Detailed information
| LncRNA Name | circTUBB |
| Variant Type | SNP |
| Variant ID | rs25497 |
| Species | human |
| Circulating | ✕ |
| Survival | ✕ |
| CeRNA | ✕ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | colorectal cancer |
| LncRNA Target Gene | NA |
| Tissue | colorectal cancer cell lines |
| Experiment | other |
| Function Description | rs25497 in circTUBB was significantly associated with colorectal cancer risk in a Chinese population after false discovery rate (FDR) correction [odds ratio (OR) = 1.78, 95% confidence interval (CI) = 1.44-2.21, P=1.42×10-7, PFDR=2.80×10-5] and even reached significance in a genome-wide association study (GWAS) under the dominant model (P=1.28×10-8). |
| Pubmed ID | 31797002 |
| Year | 2019 |
| Title | Genetic variants in circTUBB interacting with smoking can enhance colorectal cancer risk |
| External Links | |
|---|---|
| Links For circTUBB | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For colorectal cancer | OMIM Cosmic |
| Links For rs25497 | dbSNP ClinVar OMIM |