LncRNA Name	MALAT1
Variant Type	SNP
Variant ID	rs619586
Species	human

Circulating	✓
Survival	✕
CeRNA	✓
Methylation	✕
Enhancer	✕
Drug	✕

Disease/Trait	pulmonary arterial hypertension
LncRNA Target Gene	XBP1
Tissue	peripheral blood
Experiment	genotyping; luciferase assays; cell proliferation assay; PCR; western blot
Function Description	We found that the rs619586A > G Further functional experiments indicated that the alteration from rs619586A to G in MALAT1 could directly upregulate X box-binding protein(XBP1) expression via functioning as the competing endogenous RNA (ceRNA) for miR-214single nucleotide polymorphism (SNP) was significantly associated with PAH risk.
Pubmed ID	27362960
Year	2016
Title	Functional polymorphism of lncRNA MALAT1 contributes to pulmonary arterial hypertension susceptibility in Chinese people

External Links
Links For MALAT1	GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For pulmonary arterial hypertension	OMIM Cosmic
Links For rs619586	dbSNP ClinVar OMIM