LncRNA NameH19
Variant TypeSNP
Variant IDrs217727
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traiturothelial cell carcinoma
LncRNA Target GeneNA
TissueUCC patients and control group
ExperimentRT-PCR etc.
Function DescriptionPatients with UCC carrying the H19 rs217727 CT + TT and rs2107425 CT + TT genetic variants had a high risk of developing muscle invasive tumors (pT2-T4).CT+TT polymorphisms of rs2107425 were associated with worse disease-specific survival in UCC patients aged older than 65 years.
Pubmed ID31013794
Year2019
TitleEffects of Long Noncoding RNA H19 Polymorphisms on Urothelial Cell Carcinoma Development
External Links
Links For H19GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For urothelial cell carcinomaOMIM Cosmic
Links For rs217727 dbSNP ClinVar OMIM