Detailed information
| LncRNA Name | GAS5 |
| Variant Type | SNP |
| Variant ID | rs55829688 |
| Species | human |
| Circulating | ✕ |
| Survival | ✕ |
| CeRNA | ✕ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | colorectal cancer |
| LncRNA Target Gene | NA |
| Tissue | tissue |
| Experiment | PCR-TaqMan, qPCR, dual-luciferase assay, electrophoretic mobility shift assay (EMSA), flow cytometry, migration and invasion assays |
| Function Description | The dual-luciferase assay, qPCR and EMSA assay revealed that rs55829688 T>C polymorphism could decrease the expression level of GAS5 by impacting the binding ability of the transcription factor Yin Yang-1(YY1) to the GAS5 promoter region. |
| Pubmed ID | 30902880 |
| Year | 2019 |
| Title | Association between polymorphism in the promoter region of lncRNA GAS5 and the risk of colorectal cancer |
| External Links | |
|---|---|
| Links For GAS5 | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For colorectal cancer | OMIM Cosmic |
| Links For rs55829688 | dbSNP ClinVar OMIM |