| Disease/Trait | esophageal squamous cell carcinoma |
| LncRNA Target Gene | NA |
| Tissue | (KYSE-30, KYSE-150) cell lines |
| Experiment | genotyping, real-time PCR, luciferase reporter assay |
| Function Description | The rs920778 C>T SNP located in the intronic enhancer region alters the activity of this enhancer, resulting in increased HOTAIR RNA expression, which might be the underlying mechanism in conferring ESCC susceptibility. |
| Pubmed ID | 24788237 |
| Year | 2014 |
| Title | The Identification of a ESCC Susceptibility SNP rs920778 That Regulates the Expression of lncRNA HOTAIR via a Novel Intronic Enhancer |