| Disease/Trait | non-cardia gastric cancer |
| LncRNA Target Gene | has-miR-526b |
| Tissue | non-cardia gastric cancer tissue, (293T, HGC-27) cell lines |
| Experiment | genotyping, luciferase reporter assay, qRT-PCR |
| Function Description | LincRNA-NR_024015 rs8506AA carrier was significantly associated with risk of non-cardia gastric cancer, compared with the rs8506 AG or GG genotype.The G to A base change at rs8506G>A disrUp regulationts the binding site for has-miR-526b, thereby influencing the transcriptional activity of lincRNANR_024015 and affecting cell proliferation. |
| Pubmed ID | 24595048 |
| Year | 2014 |
| Title | The has-miR-526b Binding-Site rs8506G>A Polymorphism in the lincRNA-NR_024015 Exon Identified by GWASs Predispose to Non-Cardia Gastric Cancer Risk |