LncRNA NameRP11-362K14.5 (CCSlnc362)
Variant TypeSNP
Variant IDrs1317082
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traitcolorectal cancer
LncRNA Target GenemiR-4658
TissueHCT116 and DLD-1 cell lines
ExperimentqRT-PCR; luciferase reporter assays
Function DescriptionThe T>C variant of rs1317082 at CCSlnc362 exon 1 created a binding site for miR-4658 to reduce the expression of CCSlnc362 and thus decreased the susceptibility to CRC.
Pubmed ID30518759
Year2018
TitleVariant of SNP rs1317082 at CCSlnc362(RP11-362K14.5) creates a binding site for miR-4658 and diminishes the susceptibility to CRC
External Links
Links For RP11-362K14.5 (CCSlnc362)GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For colorectal cancer OMIM Cosmic
Links For rs1317082 dbSNP ClinVar OMIM