Detailed information
| LncRNA Name | HOTAIR |
| Variant Type | SNP |
| Variant ID | rs920778 |
| Species | human |
| Circulating | ✕ |
| Survival | ✕ |
| CeRNA | ✓ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | gastric cancer |
| LncRNA Target Gene | HER2 |
| Tissue | gastric cancer tissue, (AGS, MGC803) cell lines |
| Experiment | genotyping, luciferse reporter assay, real-time PCR |
| Function Description | The rs920778 C>T SNP located in the intronic enhancer region alters the activity of this regulatory element. This may lead to increased HOTAIR expression, which conferring the underlying mechanism of gastric cancer susceptibility. |
| Pubmed ID | 25640751 |
| Year | 2016 |
| Title | A Functional lncRNA HOTAIR Genetic Variant Contributes to Gastric Cancer Susceptibility |
| External Links | |
|---|---|
| Links For HOTAIR | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For gastric cancer | OMIM Cosmic |
| Links For rs920778 | dbSNP ClinVar OMIM |