LncRNA NameSOX2OT
Variant Typecopy number variation
Variant ID3q26.3
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traitlung squamous cell carcinoma
LncRNA Target GeneNA
TissueLSCC tissues
ExperimentqPCR etc.
Function DescriptionIn conclusion, eight out of the nine tested genes were recurrently over-expressed, but SOX2 and SOX2OT were the most consistently highly over-expressed and thus are the best candidates to be driver genes of 3q26.3 amplifications.
Pubmed ID20126410
Year2010
TitleSOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas.
External Links
Links For SOX2OTGeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For lung squamous cell carcinomaOMIM Cosmic
Links For 3q26.3 dbSNP ClinVar OMIM