Detailed information
| LncRNA Name | MALAT1 |
| Variant Type | SNP |
| Variant ID | rs410221 |
| Species | human |
| Circulating | ✕ |
| Survival | ✓ |
| CeRNA | ✕ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | hepatocellular carcinoma |
| LncRNA Target Gene | NA |
| Tissue | hepatocellular carcinoma tissues |
| Experiment | qPCR |
| Function Description | Three SNPs in HOTTIP, one promoter SNP in MALAT1, and one haplotype of HOTTIP were associated with HCC risk. MALAT1 rs4102217 SNP was increased to a 1.32-fold HCC risk under dominant models (P = 0.028). MALAT1 rs591291 showed significantly better prognosis in female and HBV negative subgroups (P = 0.022, HR = 0.37; P = 0.042, HR = 0.25, respectively). |
| Pubmed ID | 29930469 |
| Year | 2018 |
| Title | Association of Twelve Polymorphisms in Three onco-lncRNA Genes With Hepatocellular Cancer Risk and Prognosis: A Case-Control Study |
| External Links | |
|---|---|
| Links For MALAT1 | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For hepatocellular carcinoma | OMIM Cosmic |
| Links For rs410221 | dbSNP ClinVar OMIM |