Detailed information
| LncRNA Name | ANRIL |
| Variant Type | SNP |
| Variant ID | rs2151280 |
| Species | human |
| Circulating | ✕ |
| Survival | ✕ |
| CeRNA | ✕ |
| Methylation | ✓ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | neurofibromatosis type 1 |
| LncRNA Target Gene | NA |
| Tissue | neurofibromatosis type 1 tissue, blood |
| Experiment | genotyping, real-time PCR |
| Function Description | Single-nucleotide polymorphism rs2151280 (located in ANRIL) was statistically significantly associated with the number of PNFs in NF1 patients. In addition, allele T of rs2151280 was statistically significantly associated with reduced ANRIL transcript levels, suggesting that modulation of ANRIL expression mediates PNF susceptibility. |
| Pubmed ID | 22034633 |
| Year | 2011 |
| Title | Role of Noncoding RNA ANRIL in Genesis of Plexiform Neurofibromas in Neurofibromatosis Type 1 |
| External Links | |
|---|---|
| Links For ANRIL | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For neurofibromatosis type 1 | OMIM Cosmic |
| Links For rs2151280 | dbSNP ClinVar OMIM |