Detailed information
| LncRNA Name | HOTAIR |
| Variant Type | SNP |
| Variant ID | rs12826786 |
| Species | human |
| Circulating | ✕ |
| Survival | ✓ |
| CeRNA | ✕ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | gastric cardia adenocarcinoma |
| LncRNA Target Gene | NA |
| Tissue | gastric cardia adenocarcinoma tissue, blood |
| Experiment | genotyping, real-time PCR |
| Function Description | The T allele of rs12826786 was found to increase the risk of developing GCA and was associated with smoking habit and tumor-nodemetastasis (TNM) stage. In addition, higher expression levels of HOTAIR were found in tumor tissues and rs12826786 SNP has a genotype-specific effect on HOTAIR expression. A high HOTAIR expression level was associated with poor GCA patients’survival. |
| Pubmed ID | 25476857 |
| Year | 2015 |
| Title | Associations between polymorphisms of HOTAIR and risk of gastric cardia adenocarcinoma in a population of north China |
| External Links | |
|---|---|
| Links For HOTAIR | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For gastric cardia adenocarcinoma | OMIM Cosmic |
| Links For rs12826786 | dbSNP ClinVar OMIM |