Detailed information
| LncRNA Name | HOTAIR |
| Variant Type | SNP |
| Variant ID | rs2366152 |
| Species | human |
| Circulating | ✕ |
| Survival | ✕ |
| CeRNA | ✓ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | cervical cancer |
| LncRNA Target Gene | miR-22 |
| Tissue | tissues |
| Experiment | PCR; luciferase assay |
| Function Description | Reduced luciferase activity of a HOTAIR rs2366152C expression plasmid in C33A cells through miR-22 co-transfection confirmed the ability of miR-22 to specifically target rs2366152C-harbouring HOTAIR lncRNA in CaCx cells, ultimately leading to its down-regulation. |
| Pubmed ID | 27683269 |
| Year | 2016 |
| Title | Identification of genetic variation in the lncRNA HOTAIR associated with HPV16-related cervical cancer pathogenesis |
| External Links | |
|---|---|
| Links For HOTAIR | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For cervical cancer | OMIM Cosmic |
| Links For rs2366152 | dbSNP ClinVar OMIM |