Detailed information
| LncRNA Name | CDKN2B |
| Variant Type | SNP |
| Variant ID | rs1333049 |
| Species | human |
| Circulating | ✕ |
| Survival | ✕ |
| CeRNA | ✕ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | coronary artery disease |
| LncRNA Target Gene | p15INK4b |
| Tissue | vascular smooth muscle cells |
| Experiment | real-time PCR |
| Function Description | The results of this study indicate that the 9p21 variation has an impact on CDKN2A and CDKN2B expression in VSMCs and influences VMSC proliferation, which likely represents an important mechanism for the association between this genetic locus and susceptibility to CAD. |
| Pubmed ID | 22706276 |
| Year | 2012 |
| Title | Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells |
| External Links | |
|---|---|
| Links For CDKN2B | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For coronary artery disease | OMIM Cosmic |
| Links For rs1333049 | dbSNP ClinVar OMIM |