LncRNA Name	HOTAIR
Variant Type	SNP
Variant ID	rs10783618 C>T
Species	human

Circulating	✓
Survival	✓
CeRNA	✕
Methylation	✕
Enhancer	✕
Drug	✕

Disease/Trait	gastric cardia adenocarcinoma
LncRNA Target Gene	NA
Tissue	blood
Experiment	qPCR, RFLP-PCR etc.
Function Description	Among three htSNPs of the HOTAIR gene (rs12826786 C>T, rs4759314 A>G, and rs10783618 C>T), only the T allele of rs12826786 was found to increase the risk of developing GCA and was associated with smoking habit and tumor-node-metastasis (TNM) stage. In addition, higher expression levels of HOTAIR were found in tumor tissues and rs12826786 SNP has a genotype-specific effetc on HOTAIR expression. A high HOTAIR expression level was associated with poor GCA patients' survival.
Pubmed ID	25476857
Year	2014
Title	Associations between polymorphisms of HOTAIR and risk of gastric cardia adenocarcinoma in a population of north China.

External Links
Links For HOTAIR	GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For gastric cardia adenocarcinoma	OMIM Cosmic
Links For rs10783618 C>T	dbSNP ClinVar OMIM