LncRNA NameGAS5
Variant TypeSNP
Variant IDrs1456204276
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traithepatocellular carcinoma
LncRNA Target GeneNA
Tissuehepatocellular carcinoma tissue, (Sk-Hep-1, BEL-7404, Huh7) cell lines
Experimentgenotyping. Real-time PCR, western blot, luciferase reporter assay
Function DescriptionRs145204276 may contribute to hepatocarcinogenesis by affecting methylation status of the GAS5 promoter and subsequently its transcriptional activity thus serving as a potential therapy target for HCC.
Pubmed ID26163879
Year2015
TitleAssociation between indel polymorphism in the promoter region of lncRNA GAS5 and the risk of hepatocellular carcinoma
External Links
Links For GAS5GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For hepatocellular carcinomaOMIM Cosmic
Links For rs1456204276 dbSNP ClinVar OMIM