Detailed information
| LncRNA Name | GAS5 |
| Variant Type | SNP |
| Variant ID | rs145204276 |
| Species | human |
| Circulating | ✓ |
| Survival | ✓ |
| CeRNA | ✕ |
| Methylation | ✓ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | gastric cancer |
| LncRNA Target Gene | NA |
| Tissue | GC tissues |
| Experiment | qPCR etc. |
| Function Description | Genotype del/del was significantly associated with a higher survival rate. Patients with late tumor stage were found to have a significantly lower rate of genotype del/del than those with an early tumor stage . Patients with UICC III and IV were found to have a significantly lower rate of genotype del/del than those with UICC I and II. The variant rs145204276 of GAS5 is associated with the development and prognosis of GC.The allele del of rs145204276 is associated with a remarkably lower incidence of cancer progression and metastasis. Methylation percentage of the 7th CpG site significantly correlated with GAS5 expression in the tumor tissues |
| Pubmed ID | 29557411 |
| Year | 2018 |
| Title | The Variant rs145204276 of GAS5 is Associated with the Development and Prognosis of Gastric Cancer. |
| External Links | |
|---|---|
| Links For GAS5 | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For gastric cancer | OMIM Cosmic |
| Links For rs145204276 | dbSNP ClinVar OMIM |