LncRNA Name	CCAT2
Variant Type	SNP
Variant ID	rs6983267
Species	human and mouse

Circulating	✓
Survival	✕
CeRNA	✕
Methylation	✕
Enhancer	✕
Drug	✕

Disease/Trait	myeloid malignancies
LncRNA Target Gene	NA
Tissue	tissue
Experiment	sanger sequencing; PCR
Function Description	CCAT2 induces global deregulation of gene expression by down-regulating EZH2 in vitro and in vivo in an allele-specific manner. We also identified a novel non-APOBEC, nonADAR, RNA editing at the SNP locus in MDS/MPN patients and CCAT2-transgenic mice.
Pubmed ID	29567676
Year	2018
Title	Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations

External Links
Links For CCAT2	GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For myeloid malignancies	OMIM Cosmic
Links For rs6983267	dbSNP ClinVar OMIM