LncRNA NameTINCR
Variant TypeSNP
Variant IDrs2288947
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traitgastric cancer
LncRNA Target GeneNA
Tissuegastric cancer tissues
ExperimentqPCR etc.
Function DescriptionA allele genotypes of rs8113645 and G allele genotypes of rs2288947 (rs8113645 GA and AA; rs2288947 AG and GG) were also significantly associated with decreased GC risk. Stratification analysis displayed that the correlations between GC risk and variant genotypes of both rs8113645 and rs2288947were more evident in younger individuals, men, nonsmokers, and individuals from rural areas. We also demonstrated that rs8113645 GA+AA genotype carriers had lower TINCR mRNA expression levels compared with common genotype in both normal and GC tissues.
Pubmed ID27893425
Year2016
TitleTag SNPs of long non-coding RNA TINCR affect the genetic susceptibility to gastric cancer in a Chinese population.
External Links
Links For TINCRGeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For gastric cancerOMIM Cosmic
Links For rs2288947 dbSNP ClinVar OMIM