| Disease/Trait | cervical cancer |
| LncRNA Target Gene | NA |
| Tissue | cervical cancer tissues, cell lines (SiHa, HeLa) |
| Experiment | qPCR, Luciferase reporter assay etc. |
| Function Description | Real-time PCR assay in the 38 normal cervical tissues revealed that HOTAIR mRNA expression level increased with the presence of the risk allele T at rs920778 than those with the CC genotypes. Moreover, the cervical cancer patients with homozygous TT genotype were significantly associated with tumor-node-metastasis (TNM) stage. Furthermore, HOTAIR expression was higher in cervical cancer tissues than that in corresponding normal tissues, and the high expression was associated with the risk-associated allele T. |
| Pubmed ID | 27467165 |
| Year | 2016 |
| Title | Association of Long Non-Coding RNA HOTAIR Polymorphisms with Cervical Cancer Risk in a Chinese Population. |