Detailed information
| LncRNA Name | ZNRD1-AS1 |
| Variant Type | SNP |
| Variant ID | rs9261204 |
| Species | human |
| Circulating | ✓ |
| Survival | ✕ |
| CeRNA | ✕ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | lung cancer |
| LncRNA Target Gene | NA |
| Tissue | blood |
| Experiment | qPCR, Genotyping etc. |
| Function Description | we first evaluated the expression ZNRD1-AS1 and ZNRD1 among lung cancer tissues and corresponding normal tissues, which showed higher expression of ZNRD1-AS1 and lower expression of ZNRD1. To reveal the underlying mechanisms, we then investigated the associations between ZNRD1 eQTLs SNPs in ZNRD1-AS1 and risk of lung cancer in Han Chinese populations. G allele of SNP rs9261204 was significantly associated with an increased risk of lung cancer when compared with A allele. A weaker, but similar effect was also observed in bladder cancer. SNP rs3757328 was also associated with increased risk of lung cancer. |
| Pubmed ID | 27166266 |
| Year | 2016 |
| Title | Strong evidence for LncRNA ZNRD1-AS1, and its functional Cis-eQTL locus contributing more to the susceptibility of lung cancer |
| External Links | |
|---|---|
| Links For ZNRD1-AS1 | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For lung cancer | OMIM Cosmic |
| Links For rs9261204 | dbSNP ClinVar OMIM |