of cognition. PCK1 is additionally associated with higher baseline T2-hyperintense lesion volume (P = 0.0088). Finally, we provide technical validation of our observation in a subset of 641 subjects that have more than one MRI study, demonstrating the same association between PCK1 and smaller average brain volume (P = 0.0089) at the last MRI visit
CR1 Homo sapiens 1q32.2 SNP rs6656401 Disease risk MS subjects were genotyped for five single nucleotide polymorphisms (SNPs) associated with susceptibility to AD: PICALM, CR1, CLU, PCK1, and ZNF224. We assessed brain volume using Brain Parenchymal Fraction (BPF) measurements obtained from Magnetic Resonance Imaging (MRI) data and cognitive function using the Symbol Digit Modalities Test (SDMT). Genotypes were correlated with cross-sectional BPF and SDMT scores using linear regression after adjusting for sex, age at symptom onset, and disease duration. 722 MS patients with a mean (6SD) age at enrollment of 41 (610) years were followed for 44 (628) months. The AD risk-associated allele of a non-synonymous SNP in the PCK1 locus (rs8192708G ) is associated with a smaller average brain volume (P = 0.0047) at the baseline MRI, but it does not impact our baseline estimate of cognition. PCK1 is additionally associated with higher baseline T2-hyperintense lesion volume (P = 0.0088). Finally, we provide technical validation of our observation in a subset of 641 subjects that have more than one MRI study, demonstrating the same association between PCK1 and smaller average brain volume (P = 0.0089) at the last MRI visit
CLU Homo sapiens 8p21.1 SNP rs11136000 Disease risk MS subjects were genotyped for five single nucleotide polymorphisms (SNPs) associated with susceptibility to AD: PICALM, CR1, CLU, PCK1, and ZNF224. We assessed brain volume using Brain Parenchymal Fraction (BPF) measurements obtained from Magnetic Resonance Imaging (MRI) data and cognitive function using the Symbol Digit Modalities Test (SDMT). Genotypes were correlated with cross-sectional BPF and SDMT scores using linear regression after adjusting for sex, age at symptom onset, and disease duration. 722 MS patients with a mean (6SD) age at enrollment of 41 (610) years were followed for 44 (628) months. The AD risk-associated allele of a non-synonymous SNP in the PCK1 locus (rs8192708G ) is associated with a smaller average brain volume (P = 0.0047) at the baseline MRI, but it does not impact our baseline estimate of cognition. PCK1 is additionally associated with higher baseline T2-hyperintense lesion volume (P = 0.0088). Finally, we provide technical validation of our observation in a subset of 641 subjects that have more than one MRI study, demonstrating the same association between PCK1 and smaller average brain volume (P = 0.0089) at the last MRI visit
ZNF224 Homo sapiens 19q13.31 SNP rs3746319 Disease risk MS subjects were genotyped for five single nucleotide polymorphisms (SNPs) associated with susceptibility to AD: PICALM, CR1, CLU, PCK1, and ZNF224. We assessed brain volume using Brain Parenchymal Fraction (BPF) measurements obtained from Magnetic Resonance Imaging (MRI) data and cognitive function using the Symbol Digit Modalities Test (SDMT). Genotypes were correlated with cross-sectional BPF and SDMT scores using linear regression after adjusting for sex, age at symptom onset, and disease duration. 722 MS patients with a mean (6SD) age at enrollment of 41 (610) years were followed for 44 (628) months. The AD risk-associated allele of a non-synonymous SNP in the PCK1 locus (rs8192708G ) is associated with a smaller average brain volume (P = 0.0047) at the baseline MRI, but it does not impact our baseline estimate of cognition. PCK1 is additionally associated with higher baseline T2-hyperintense lesion volume (P = 0.0088). Finally, we provide technical validation of our observation in a subset of 641 subjects that have more than one MRI study, demonstrating the same association between PCK1 and smaller average brain volume (P = 0.0089) at the last MRI visit
MERTK Homo sapiens 2q13 SNP rs867311 Disease risk All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility
MERTK Homo sapiens 2q13 SNP rs12477716 Disease risk All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility
MERTK Homo sapiens 2q13 SNP rs17835605 Disease risk All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility
MERTK Homo sapiens 2q13 SNP rs4278932 Disease risk All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility
MERTK Homo sapiens 2q13 SNP rs4528767 Disease risk All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility
MERTK Homo sapiens 2q13 SNP rs17174870 Disease risk All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility
MERTK Homo sapiens 2q13 SNP rs1516629 Disease risk All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility
IRF5 Homo sapiens 7q32.1 SNP rs2004640-TT Disease risk The clinical relevance of the rs2004640-TT genotype was validated in an independent cohort wherein a shorter time to first relapse was found (P 0.037). These findings suggest a role for IRF5 gene variation in the pharmacological and clinical outcome of IFNb therapy that might have relevance as biomarker to predict the response to IFNb in multiple sclerosis
IRF5 Homo sapiens 7q32.1 SNP rs47281420-AA Disease risk The clinical relevance of the rs2004640-TT genotype was validated in an independent cohort wherein a shorter time to first relapse was found (P 0.037). These findings suggest a role for IRF5 gene variation in the pharmacological and clinical outcome of IFNb therapy that might have relevance as biomarker to predict the response to IFNb in multiple sclerosis
IRF5 Homo sapiens 7q32.1 SNP rs4728142-AA Disease risk The clinical relevance of the rs2004640-TT genotype was validated in an independent cohort wherein a shorter time to first relapse was found (P 0.037). These findings suggest a role for IRF5 gene variation in the pharmacological and clinical outcome of IFNb therapy that might have relevance as biomarker to predict the response to IFNb in multiple sclerosis
USP18 Homo sapiens 22q11.21 SNP rs2542109 Disease risk Altogether, these results point to a role of USP18 in MS pathogenesis and the therapeutic response to IFNb.
USP18 Homo sapiens 22q11.21 SNP rs9618216 Disease risk Altogether, these results point to a role of USP18 in MS pathogenesis and the therapeutic response to IFNb.
MMP9 Homo sapiens 20q13.12 SNP rs6073751 Disease risk We determined the first five axes of variation resulting from a multidimensional scaling analysis (MDS) of the identity by state (IBS) matrix. These were used as covariates in the analysis, thereby taking population stratification into account. SNPs with a minor allele frequency (MAF) b0.01, a call rate b98%, or a significant deviation from Hardy–Weinberg-Equilibrium
MMP9 Homo sapiens 20q13.12 SNP rs3918242 Disease risk We determined the first five axes of variation resulting from a multidimensional scaling analysis (MDS) of the identity by state (IBS) matrix. These were used as covariates in the analysis, thereby taking population stratification into account. SNPs with a minor allele frequency (MAF) b0.01, a call rate b98%, or a significant deviation from Hardy–Weinberg-Equilibrium
MTHFR Homo sapiens 1p36.22 SNP rs1801133 Disease risk In our study, we observed that the frequency of the T/T genotype for the MTHFR C[677]T polymorphism was significantly higher in patients than in controls (p = 0.04, OR: 3.16, 95% CI: 1.23-8.17).Though for the MTHFR A[1298]C polymorphism, the A/A genotype was more frequent in controls than in patients (41.3% vs. 32.5%, p = 0.04). Similarly to previous studies, we found a possible link between an increased risk of MS and the MTHFR C[677]T polymorphism and a decreased risk (protective effects) of MS and the MTHFR A[1298]C polymorphism
MTHFR Homo sapiens 1p36.22 SNP rs1801131 Disease risk In our study, we observed that the frequency of the T/T genotype for the MTHFR C[677]T polymorphism was significantly higher in patients than in controls (p = 0.04, OR: 3.16, 95% CI: 1.23-8.17).Though for the MTHFR A[1298]C polymorphism, the A/A genotype was more frequent in controls than in patients (41.3% vs. 32.5%, p = 0.04). Similarly to previous studies, we found a possible link between an increased risk of MS and the MTHFR C[677]T polymorphism and a decreased risk (protective effects) of MS and the MTHFR A[1298]C polymorphism
MTHFR Homo sapiens 1p36.22 SNP rs1805087 Disease risk In our study, we observed that the frequency of the T/T genotype for the MTHFR C[677]T polymorphism was significantly higher in patients than in controls (p = 0.04, OR: 3.16, 95% CI: 1.23-8.17).Though for the MTHFR A[1298]C polymorphism, the A/A genotype was more frequent in controls than in patients (41.3% vs. 32.5%, p = 0.04). Similarly to previous studies, we found a possible link between an increased risk of MS and the MTHFR C[677]T polymorphism and a decreased risk (protective effects) of MS and the MTHFR A[1298]C polymorphism
MTHFR Homo sapiens 1p36.22 SNP rs1801394 Disease risk In our study, we observed that the frequency of the T/T genotype for the MTHFR C[677]T polymorphism was significantly higher in patients than in controls (p = 0.04, OR: 3.16, 95% CI: 1.23-8.17).Though for the MTHFR A[1298]C polymorphism, the A/A genotype was more frequent in controls than in patients (41.3% vs. 32.5%, p = 0.04). Similarly to previous studies, we found a possible link between an increased risk of MS and the MTHFR C[677]T polymorphism and a decreased risk (protective effects) of MS and the MTHFR A[1298]C polymorphism
MBP Homo sapiens 18q23 SNP rs12959006 Disease risk Lymphocyte activation measured by CD69 expression was also analyzed according to sex and rs12959006 genotype. The rs12959006 polymorphism contributed significantly to a higher number of relapses at 5 years after onset only in male patients (rs12959006TT β = 0.74 [0.36–1.09]; p = 7 × 105 ). Titers of anti-HHV6 IgG antibodies showed also a mild association with relapses, both in male and female patients (β = 0.01 [0.01–0.02]; p = 3.7 × 108 ). Both the genetic variation in MBP and HHV-6 infection aid in predicting a higher number of relapses during the first years of MS. The association described in MBP rs12959006T is exclusive to male patients
PTPRC Homo sapiens 1q31.3-q32.1 SNP polymorphism Disease risk We further show that populations living in the Pamir mountains of Central Asia have a very high prevalence of the C77G variant
APOE Homo sapiens 19q13.32 gene polymorphisms N/A Disease risk The frequency of E4 allele as a genetic risk factor for some multifactorial diseases in the population of Southern Iran is in the lowest reported amounts in the world. Iranian population has Caucasoid origin but differs from some Caucasian populations in Europe and America
TOR1A Homo sapiens 9q34.11 SNP rs2395182, Disease risk Our results show that this tag SNP method is very accurate and provides an excellent basis for population screening for CD
TOR1A Homo sapiens 9q34.11 SNP rs7775228 Disease risk Our results show that this tag SNP method is very accurate and provides an excellent basis for population screening for CD
TOR1A Homo sapiens 9q34.11 SNP rs2187668 Disease risk Our results show that this tag SNP method is very accurate and provides an excellent basis for population screening for CD
TOR1A Homo sapiens 9q34.11 SNP rs4639334 Disease risk Our results show that this tag SNP method is very accurate and provides an excellent basis for population screening for CD
TOR1A Homo sapiens 9q34.11 SNP rs7454108 Disease risk Our results show that this tag SNP method is very accurate and provides an excellent basis for population screening for CD
TOR1A Homo sapiens 9q34.11 SNP rs4713586 Disease risk Our results show that this tag SNP method is very accurate and provides an excellent basis for population screening for CD
CIITA Homo sapiens 16p13.13 SNP rs3087456 Disease risk We thus conclude that previous findings with regard to the role of the CIITA -168AG SNP in autoimmunity may have to be reconsidered
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk This suggests that rs6897932 is not associated with general inflammation, and the reported associations between the T-allele in rs6897932 with several autoimmune diseases may be mediated through effects on a restricted part of the immune system
AQP4 Homo sapiens 18q11.2 SNP rs1839318 Disease risk Although it is possible that the mutations contributed to an increased risk of inflammatory central nervous system disease in these individuals, it is unlikely that mutations are a significant contributor to most patients with NMO spectrum disorders in China
AQP4 Homo sapiens 18q11.2 SNP rs72557968 Disease risk Although it is possible that the mutations contributed to an increased risk of inflammatory central nervous system disease in these individuals, it is unlikely that mutations are a significant contributor to most patients with NMO spectrum disorders in China
STAT4 Homo sapiens 2q32.2-q32.3 SNP rs7574865 Disease risk The results of multiple test comparisons were corrected using the Benjamini and Hochberg false discovery rate (FDR–BH). After correcting for multiple test comparisons, the minor alleles of four STAT4 SNPs exhibited significant association with increased risk of NMOSD (rs7574865 T, odds ratio [OR] = 1.66, 95% confidence interval [CI] 1.32–2.08, Pcorr = 0.000; rs10181656 G, OR = 1.62, 95% CI 1.29–2.03, Pcorr = 0.000; rs10168266 T, OR = 1.59, 95% CI 1.27–2.00, Pcorr = 0.001; and rs13426947 A, OR = 1.51, 95% CI 1.21–1.90, Pcorr = 0.004). Identical results were observed in the dominant, recessive, and additive models. In contrast, the G allele of rs7601754 displayed a protective effect against NMOSD (OR = 0.53, 95% CI 0.36–0.76, Pcorr = 0.006). Our study indicates that STAT4 polymorphisms are associated with the risk of NMOSD, which provides novel insights into the underlying mechanisms of this disease
STAT4 Homo sapiens 2q32.2-q32.3 SNP rs10181656 Disease risk The results of multiple test comparisons were corrected using the Benjamini and Hochberg false discovery rate (FDR–BH). After correcting for multiple test comparisons, the minor alleles of four STAT4 SNPs exhibited significant association with increased risk of NMOSD (rs7574865 T, odds ratio [OR] = 1.66, 95% confidence interval [CI] 1.32–2.08, Pcorr = 0.000; rs10181656 G, OR = 1.62, 95% CI 1.29–2.03, Pcorr = 0.000; rs10168266 T, OR = 1.59, 95% CI 1.27–2.00, Pcorr = 0.001; and rs13426947 A, OR = 1.51, 95% CI 1.21–1.90, Pcorr = 0.004). Identical results were observed in the dominant, recessive, and additive models. In contrast, the G allele of rs7601754 displayed a protective effect against NMOSD (OR = 0.53, 95% CI 0.36–0.76, Pcorr = 0.006). Our study indicates that STAT4 polymorphisms are associated with the risk of NMOSD, which provides novel insights into the underlying mechanisms of this disease
STAT4 Homo sapiens 2q32.2-q32.3 SNP rs7601754 Disease risk The results of multiple test comparisons were corrected using the Benjamini and Hochberg false discovery rate (FDR–BH). After correcting for multiple test comparisons, the minor alleles of four STAT4 SNPs exhibited significant association with increased risk of NMOSD (rs7574865 T, odds ratio [OR] = 1.66, 95% confidence interval [CI] 1.32–2.08, Pcorr = 0.000; rs10181656 G, OR = 1.62, 95% CI 1.29–2.03, Pcorr = 0.000; rs10168266 T, OR = 1.59, 95% CI 1.27–2.00, Pcorr = 0.001; and rs13426947 A, OR = 1.51, 95% CI 1.21–1.90, Pcorr = 0.004). Identical results were observed in the dominant, recessive, and additive models. In contrast, the G allele of rs7601754 displayed a protective effect against NMOSD (OR = 0.53, 95% CI 0.36–0.76, Pcorr = 0.006). Our study indicates that STAT4 polymorphisms are associated with the risk of NMOSD, which provides novel insights into the underlying mechanisms of this disease
STAT4 Homo sapiens 2q32.2-q32.3 SNP rs10168266 Disease risk The results of multiple test comparisons were corrected using the Benjamini and Hochberg false discovery rate (FDR–BH). After correcting for multiple test comparisons, the minor alleles of four STAT4 SNPs exhibited significant association with increased risk of NMOSD (rs7574865 T, odds ratio [OR] = 1.66, 95% confidence interval [CI] 1.32–2.08, Pcorr = 0.000; rs10181656 G, OR = 1.62, 95% CI 1.29–2.03, Pcorr = 0.000; rs10168266 T, OR = 1.59, 95% CI 1.27–2.00, Pcorr = 0.001; and rs13426947 A, OR = 1.51, 95% CI 1.21–1.90, Pcorr = 0.004). Identical results were observed in the dominant, recessive, and additive models. In contrast, the G allele of rs7601754 displayed a protective effect against NMOSD (OR = 0.53, 95% CI 0.36–0.76, Pcorr = 0.006). Our study indicates that STAT4 polymorphisms are associated with the risk of NMOSD, which provides novel insights into the underlying mechanisms of this disease
STAT4 Homo sapiens 2q32.2-q32.3 SNP rs13426947 Disease risk The results of multiple test comparisons were corrected using the Benjamini and Hochberg false discovery rate (FDR–BH). After correcting for multiple test comparisons, the minor alleles of four STAT4 SNPs exhibited significant association with increased risk of NMOSD (rs7574865 T, odds ratio [OR] = 1.66, 95% confidence interval [CI] 1.32–2.08, Pcorr = 0.000; rs10181656 G, OR = 1.62, 95% CI 1.29–2.03, Pcorr = 0.000; rs10168266 T, OR = 1.59, 95% CI 1.27–2.00, Pcorr = 0.001; and rs13426947 A, OR = 1.51, 95% CI 1.21–1.90, Pcorr = 0.004). Identical results were observed in the dominant, recessive, and additive models. In contrast, the G allele of rs7601754 displayed a protective effect against NMOSD (OR = 0.53, 95% CI 0.36–0.76, Pcorr = 0.006). Our study indicates that STAT4 polymorphisms are associated with the risk of NMOSD, which provides novel insights into the underlying mechanisms of this disease
MGMT Homo sapiens 10q26.3 gene polymorphisms N/A Disease risk Hence, we show for the first time that MGMT hypermethylation occurs in chronic diseases that are not strictly associated to distinct pathogens, oncogenic viruses or neoplasms but that lead to damage of the myelin sheath in various ways. While this gives new insights into epigenetic and pathophysiological processes involved in de- and remyelination, which might offer new therapeutic opportunities for demyelinating diseases in the future, it also reduces the specificity of MGMT hypermethylation as a tumor biomarker.
USP18 Homo sapiens 22q11.21 SNP rs2252257 Disease risk Most clinical characteristics of familial NMOSD were indistinguishable from sporadic NMOSD except for the worst episodes severity. USP18 with impaired intronic regulatory function contributed to the pathogenesis of NMOSD
USP18 Homo sapiens 22q11.21 SNP rs361553 Disease risk Most clinical characteristics of familial NMOSD were indistinguishable from sporadic NMOSD except for the worst episodes severity. USP18 with impaired intronic regulatory function contributed to the pathogenesis of NMOSD
USP18 Homo sapiens 22q11.21 SNP rs5746523 Disease risk Most clinical characteristics of familial NMOSD were indistinguishable from sporadic NMOSD except for the worst episodes severity. USP18 with impaired intronic regulatory function contributed to the pathogenesis of NMOSD
FOXP3 Homo sapiens Xp11.23 N/A N/A Disease risk CD4+ Foxp3+ T cells were increased in SLE patients compared with organ-specific autoimmune disease controls or healthy controls. Circulating CD4+ Foxp3+ T cells were correlated with the disease activity of SLE. The increased CD4+ Foxp3+ T cells in active SLE patients were mainly derived from thymus-derived Treg (tTreg) cells, as determined by a demethylated TSDR status, and represented a unique phenotype, upregulated expression of CD49d, CD161, and IL-17A, with immunosuppressive ability comparable to that of healthy controls. Finally, CD4+ Foxp3+ IL-17A+ cells were infiltrated into the renal biopsy specimens of patients with active lupus nephritis.
AR Homo sapiens Xq12 DNA methylation DNA methylation Disease risk We found a strong correlation between dichorionic fetal anatomy and differences in X chromosome inactivation patterns between members of an MZ twin pair. In contrast, all monochorionic twin pairs had closely correlated patterns of X chromosome inactivation. X chromosome inactivation patterns did not distinguish between MZ twin pairs who were concordant or discordant for autoimmune disease
S1PR1 Homo sapiens 1p21.2 DNA methylation DNA methylation Disease risk This study suggests that individual genetic variations of S1P 1 can infl uence receptor function and, therefore, infer differential disease risks and interaction with S1P 1 -targeted therapeutics
FCRL3 Homo sapiens 1q23.1 SNP rs7528684 Disease risk Distribution of Genotype Frequency and the Risk of NMO The case-control analysis demonstrated that rs7528684 (FCRL3_3), rs945635 (FCRL3_5), rs3761959 (FCRL3_6), and rs2282284 (FCRL3_8) showed significant associations with risk of NMO, whereas other 3 SNPs were not. To be specific, the FCRL3_3C, FCRL3_5C, FCRL3_6A, FCRL3_8G allelic frequencies were significantly higher in the case group than those in the control group (OR 1.50, 95% CI: 1.11–2.03, P 0.008; OR 1.44, 95% CI: 1.07–1.94, P 0.015; OR 1.45, 95% CI: 1.08–1.95, P 0.014; OR 2.01, 95% CI: 1.13–3.60, P 0.016). Moreover, their recessive models (except rs3761959) and homozygous models also revealed the remarkable associations between the genetic variants and the risk of NMO. However, the dominant models or the allelic models failed to show any significant correlations between the rest 3 SNPs and the risk of NMO. In addition, haplotype analysis showed that FCRL3_3C, FCRL3_6A, and FCRL3_8G were in a strong linkage disequilibrium (LD), except FCRL3_5
FCRL3 Homo sapiens 1q23.1 SNP rs11264799 Disease risk Distribution of Genotype Frequency and the Risk of NMO The case-control analysis demonstrated that rs7528684 (FCRL3_3), rs945635 (FCRL3_5), rs3761959 (FCRL3_6), and rs2282284 (FCRL3_8) showed significant associations with risk of NMO, whereas other 3 SNPs were not. To be specific, the FCRL3_3C, FCRL3_5C, FCRL3_6A, FCRL3_8G allelic frequencies were significantly higher in the case group than those in the control group (OR 1.50, 95% CI: 1.11–2.03, P 0.008; OR 1.44, 95% CI: 1.07–1.94, P 0.015; OR 1.45, 95% CI: 1.08–1.95, P 0.014; OR 2.01, 95% CI: 1.13–3.60, P 0.016). Moreover, their recessive models (except rs3761959) and homozygous models also revealed the remarkable associations between the genetic variants and the risk of NMO. However, the dominant models or the allelic models failed to show any significant correlations between the rest 3 SNPs and the risk of NMO. In addition, haplotype analysis showed that FCRL3_3C, FCRL3_6A, and FCRL3_8G were in a strong linkage disequilibrium (LD), except FCRL3_5
FCRL3 Homo sapiens 1q23.1 SNP rs945635 Disease risk Distribution of Genotype Frequency and the Risk of NMO The case-control analysis demonstrated that rs7528684 (FCRL3_3), rs945635 (FCRL3_5), rs3761959 (FCRL3_6), and rs2282284 (FCRL3_8) showed significant associations with risk of NMO, whereas other 3 SNPs were not. To be specific, the FCRL3_3C, FCRL3_5C, FCRL3_6A, FCRL3_8G allelic frequencies were significantly higher in the case group than those in the control group (OR 1.50, 95% CI: 1.11–2.03, P 0.008; OR 1.44, 95% CI: 1.07–1.94, P 0.015; OR 1.45, 95% CI: 1.08–1.95, P 0.014; OR 2.01, 95% CI: 1.13–3.60, P 0.016). Moreover, their recessive models (except rs3761959) and homozygous models also revealed the remarkable associations between the genetic variants and the risk of NMO. However, the dominant models or the allelic models failed to show any significant correlations between the rest 3 SNPs and the risk of NMO. In addition, haplotype analysis showed that FCRL3_3C, FCRL3_6A, and FCRL3_8G were in a strong linkage disequilibrium (LD), except FCRL3_5
FCRL3 Homo sapiens 1q23.1 SNP rs3761959 Disease risk Distribution of Genotype Frequency and the Risk of NMO The case-control analysis demonstrated that rs7528684 (FCRL3_3), rs945635 (FCRL3_5), rs3761959 (FCRL3_6), and rs2282284 (FCRL3_8) showed significant associations with risk of NMO, whereas other 3 SNPs were not. To be specific, the FCRL3_3C, FCRL3_5C, FCRL3_6A, FCRL3_8G allelic frequencies were significantly higher in the case group than those in the control group (OR 1.50, 95% CI: 1.11–2.03, P 0.008; OR 1.44, 95% CI: 1.07–1.94, P 0.015; OR 1.45, 95% CI: 1.08–1.95, P 0.014; OR 2.01, 95% CI: 1.13–3.60, P 0.016). Moreover, their recessive models (except rs3761959) and homozygous models also revealed the remarkable associations between the genetic variants and the risk of NMO. However, the dominant models or the allelic models failed to show any significant correlations between the rest 3 SNPs and the risk of NMO. In addition, haplotype analysis showed that FCRL3_3C, FCRL3_6A, and FCRL3_8G were in a strong linkage disequilibrium (LD), except FCRL3_5
FCRL3 Homo sapiens 1q23.1 SNP rs2210913 Disease risk Distribution of Genotype Frequency and the Risk of NMO The case-control analysis demonstrated that rs7528684 (FCRL3_3), rs945635 (FCRL3_5), rs3761959 (FCRL3_6), and rs2282284 (FCRL3_8) showed significant associations with risk of NMO, whereas other 3 SNPs were not. To be specific, the FCRL3_3C, FCRL3_5C, FCRL3_6A, FCRL3_8G allelic frequencies were significantly higher in the case group than those in the control group (OR 1.50, 95% CI: 1.11–2.03, P 0.008; OR 1.44, 95% CI: 1.07–1.94, P 0.015; OR 1.45, 95% CI: 1.08–1.95, P 0.014; OR 2.01, 95% CI: 1.13–3.60, P 0.016). Moreover, their recessive models (except rs3761959) and homozygous models also revealed the remarkable associations between the genetic variants and the risk of NMO. However, the dominant models or the allelic models failed to show any significant correlations between the rest 3 SNPs and the risk of NMO. In addition, haplotype analysis showed that FCRL3_3C, FCRL3_6A, and FCRL3_8G were in a strong linkage disequilibrium (LD), except FCRL3_5
FCRL3 Homo sapiens 1q23.1 SNP rs2282284 Disease risk Distribution of Genotype Frequency and the Risk of NMO The case-control analysis demonstrated that rs7528684 (FCRL3_3), rs945635 (FCRL3_5), rs3761959 (FCRL3_6), and rs2282284 (FCRL3_8) showed significant associations with risk of NMO, whereas other 3 SNPs were not. To be specific, the FCRL3_3C, FCRL3_5C, FCRL3_6A, FCRL3_8G allelic frequencies were significantly higher in the case group than those in the control group (OR 1.50, 95% CI: 1.11–2.03, P 0.008; OR 1.44, 95% CI: 1.07–1.94, P 0.015; OR 1.45, 95% CI: 1.08–1.95, P 0.014; OR 2.01, 95% CI: 1.13–3.60, P 0.016). Moreover, their recessive models (except rs3761959) and homozygous models also revealed the remarkable associations between the genetic variants and the risk of NMO. However, the dominant models or the allelic models failed to show any significant correlations between the rest 3 SNPs and the risk of NMO. In addition, haplotype analysis showed that FCRL3_3C, FCRL3_6A, and FCRL3_8G were in a strong linkage disequilibrium (LD), except FCRL3_5
FCRL3 Homo sapiens 1q23.1 SNP rs2282283 Disease risk Distribution of Genotype Frequency and the Risk of NMO The case-control analysis demonstrated that rs7528684 (FCRL3_3), rs945635 (FCRL3_5), rs3761959 (FCRL3_6), and rs2282284 (FCRL3_8) showed significant associations with risk of NMO, whereas other 3 SNPs were not. To be specific, the FCRL3_3C, FCRL3_5C, FCRL3_6A, FCRL3_8G allelic frequencies were significantly higher in the case group than those in the control group (OR 1.50, 95% CI: 1.11–2.03, P 0.008; OR 1.44, 95% CI: 1.07–1.94, P 0.015; OR 1.45, 95% CI: 1.08–1.95, P 0.014; OR 2.01, 95% CI: 1.13–3.60, P 0.016). Moreover, their recessive models (except rs3761959) and homozygous models also revealed the remarkable associations between the genetic variants and the risk of NMO. However, the dominant models or the allelic models failed to show any significant correlations between the rest 3 SNPs and the risk of NMO. In addition, haplotype analysis showed that FCRL3_3C, FCRL3_6A, and FCRL3_8G were in a strong linkage disequilibrium (LD), except FCRL3_5
CYP4F2 Homo sapiens 19p13.12 SNP rs1558139 Disease risk We revealed CYP4F2 rs1558139 AA genotype association with ON and MS in male. According to statistical analysis, the higher IL-17A levels were determined to be associated with inflammation processes while ON. These findings suggest new biological markers for the diagnostics of ON, but further studies with a larger number of patients, however, are necessary in order to better understand of ON development.
TNFSF13B Homo sapiens 13q33.3 SNP rs374039502 Disease risk In conclusion, in the present study we have failed to identify an association between the TNFSF13B functional variant previously associated with autoimmunity and two immunerelated diseases, GCA and SSc. Thus, this genetic variant does not seem to be responsible for the increased levels of BAFF found in these disorders
CETP Homo sapiens 16q13 SNP rs5882 Disease risk Our study determined that the G/A genotype of CETPrs708272 was associated with two-folddecreased odds of ON development under the codominant (OR = 0.495;95%CI:0.256–0.959) and overdominant (OR = 0.501;95%CI:0.280–0.895) models. Also, each allele C at VEGFArs833068 was associated with 1.7-fold increased odds of ON development under the additive model (OR = 1.733;95% CI:1.148–2.615). Furthermore, IL6 rs1800795 G/G genotype was associated with increased odds of ON development under the codominant (OR = 2.869;95%CI:1.280–6.434) and recessive (OR = 2.315;95% CI:1.251–4.285) models
CETP Homo sapiens 16q13 SNP rs708272 Disease risk Our study determined that the G/A genotype of CETPrs708272 was associated with two-folddecreased odds of ON development under the codominant (OR = 0.495;95%CI:0.256–0.959) and overdominant (OR = 0.501;95%CI:0.280–0.895) models. Also, each allele C at VEGFArs833068 was associated with 1.7-fold increased odds of ON development under the additive model (OR = 1.733;95% CI:1.148–2.615). Furthermore, IL6 rs1800795 G/G genotype was associated with increased odds of ON development under the codominant (OR = 2.869;95%CI:1.280–6.434) and recessive (OR = 2.315;95% CI:1.251–4.285) models
SIRT1 Homo sapiens 10q21.3 SNP rs12778366 Disease risk Our study determined that the G/A genotype of CETPrs708272 was associated with two-folddecreased odds of ON development under the codominant (OR = 0.495;95%CI:0.256–0.959) and overdominant (OR = 0.501;95%CI:0.280–0.895) models. Also, each allele C at VEGFArs833068 was associated with 1.7-fold increased odds of ON development under the additive model (OR = 1.733;95% CI:1.148–2.615). Furthermore, IL6 rs1800795 G/G genotype was associated with increased odds of ON development under the codominant (OR = 2.869;95%CI:1.280–6.434) and recessive (OR = 2.315;95% CI:1.251–4.285) models
FGFR2 Homo sapiens 10q26.13 SNP rs2981582 Disease risk Our study determined that the G/A genotype of CETPrs708272 was associated with two-folddecreased odds of ON development under the codominant (OR = 0.495;95%CI:0.256–0.959) and overdominant (OR = 0.501;95%CI:0.280–0.895) models. Also, each allele C at VEGFArs833068 was associated with 1.7-fold increased odds of ON development under the additive model (OR = 1.733;95% CI:1.148–2.615). Furthermore, IL6 rs1800795 G/G genotype was associated with increased odds of ON development under the codominant (OR = 2.869;95%CI:1.280–6.434) and recessive (OR = 2.315;95% CI:1.251–4.285) models
STAT3 Homo sapiens 17q21.2 SNP rs744166 Disease risk Our study determined that the G/A genotype of CETPrs708272 was associated with two-folddecreased odds of ON development under the codominant (OR = 0.495;95%CI:0.256–0.959) and overdominant (OR = 0.501;95%CI:0.280–0.895) models. Also, each allele C at VEGFArs833068 was associated with 1.7-fold increased odds of ON development under the additive model (OR = 1.733;95% CI:1.148–2.615). Furthermore, IL6 rs1800795 G/G genotype was associated with increased odds of ON development under the codominant (OR = 2.869;95%CI:1.280–6.434) and recessive (OR = 2.315;95% CI:1.251–4.285) models
VEGFA Homo sapiens 6p21.1 SNP rs833068 Disease risk Our study determined that the G/A genotype of CETPrs708272 was associated with two-folddecreased odds of ON development under the codominant (OR = 0.495;95%CI:0.256–0.959) and overdominant (OR = 0.501;95%CI:0.280–0.895) models. Also, each allele C at VEGFArs833068 was associated with 1.7-fold increased odds of ON development under the additive model (OR = 1.733;95% CI:1.148–2.615). Furthermore, IL6 rs1800795 G/G genotype was associated with increased odds of ON development under the codominant (OR = 2.869;95%CI:1.280–6.434) and recessive (OR = 2.315;95% CI:1.251–4.285) models
IL6 Homo sapiens 7p15.3 SNP rs1800795 Disease risk Our study determined that the G/A genotype of CETPrs708272 was associated with two-folddecreased odds of ON development under the codominant (OR = 0.495;95%CI:0.256–0.959) and overdominant (OR = 0.501;95%CI:0.280–0.895) models. Also, each allele C at VEGFArs833068 was associated with 1.7-fold increased odds of ON development under the additive model (OR = 1.733;95% CI:1.148–2.615). Furthermore, IL6 rs1800795 G/G genotype was associated with increased odds of ON development under the codominant (OR = 2.869;95%CI:1.280–6.434) and recessive (OR = 2.315;95% CI:1.251–4.285) models
CD3G Homo sapiens 11q23.3 N/A rs3753058 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
CD44 Homo sapiens 11p13 N/A rs1058200 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
CD44 Homo sapiens 11p13 N/A rs1467558 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
CD5 Homo sapiens 11q12.2 N/A rs637186 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
CD5 Homo sapiens 11q12.2 N/A rs2241002 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
CD69 Homo sapiens 12p13.31 N/A rs3176798 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
PLCG1 Homo sapiens 20q12 N/A rs753381 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
PLCG1 Homo sapiens 20q12 N/A rs8192707 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
PTPN12 Homo sapiens 7q11.23 N/A rs9640663 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
PTPN12 Homo sapiens 7q11.23 N/A rs3750050 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
PTPN3 Homo sapiens 9q31.3 N/A rs101168060 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
PTPN6 Homo sapiens 12p13.31 N/A rs2301262 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
SLAMF1 Homo sapiens 1q23.3 N/A rs164288 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
SLAMF1 Homo sapiens 1q23.3 N/A rs3796504 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
SLAMF1 Homo sapiens 1q23.3 N/A rs2295612 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
PTPN22 Homo sapiens 1p13.2 N/A rs2476601 Disease risk Typing the 41 SNPs with functioning DCE assay (Fischer and Lerman, 1983) in the pooled Norwegian controls (n= 4000) demonstrated that 16 of these (39%) were heterozygous in the Norwegian population , four of these displaying a minor allele frequency of less than 1%
TGFB2 Homo sapiens 1q41 N/A rs10495098 Disease risk We have demonstrated a trend towards association of the 5’ region of TGFB2, including the promoter region and exon 1, with PD. When coupled with the recent observation that TGFb2 appears to have a role in the maintainance of striatal dopamine levels in rodents, this finding provides some support for the hypothesis that variation in the TGFB2 gene influences susceptibility to idiopathic PD. We suggest that the relevance of marker rs6658835 should be explored in other PD cohorts
TGFB2 Homo sapiens 1q41 N/A rs6658835 Disease risk We have demonstrated a trend towards association of the 5’ region of TGFB2, including the promoter region and exon 1, with PD. When coupled with the recent observation that TGFb2 appears to have a role in the maintainance of striatal dopamine levels in rodents, this finding provides some support for the hypothesis that variation in the TGFB2 gene influences susceptibility to idiopathic PD. We suggest that the relevance of marker rs6658835 should be explored in other PD cohorts
TGFB2 Homo sapiens 1q41 N/A rs4846476 Disease risk We have demonstrated a trend towards association of the 5’ region of TGFB2, including the promoter region and exon 1, with PD. When coupled with the recent observation that TGFb2 appears to have a role in the maintainance of striatal dopamine levels in rodents, this finding provides some support for the hypothesis that variation in the TGFB2 gene influences susceptibility to idiopathic PD. We suggest that the relevance of marker rs6658835 should be explored in other PD cohorts
IRF5 Homo sapiens 7q32.1 N/A rs4728142 Disease risk These findings add IRF5 to the short list of genes shown to be associated with MS in more than one population. Our study adds to the evidence that there might be genes or pathways that are common in multiple autoimmune diseases, and that the type I interferon system is likely to be involved in the development of these diseases
IRF5 Homo sapiens 7q32.1 N/A rs3807306 Disease risk These findings add IRF5 to the short list of genes shown to be associated with MS in more than one population. Our study adds to the evidence that there might be genes or pathways that are common in multiple autoimmune diseases, and that the type I interferon system is likely to be involved in the development of these diseases
PON1 Homo sapiens 7q21.3 N/A polymorphism、genotypes and allelic variants Disease risk The results of the present study suggest that PON1 polymorphism is not related with the risk for multiple sclerosis in our population
IL7R Homo sapiens 5p13.2 N/A rs6897932 Disease risk It is known that demographic as well as environmental factors have a substantial role in multiple sclerosis development, as well as population genetic background. The results of this study indicate that other types of genome variants should be required for the development and/or progression of multiple sclerosis, which may vary among populations
IL18R1 Homo sapiens 2q12.1 N/A rs7579737 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 N/A rs7558013 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 N/A rs2241116 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 N/A rs17027056 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 N/A rs4851005 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 N/A rs6706002 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 N/A rs11465597 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 SNP rs10515921 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 SNP rs7603730 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 SNP rs6750020 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 SNP rs3213733 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 SNP rs2041740 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL18R1 Homo sapiens 2q12.1 SNP rs11903946 Disease risk The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
IL7R Homo sapiens 5p13.2 SNP rs6897932 Disease risk Although the power of this study was limited, our preliminary data suggest that disease susceptibility genes in MS in the Indian population may be similar to those of western populations
CLEC16A Homo sapiens 16p13.13 SNP rs 12708716 Disease risk Although the power of this study was limited, our preliminary data suggest that disease susceptibility genes in MS in the Indian population may be similar to those of western populations
CD226 Homo sapiens 18q22.2 SNP rs763361 Disease risk Although the power of this study was limited, our preliminary data suggest that disease susceptibility genes in MS in the Indian population may be similar to those of western populations
CIITA Homo sapiens 16p13.13 SNP rs4774C Disease risk The results show that MS patients without HHV-6 active replication are better responders to interferon beta treatment than those with HHV-6 active replication
CIITA Homo sapiens 16p13.13 SNP rs3087456G Disease risk The results show that MS patients without HHV-6 active replication are better responders to interferon beta treatment than those with HHV-6 active replication
CD40 Homo sapiens 20q13.12 SNP rs1883832C Disease risk Our analysis revealed that individuals possessing CT and TT genotypes (predisposing to MS) had decreased level of CD40 mRNA in comparison to those with CC. Moreover, we demonstrated the potential role of impaired CD40-CD40L interaction in developing of multiple sclerosis
CD40 Homo sapiens 20q13.12 SNP rs11569343C Disease risk Our analysis revealed that individuals possessing CT and TT genotypes (predisposing to MS) had decreased level of CD40 mRNA in comparison to those with CC. Moreover, we demonstrated the potential role of impaired CD40-CD40L interaction in developing of multiple sclerosis
CD40 Homo sapiens 20q13.12 SNP rs752118C Disease risk Our analysis revealed that individuals possessing CT and TT genotypes (predisposing to MS) had decreased level of CD40 mRNA in comparison to those with CC. Moreover, we demonstrated the potential role of impaired CD40-CD40L interaction in developing of multiple sclerosis
CD40LG Homo sapiens Xq26.3 SNP rs3092923T Disease risk Our analysis revealed that individuals possessing CT and TT genotypes (predisposing to MS) had decreased level of CD40 mRNA in comparison to those with CC. Moreover, we demonstrated the potential role of impaired CD40-CD40L interaction in developing of multiple sclerosis
CD40LG Homo sapiens Xq26.3 SNP rs3092952A Disease risk Our analysis revealed that individuals possessing CT and TT genotypes (predisposing to MS) had decreased level of CD40 mRNA in comparison to those with CC. Moreover, we demonstrated the potential role of impaired CD40-CD40L interaction in developing of multiple sclerosis
SOCS1 Homo sapiens 16p13.13 SNP rs243324 Disease risk we found that SOCS1 gene overexpressed in RR-MS patients
VAMP2 Homo sapiens 17p13.1 polymorphisms N/A Disease risk It is the first time that VSEs have been analyzed, and we directly connect the genetic risk factors for MS risk with Vitamin D based on VSEs.
TREM2 Homo sapiens 6p21.1 SNP rs75932628 Disease risk This variant does not seem to play a determining role in the pathogenesis of MS, although further studies examining the presence of TREM2 mutations in other, phylogenetically different populations and the epigenetic regulation of this gene are needed in order to thoroughly investigate its role in MS.
MIR146A Homo sapiens 5q33.3 SNP rs2910164 N/A this study determined that the C and T alleles of rs2910164 and rs1044165 are risk factors for MS in the Iranian population
MIR223 Homo sapiens Xq12 SNP rs1044165 N/A this study determined that the C and T alleles of rs2910164 and rs1044165 are risk factors for MS in the Iranian population
IL1B Homo sapiens 2q14.1 SNP rs35829419 Disease risk positive
HHEX Homo sapiens 10q23.33 SNP rs7923837 Disease risk positive
WAS Homo sapiens Xp11.23 altering histone methylation N/A Treatment risk positive
TAC1 Homo sapiens 7q21.3 SNP rs1510303 Disease risk positive
PRKCA Homo sapiens 17q24.2 SNP rs7220007 Disease risk positive
Spp1 Homo sapiens 4q22.1 SNP rs 4754 Disease risk positive
ERG Homo sapiens 21q22.2 DNA methylation N/A Disease risk positive
HLA-DRB1 Homo sapiens 6p21.32 restriction fragment length polymorphism N/A Disease risk positive
HLA-DQA1 Homo sapiens 6p21.32 restriction fragment length polymorphism N/A Disease risk positive
HLA-DQB1 Homo sapiens 6p21.32 restriction fragment length polymorphism N/A Disease risk Negative
HLA-DPA1 Homo sapiens 6p21.32 restriction fragment length polymorphism N/A Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 restriction fragment length polymorphism N/A Disease risk Negative
TRBV20OR9-2 Homo sapiens 9p13.3 restriction fragment length polymorphism N/A Disease risk Negative
HLA-DPB1 Homo sapiens 6p21.32 restriction fragment length polymorphism N/A Disease risk Negative